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| 1 | Recurrence after endoscopic piecemeal mucosal resection for large sessile colorectal polyps显示文摘AIM: To evaluate the safety and outcomes of endoscopic piecemeal mucosal resection (EPMR) for large sessile colorectal polyps. METHODS: The patients enrolled in this study were 47 patients with 50 large sessile polyps (diameter, 2 cm or greater) who underwent EPMR using a submucosal saline injection technique between December 2002 and October 2005. All medical records, including characteristics of the patients and polyps, complications, and recurrences, were retrospectively reviewed. The first follow-up endoscopic examination was performed at 3-6 mo after initial endoscopic resection, and the second at 12 mo postEPMR. Subsequent surveillance colonoscopic examinations were individualized, taking risk factors into account. RESULTS: The patients were 23 men and 24 women,with a mean age of 60 years. Mean polyp size was 30.1 mm. Of 50 polyps identified, 34 (68%) were benign and 16 (32%) were malignant. There were 6 (12%) cases with EPMR-related bleeding: 5 intra-procedural and 1 early post-procedural bleeding. All bleeding episodes were managed by endoscopic clipping or argon beam coagulation. There were no perforations. Recurrence was identified in 5 cases (12.2%): 4 local recurrences detected at 3 mo post-EPMR and 1 local recurrence detected at 14 mo post-EPMR. The recurrence rate after EPMR was 3.1% for benign polyps and 33.3% for malignant polyps (P < 0.05). Median follow-up time was 37 mo. CONCLUSION: EPMR is safe, but should be applied carefully in malignant polyps. Close follow-up endoscopic examinations are necessary for early detection of recurrence. | Guh Jung Seo Dae Kyung Sohn Kyung Su Han Chang Won Hong Byung Chang Kim Ji Won Park Hyo Seong Choi Hee Jin Chang Jae Hwan Oh | 2010 | World Journal of Gastroenterology2010，16，22： | 17 |
| 2 | Open versus laparoscopic surgery for mid or low rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): short-term outcomes of an open-label randomised controlled trial显示文摘 | Sung-Bum Kang Ji Won Park Seung-Yong Jeong Byung Ho Nam Hyo Seong Choi Duck-Woo Kim Seok-Byung Lim Taek-Gu Lee Dae Yong Kim Jae-Sung Kim Hee Jin Chang Hye-Seung Lee Sun Young Kim Kyung Hae Jung Yong Sang Hong Jee Hyun Kim Dae Kyung Sohn Dae-Hyun Kim Jae H | 2010 | Lancet Oncology2010，，7： | 5 |
| 3 | Different risk factors for advanced colorectal neoplasm in young adults显示文摘AIM: To compare the risk of developing advanced colorectal neoplasm(ACRN) according to age in Koreans.METHODS: A total of 70428 Koreans from an occupational cohort who underwent a colonoscopy between 2003 and 2012 at Kangbuk Samsung Hospital were retrospectively selected. We evaluated and compared odds ratios(OR) for ACRN between the young-adults(YA < 50 years) and in the older-adults(OA ≥ 50 years). ACRN was defined as an adenoma ≥ 10 mm in diameter, adenoma with any component of villous histology, high-grade dysplasia, or invasive cancer.RESULTS: In the YA group, age(OR = 1.08, 95%CI: 1.06-1.09), male sex(OR = 1.26, 95%CI: 1.02-1.55), current smoking(OR = 1.37, 95%CI: 1.15-1.63), family history of colorectal cancer(OR = 1.46, 95%CI: 1.01-2.10), diabetes mellitus related factors(OR = 1.27, 95%CI: 1.06-1.54), obesity(OR = 1.23, 95%CI: 1.03-1.47), CEA(OR = 1.04, 95%CI: 