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| 1 | Assessment of scoring systems for acute-on-chronic liver failure at predicting short-term mortality in patients with alcoholic hepatitis显示文摘AIM To assess the performance of proposed scores specific for acute-on-chronic liver failure in predicting shortterm mortality among patients with alcoholic hepatitis.METHODS We retrospectively collected data from 264 patients with clinically diagnosed alcoholic hepatitis from January to December 2013 at 21 academic hospitals in Korea. The performance for predicting short-term mortality was calculated for Chronic Liver FailureSequential Organ Failure Assessment(CLIF-SOFA), CLIF Consortium Organ Failure score(CLIF-C OFs), Maddrey'sdiscriminant function(DF), age, bilirubin, international normalized ratio and creatinine score(ABIC), Glasgow Alcoholic Hepatitis Score(GAHS), model for end-stage liver disease(MELD), and MELD-Na.RESULTS Of 264 patients, 32(12%) patients died within 28 d. The area under receiver operating characteristic curve of CLIF-SOFA, CLIF-C OFs, DF, ABIC, GAHS, MELD, and MELD-Na was 0.86(0.81-0.90), 0.89(0.84-0.92), 0.79(0.74-0.84), 0.78(0.72-0.83), 0.81(0.76-0.86), 0.83(0.78-0.88), and 0.83(0.78-0.88), respectively, for 28-d mortality. The performance of CLIF-SOFA had no statistically significant differences for 28-d mortality. The performance of CLIF-C OFs was superior to that of DF, ABIC, and GAHS, while comparable to that of MELD and MELD-Na in predicting 28-d mortality. A CLIF-SOFA score of 8 had 78.1% sensitivity and 79.7% specificity, and CLIF-C OFs of 10 had 68.8% sensitivity and 91.4% specificity for predicting 28-d mortality.CONCLUSION CLIF-SOFA and CLIF-C OF scores performed well, with comparable predictive ability for short-term mortality compared to the commonly used scoring systems in patients with alcoholic hepatitis. | Hee Yeon Kim Chang Wook Kim Tae Yeob Kim Do Seon Song Dong Hyun Sinn Eileen L Yoon Young Kul Jung Ki Tae Suk Sang Soo Lee Chang Hyeong Lee Tae Hun Kim Jeong Han Kim Hyung Joon Yim Sung Eun Kim Soon Koo Baik Byung Seok Lee Jae Young Jang Young Seok Kim Sang Gyune Kim Jin Mo Yang Joo Hyun Sohn Heon Ju Lee Seung Ha Park Eun Hee Choi Dong Joon Kim Korean Acute-on-Chronic Liver Failure Study Group | 2016 | World Journal of Gastroenterology2016，22，41： | 5 |
| 2 | Anxiety and depression propensities in patients with acute toxic liver injury显示文摘AIM:To investigate anxiety and depression propensities in patients with toxic liver injury.METHODS:The subjects were divided into three groups:a healthy control group(Group 1,n=125),an acute non-toxic liver injury group(Group 2,n=124),and a group with acute toxic liver injury group caused by noncommercial herbal preparations(Group 3,n=126).These three groups were compared and evaluated through questionnaire surveys and using the Hospital Anxiety-Depression Scale(HADS),Beck Anxiety Inventory(BAI),Beck Depression Inventory(BDI),and the hypochondriasis scale.RESULTS:The HADS anxiety subscale was 4.9±2.7,5.0±3.0 and 5.6±3.4,in Groups 1,2,and 3,respectively.The HADS depression subscale in Group 3 showed the most significant score(5.2±3.2,6.4±3.4 and 7.2±3.4in Groups 1,2,and 3,respectively)(P<0.01 vs Group 1,P<0.05 vs Group 2).The BAI and BDI in Group 3showed the most significant score(7.0±6.3 and 6.9±6.9,9.5±8.6 and 8.8±7.3,10.7±7.2 and 11.6±8.5in Groups 1,2,and 3,respectively)(BAI:P<0.01 vs Group 1,P<0.05 vs Group 2)(BDI:P<0.01 vs Group1 and 2).Group 3 showed a significantly higher hypochondriasis score(8.2±6.0,11.6±7.5 and 13.1±6.5in Groups 1,2,and 3,respectively)(P<0.01 vs Group 1,P<0.05 vs Group 2).CONCLUSION:Psychological factors that present vulnerability to the temptation to use alternative medicines,such as herbs and plant preparations,are important for understanding toxic liver injury. | Jeong Ill Suh Jeong Kyu Sakong Kwan Lee Yong Kook Lee Jeong Bae Park Dong Joon Kim Yeon Seok SeoDepartment of Internal Medicine Korea University Anam Hospital Korea University College of Medicine Seoul 136-705 South Korea Jae Dong Lee Soon Young Ko Byung Seok Lee Seok Hyun Kim Byung Seok Kim Young Seok Kim Heon Ju Lee In Hee Kim Joo Hyun Sohn Tae Yeob Kim Byung Min Ahn | 2013 | World Journal of Gastroenterology2013，19，47： | 5 |