1.01-1.09) and low-density lipoprotein-cholesterol(OR = 1.01, 95%CI: 1.01-1.02) were related with an increased risk of ACRN. However, age(OR = 1.08, 95%CI: 1.06-1.09), male sex(OR = 2.12, 95%CI: 1.68-2.68), current smoking(OR = 1.38, 95%CI: 1.12-1.71), obesity(OR = 1.34, 95%CI: 1.09-1.65) and CEA(OR = 1.05, 95%CI: 1.01-1.09) also increased the risk of ACRN in the OA group.CONCLUSION: The risks of ACRN differed based on age group. Different colonoscopic screening strategies are appropriate for particular subjects with risk factors for ACRN, even in subjects younger than 50 years. | Ji Yeon Kim Yoon Suk Jung Jung Ho Park Hong Joo Kim Yong Kyun Cho Chong Il Sohn Woo Kyu Jeon Byung Ik Kim Kyu Yong Choi Dong Il Park | 2016 | World Journal of Gastroenterology2016，22，13： | 5 |
| 4 | Efficacy of Pegylated Interferon Monotherapy versus Sequential Therapy of Entecavir and Pegylated Interferon in Hepatitis B e Antigen-Positive Hepatitis B Patients: A Randomized, Multicenter, Phase IIIb Open-Label Study (POTENT Study)显示文摘 | Dae Won Jun Sang Bong Ahn Tae Yeob Kim Joo Hyun Sohn Sang Gyune Kim Se Whan Lee Byung Ho Kim Dong Joon Kim Ja Kyung Kim Hyoung Su Kim Seong Gyu Hwang Won Choong Choi Won Young Tak Heon Ju Lee Ki Tae Yoon Byung Cheol Yun Sung Wook Lee Soon Koo Baik Seung Ha Park Ji Won Park Sol Ji Park Ji Sung Lee | 2018 | Chinese Medical Journal2018，，14： | 5 |
| 5 | Open versus laparoscopic surgery for mid-rectal or low-rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): survival outcomes of an open-label, non-inferiority, randomised controlled trial显示文摘 | Seung-Yong Jeong Ji Won Park Byung Ho Nam Sohee Kim Sung-Bum Kang Seok-Byung Lim Hyo Seong Choi Duck-Woo Kim Hee Jin Chang Dae Yong Kim Kyung Hae Jung Tae-You Kim Gyeong Hoon Kang Eui Kyu Chie Sun Young Kim Dae Kyung Sohn Dae-Hyun Kim Jae-Sung Kim Hye Seu | 2014 | Lancet Oncology2014，，7： | 3 |
| 6 | Surface plasmon enhancement of photoluminescence in photo-chemically synthesized graphene quantum dot and Au nanosphere显示文摘Graphene 量点(GQD ) 为象新奇 optoelectronic 设备和简历成像那样的潜在的应用正在答应候选人。然而,展出他们的吸引人的特征的不够的轻吸收。Au nanoparticles 作为一条天线引起的光的强壮的监禁能更加增加轻吸收。与紫外照耀的帮助,我们由 GQD 和 Au nanoparticles (GQD/Au ) 的杂交准备了带蓝色绿色的光 nanospheres。这些 nanospheres 显示出多达 26.9% 的光致发光量收益。GQD/Au nanospheres 被一个光化学的方法与 GQD 和金属性的 Au 的形成的减小用 GQD 和 HAuCl4 的一个答案综合。进经由 aurophilicity 和氢结合相互作用的 nanospheres 自我装配、聚集的 GQD 和 Au nanoparticles。GQD/Au nanospheres 的平均尺寸被发现在 150-170 nm 的范围,它比太古的 GQD (4-7 nm ) 的大得多。GQD/Au nanospheres 在 541 nm 展出了一个吸收乐队,它在 nanospheres 显示 Au 的存在。GQD 的典型吸收度特征在 236 和 303 nm 附近被观察。光致发光特征用刺激和排放系列被调查。GQD/Au nanospheres 在可见范围在 468 和 529 nm 展出了二座排放山峰。绿色荧光灯在 529 nm 定位的山峰被杂交最新产生。GQD/Au nanospheres 看排放效率哪个是多于内在的 GQD 的 two times。为这增加的原因是从 Au 粒子的表面电浆子回声,它改进了产生 nanospheres 的荧光性质。这些 nanospheres 能与高排放紧张作为象生物样品的显示, optoelectronic 设备,和成像那样的应用的突出的候选人被察觉。 | Byeongho Park Sun Jun Kim Ji Soo Sohn Min Sik Nam Shinill Kang Seong Chan Jun | 2016 | Nano Research2016，9，6： | 3 |