| 3 | Efficacy of Pegylated Interferon Monotherapy versus Sequential Therapy of Entecavir and Pegylated Interferon in Hepatitis B e Antigen-Positive Hepatitis B Patients: A Randomized, Multicenter, Phase IIIb Open-Label Study (POTENT Study)显示文摘 | Dae Won Jun Sang Bong Ahn Tae Yeob Kim Joo Hyun Sohn Sang Gyune Kim Se Whan Lee Byung Ho Kim Dong Joon Kim Ja Kyung Kim Hyoung Su Kim Seong Gyu Hwang Won Choong Choi Won Young Tak Heon Ju Lee Ki Tae Yoon Byung Cheol Yun Sung Wook Lee Soon Koo Baik Seung Ha Park Ji Won Park Sol Ji Park Ji Sung Lee | 2018 | Chinese Medical Journal2018，，14： | 5 |
| 4 | Risk assessment for the development of hepatocellular carcinoma: According to on-treatment viral response during long-term lamivudine therapy in hepatitis B virus-related liver disease显示文摘 | Jong Ryul Eun Heon Ju Lee Tae Nyeun Kim Kyeung Soo Lee | 2010 | Journal of Hepatology2010，，1： | 3 |
| 5 | Atypical onset of bicalutamide-induced liver injury显示文摘Anti-androgen therapy is the leading treatment for advanced prostate cancer and is commonly used for neoadjuvant or adjuvant treatment. Bicalutamide is a non-steroidal anti-androgen, used during the initiation of androgen deprivation therapy along with a luteinizing hormone-releasing hormone agonist to reduce the symptoms of tumor-related flares in patients with advanced prostate cancer. As side effects, bicalutamide can cause fatigue, gynecomastia, and decreased libido through competitive androgen receptor blockade. Additionally, although not as common, drug-induced liver injury has also been reported. Herein, we report a case of hepatotoxicity secondary to bicalutamide use. Typically, bicalutamideinduced hepatotoxicity develops after a few days; however, in this case, hepatic injury occurred 5 mo after treatment initiation. Based on this rare case of delayed liver injury, we recommend careful monitoring of liver function throughout bicalutamide treatment for prostate cancer. | Gee Young Yun Seok Hyun Kim Seok Won Kim Jong Seok Joo Ju Seok Kim Eaum Seok Lee Byung Seok Lee Sun Hyoung Kang Hee Seok Moon Jae Kyu Sung Heon Young Lee Kyung Hee Kim | 2016 | World Journal of Gastroenterology2016，22，15： | 3 |
| 6 | Risk assessment for the development of hepatocellular carcinoma: According to on-treatment viral response during long-term lamivudine therapy in hepatitis B virus-related liver disease显示文摘 | Jong Ryul Eun Heon Ju Lee Tae Nyeun Kim Kyeung Soo Lee | 2010 | Journal of Hepatology2010，，1： | 1 |
| 7 | Effect of Bi 12 (Ti 1/2 Si 1/2 )O 20 on the low temperature sintering of Bi 2 (Zn 1/3 Nb 2/3 ) 2 O 7 ceramics and their microwave dielectric properties显示文摘 | Hun Ju Cha Young Seok Lee Jong Yoon Ha Dong Joo Kim Dong Heon Kang | 2007 | Materials Research Bulletin2007，，8： | 1 |
| 8 | Fabrication of perovskite solar cell with high short-circuit current density(Jsc)using moth-eye structure of SiOx显示文摘The performance of solar cells is determined by three factors:the open-circuit voltage(Voc),short-circuit current density(Jsc),and fill factor(FF).The Voc and FF are determined by the material bandgap and the series/shunt resistance,respectively.However,Jsc is determined by the amount of incident light in addition to the bandgap of the material.In this study,a moth-eye pattern was formed on a glass surface via direct printing to increase the amount of incident light and thus increase Jsc-The moth-eye pattern is a typical antireflection pattern that reduces the reflection by gradually increasing the refractive index.A flat perovskite solar cell(F-PSC)and a moth-eye patterned perovskite solar cell(M-PSC)had Jsc values of 23.70 and 25.50 mA/cm^2,respectively.The power-conversion efficiencies of the F-PSC and M-PSC were 19.81%and 21.77%,respectively. | Sucheol Ju Minseop Byun Minjin Kim Junho Jun Daihong Huh Dong Suk Kim Yimhyun Jo Heon Lee | 2020 | Nano Research2020，13，4： | 1 |