| 7 | Predictors for difficult cecal insertion in colonoscopy: The impact of obesity indices显示文摘AIM To identify the factors influencing cecal insertion time(CIT) and to evaluate the effect of obesity indices on CIT. METHODS We retrospectively reviewed the data for participants who received both colonoscopy and abdominal computed tomography(CT) from February 2008 to May 2008 as part of a comprehensive health screening program. Age, gender, obesity indices [body mass index(BMI), waist-to-hip circumference ratio(WHR), waist circumference(WC), visceral adipose tissue(VAT)volume and subcutaneous adipose tissue(SAT) volume on abdominal CT], history of prior abdominal surgery, constipation, experience of the colonoscopist, quality of bowel preparation, diverticulosis and time required to reach the cecum were analyzed. CIT was categorized as longer than 10 min(prolonged CIT) and shorter than or equal to 10 min, and then the factors that required a CIT longer than 10 min were examined.RESULTS A total of 1678 participants were enrolled. The mean age was 50.42 ± 9.931 years and 60.3% were men. The mean BMI, WHR, WC, VAT volume and SAT volume were 23.92 ± 2.964 kg/m2, 0.90 ± 0.076, 86.95 ± 8.030 cm, 905.29 ± 475.220 cm3 and 1707.72 ± 576.550 cm3, respectively. The number of patients who underwent abdominal surgery was 268(16.0%). Colonoscopy was performed by an attending physician alone in 61.9% of cases and with the involvement of a fellow in 38.1% of cases. The median CIT was 7 min(range 2-56 min, IQR 5-10 min), and mean CIT was 8.58 ± 5.291 min. Being female, BMI, VAT volume and involvement of fellow were significantly associated with a prolonged CIT in univariable analysis. In multivariable analysis, being female(OR = 1.29, P = 0.047), lower BMI(< 23 kg/m2)(OR = 1.62, P = 0.004) or higher BMI(≥ 25 kg/m2)(OR = 1.80, P < 0.001), low VAT volume(< 500 cm3)(OR = 1.50, P = 0.013) and fellow involvement(OR = 1.73, P < 0.001) were significant predictors of prolonged CIT. In subgroup analyses for gender, lower BMI or higher BMI and fellow involvement were predictors for prolonged CIT in both genders. However, low VAT volume was associated with prolonged CIT in only women(OR = 1.54, P = 0.034).CONCLUSION Being female, having a lower or higher BMI than the normal range, a low VAT volume, and fellow involvement were predictors of a longer CIT. | Soo Yun Moon Byung Chang Kim Dae Kyung Sohn Kyung Su Han Bun Kim Chang Won Hong Bum Joon Park Kum Hei Ryu Ji Hyung Nam | 2017 | World Journal of Gastroenterology2017，23，13： | 3 |
| 8 | Predictive Factors for Lymph Node Metastasis in Early Gastric Cancer With Submucosal Invasion: Analysis of a Single Institutional Experience显示文摘 | Ji Yeong An Yong Hae Baik Min Gew Choi Jae Hyung Noh Tae Sung Sohn Sung Kim | 2007 | Annals of Surgery2007，，5： | 2 |
| 9 | Micropapillary Carcinoma of Stomach: A Clinicopathologic and Immunohistochemical Study of 11 Cases显示文摘 | Ji Hyeon Roh Amitabh Srivastava Gregory Y. Lauwers Jungsuk An Kee-Taek Jang Cheol Keun Park Tae Sung Sohn Sung Kim Kyoung-Mee Kim | 2010 | The American Journal of Surgical Pathology2010，，8： | 2 |
| 10 | The outcome of patients with remnant primary gastric cancer compared with those having upper one-third gastric cancer显示文摘 | Ji Yeong An Min-Gew Choi Jae Hyung Noh Tae Sung Sohn Sung Kim | 2007 | The American Journal of Surgery2007，，2： | 2 |
| 11 | Neoadjuvant Chemoradiotherapy Affects the Indications for Lateral Pelvic Node Dissection in Mid/Low Rectal Cancer with Clinically Suspected Lateral Node Involvement: A Multicenter Retrospective Cohort Study显示文摘 | Heung-Kwon Oh Sung-Bum Kang Sung-Min Lee Soo Young Lee Myoung Hun Ihn Duck-Woo Kim Ji Hoon Park Young Hoon Kim Kyung Ho Lee Jae-Sung Kim Jin Won Kim Jee Hyun Kim Tae-Young Chang Sung-Chan Park Dae Kyung Sohn Jae Hwan Oh Ji Won Park Seung-Bum Ryoo Seung-Yo | 2014 | Annals of Surgical Oncology2014，，： | 2 |