| 9 | The dynamic modeling and analysis for an omnidirectional mobile robot with three caster wheels显示文摘 | Chung Jae Heon Yi Byung Ju Kim Whee Kuk Lee Hogil | 1994 | Mobile Robot IEEE1994，，3： | 1 |
| 10 | Response surface optimised extraction and chromatographic purification of rosmarinic acid from Melissa officinalis leaves显示文摘 | Sooah Kim Eun Ju Yun Jin Seop Bak Hojoung Lee Sung Joon Lee Cheong Tae Kim Jong-Hoon Lee Kyoung Heon Kim | 2009 | Food Chemistry2009，，2： | 1 |
| 11 | Removal of sulfur dioxide and nitrogen oxides by using ozone injection and absorption reduction technique显示文摘 | Young Sun Mok Heon Ju Lee | 2006 | Fuel Processing Technology2006，87，： | 1 |
| 12 | Modulation of lipid metabolism by polyphenol‐rich grape skin extract improves liver steatosis and adiposity in high fat fed mice显示文摘 | Hae‐Jin Park Un Ju Jung Mi‐Kyung Lee Su‐Jung Cho Hee‐Kyoung Jung Joo Heon Hong Yong Bok Park Sang Ryong Kim Sangphil Shim Jieun Jung Myung‐Sook Choi | 2012 | Mol. Nutr. Food Res2012，，2： | 1 |
| 13 | A nationwide seroepidemiology of hepatitis C virus infection in South Korea显示文摘 | Do Young Kim In Hee Kim Sook‐Hyang Jeong Yong Kyun Cho Joon Hyoek Lee Young‐Joo Jin Don Lee Dong Jin Suh Kwang‐Hyub Han Neung Hwa Park Ha Yan Kang Young Kul Jung Young Seok Kim Kyung‐Ah Kim Youn Jae Lee Byung Seok Lee Hyung Joon Yim Heon Ju Lee Soon Koo B | 2013 | Liver Int2013，，4： | 1 |
| 14 | Low temperature propylene SCR of NO by copper alumina catalyst显示文摘 | Pullur Anil Kumar Maddigapu Pratap Reddy Lee Kyung Ju Bae Hyun-Sook Ha Heon Phil | 2008 | Journal of Molecular Catalysis A Chemical2008，，1： | 1 |
| 15 | Anthocyanin changes in the Korean purple-fleshed sweet potato, Shinzami, as affected by steaming and baking显示文摘 | Heon Woong Kim Jung Bong Kim Soo Muk Cho Mi Nam Chung Young Min Lee Sang Mi Chu Jeong Hwan Che Se Na Kim So Young Kim Young Sook Cho Jae Hyun Kim Hong Ju Park Dong Jin Lee | 2011 | Food Chemistry2011，，： | 1 |
| 16 | Pentoxifylline versus corticosteroid to treat severe alcoholic hepatitis: A randomised, noninferiority, open trial显示文摘 | Seung Ha Park Dong Joon Kim Young Seok Kim Hyung Joon Yim Won Young Tak Heon Ju Lee Joo Hyun Sohn Ki Tae Yoon In Hee Kim Hyoung Su Kim Soon Ho Um Soon Koo Baik June Sung Lee Ki Tae Suk Sang Gyune Kim Sang Jun Suh Soo Young Park Tae Yeob Kim Jae Young Jang | 2014 | Journal of Hepatology2014，，： | 1 |
| 17 | Risk assessment for the development of hepatocellular carcinoma: According to on-treatment viral response during long-term lamivudine therapy in hepatitis B virus-related liver disease显示文摘 | Jong Ryul Eun Heon Ju Lee Tae Nyeun Kim Kyeung Soo Lee | 2010 | Journal of Hepatology2010，，1： | 1 |
| 18 | Exhaust Cleaning with Dielectric Barrier Discharge显示文摘To clean the exhaust emissions as one of the most important tasks in pollutioncontrol,a study on the treatment of engine emissions with discharge assistance was reported.ADBD plasma source shaped in grid and cylinder was examined in different engine operationalmodes to reduce the NO_x content of diesel engine exhaust.The composition of the exhaustgases and chemical reactions initiated by the discharge were analyzed.The discharge h'equencyhad a crucial impact on the device's performance and gas treatment.The voltages applied tothe discharge gap could alter the chemical reactions occurring in the treated gases,which wereindicated by the NO to NO_2 ratio.The operation of the system was studied at frequencies rangingfrom 400 Hz to 16 kHz. | Vadim Yu.PLAKSIN Oleksiy V.PENKOV Min Kook KO Heon Ju LEE | 2010 | Plasma Science and Technology2010，12，6： | 0 |
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