| 12 | 来自一项艾日布林联合吉西他滨对比紫杉醇联合吉西他滨作为HER2阴性转移性乳腺癌的一线化疗的Ⅱ期、多中心、随机试验的包含神经病变相关量表的生活质量结果:韩国癌症研究组试验(KCSG BR13-11)显示文摘背景与目的一项比较艾日布林联合吉西他滨(eribulin plus gemcitabine,EG)或紫杉醇联合吉西他滨(paclitaxel plus gemcitabine,PG)作为转移性乳腺癌(metastatic breast cancer,MBC)患者一线化疗方案的II期临床试验发现,EG方案的神经毒性较低,但疗效与PG方案相似。在本研究中,我们分析了该临床实验中的癌症患者生命质量测评量表–紫杉烷(functional assessment of cancer therapy-taxane,FACT-Taxane)问卷评分以确定他们的生活质量(quality of life,QoL)。方法使用韩国版的FACT-Taxane问卷评估QoL。在评估基线之后,前12个疗程中每2个疗程评估1次QoL,之后每3个疗程评估1次QoL。使用线性混合模型评估EG组和PG组QoL的差异。结果在118例入组患者中,117例在基线时回复了FACT-Taxane问卷,PG组中有1例患者没有回复。EG组和PG组之间的基线QoL评分没有差异。在治疗期间,除了第11个疗程外,在第2–13个化疗疗程后,PG组紫杉烷亚量表评分显著高于EG组(均P<0.05)。神经病变特异性分析显示PG组患者的神经病症状比EG组患者更早出现且更严重(P<0.001)。结论在我们的QoL分析中,与PG方案相比,EG方案延迟并减少神经病变的发生。因此,艾日布林是MBC一线化疗药物紫杉醇的合理替代品。 | Ji‑Yeon Kim Seri Park Seock‑Ah Im Sung‑Bae Kim Joohyuk Sohn Keun Seok Lee Yee Soo Chae Ki Hyeong Lee Jee Hyun Kim Young‑Hyuck Im Tae‑Yong Kim Kyung‑Hun Lee Jin‑Hee Ahn Gun Min Kim In Hae Park Soo Jung Lee Hye Sook Han Se Hyun Kim Kyung Hae Jung Yeon Hee Park Korean Cancer Study Group | 2019 | 癌症2019，38，8： | 2 |
| 13 | Association of colorectal adenoma with components of metabolic syndrome显示文摘 | Byung Kim Aesun Shin Chang Hong Dae Sohn Kyung Han Kum Ryu Bum Park Ji Nam Ji Park Hee Chang Hyo Choi Jeongseon Kim Jae Oh | 2012 | Cancer Causes & Control2012，，5： | 2 |
| 14 | A study of metachronous cancer after endoscopic resection of early gastric cancer显示文摘 | Ji Sun Han Jin Seok Jang Seok Reyol Choi Hyuk Chan Kwon Min Chan Kim Jin Sook Jeong Su Jin Kim You Jung Sohn Eun Joo Lee | 2011 | Scandinavian Journal of Gastroenterology2011，，9： | 2 |
| 15 | Adaptor Protein Complex 2–Mediated Endocytosis Is Crucial for Male Reproductive Organ Development in Arabidopsis[W]显示文摘 | Soo Youn Kim Zheng-Yi Xu Kyungyoung Song Dae Heon Kim Hyangju Kang Ilka Reichardt Eun Ju Sohn Ji?í Friml Gerd Juergens Inhwan Hwang | 2013 | The Plant Cell2013，，8： | 1 |
| 16 | Flow injection analysis system for monitoring of succinic acid in biotechnological proceses显示文摘 | Sohn OJ Hart KA Rbee JI | 2005 | Talanta2005，65，1： | 1 |
| 17 | Clinical Significance of Splenic Hilar Lymph Node Metastasis in Proximal Gastric Cancer显示文摘 | Suk Hee Shin MD Hun Jung MD Seong Hee Choi MD Ji Yeong An MD Min Gew Choi MD Jae Hyung Noh MD Tae Sung Sohn MD Jae Moon Bae MD Sung Kim MD | 2009 | Annals of Surgical Oncology2009，，5： | 1 |
| 18 | Endothelium-dependent sensory non-adrenergic non-cholinergic vasodilatation in rat thoracic aorta: involvement of ATP and a role for NO显示文摘 | Park JI Shin CY Lee YW Huh IH Sohn UD | 2000 | J Pharm Pharmacol2000，52，4： | 1 |
| 19 | A Comparative Study of Outcomes Between Endoscope Sphincterotomy Plus Endoscope Papillary Large Balloon Dilatation and Endoscopic Sphincterotomy Alone in Patients with Large Extrahepatic Bile Duct Stones显示文摘 | Tae Hyeon Kim Hyo Jeong Oh Chong Ju Im Chang Soo Choi Ji Hye Kweon Young Woo Sohn | 2009 | Gastrointestinal Endoscopy2009，，5： | 1 |
| 20 | Expression of Myeloid Antigen in Neoplastic Plasma Cells Is Related to Adverse Prognosis in Patients with Multiple Myeloma显示文摘 | Hyoeun Shim Joo Hee Ha Hyewon Lee Ji Yeon Sohn Hyun Ju Kim Hyeon-Seok Eom Sun-Young Kong Dong Soon Lee | 2014 | BioMed Research International2014，，： | 1 |
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