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112篇 您的检索式:作者名="Solit"
    题名 作者 年代 出处 被引量
1Pulsatile administration of the epidermal growth factor receptor inhibitor gefitinib is significantly more effective than continuous dosing for sentitizing tumors to paclitaxel显示文摘Solit DB She Y Lobe J 2005clin cancer Res2005,11,:1
2Development and application of Hsp90 inhibitors显示文摘Solit D B Chiosis G 2008Drug Discov Today2008,13,12:1
3New Efficient Synthesis of ResorcJnylic Macrolides via Ynolides: Establishment of Cycloproparadicicol as Synthetically Feasible Preclinical Anticancer Agent Based on Hsp90 as the Target 显示文摘YANG Z GENG X SOLIT D 2004J Am Chem Soc2004,126,:1
4KRAS and BRAF: drug targets and pre- dictive biomarkers显示文摘Vakiani E Solit D B 2011J Pathol2011,223,2:1
5In- hibition of heart shock protein in 90 function down-regulates Akt kinase and sensitizes tumors to taxol显示文摘Solit DB Basso AD Olshen AB 2003Cancer Res2003,62,9:1
6HsP90:a novel target for cancer therapy显示文摘Solit DB Rosen N 2006Curr Top Med Chem2006,6,11:1
7BRAF mutation predicts sensitivity to MEK inhibition 显示文摘Solit DB Garraway LA Pratilas CA 2006Nature2006,439,7074:1
8Akt forms an intracellular comJplex with heat shock Protein 90 (HSP90) and Cdc37 andis destabilized by Inhibitors of HSP90 funCtion 显示文摘Basso AD Solit DB Chiosis G 2002Biol Chem2002,277,39:1
9KRAS and BRAF:drug targets and predictive biomarkers显示文摘Vakiani E Solit DB 0,,02:1
10Inhibition of heat shock protein 90 function down-regulates Akt kinase and sensitizes tumors to Taxol显示文摘Solit D B Basso A D Olshen A B 2003Cancer Res2003,63,9:1
11Development and application oi Hsp90 inhibitors显示文摘Solit DB Chiosis G 2008Drug Discov Today2008,13,12:1
12Modulation of Hsp90 function by ansamycins sensitizes breast cance cells to chemotherapy-induced apoptosis in an RB-and schedule-dependent manner 显示文摘Munster PN Basso A Solit D 2001Clin Cancer Res2001,7,:1
13BRAF mutation predicts sensitivity to MEK inhibition 显示文摘SOLIT D B GARRAWAY L A PRATILAS C A 2005Nature2005,439,7074:1
14Inhibition of heat shock protein 90 function downregulatesAkt kinase and sensitizes tumors to Taxol 显示文摘Solit DB Basso AD Olshen AB 2003Cancer Res2003,63,:1
15A phase Ⅰ trial of intermittent high-dose gefitinib and fixed-dose docetaxel in patients with advanced solid tumors显示文摘Fury MG Solit DB Su YB 2007Cancer Chemother Pharmacol2007,59,:1
16Inhi- bition of heat shock protein 90 function down-regu- lates Akt kinase and sensitizes rumors to taxol 显示文摘SOLIT D B BASSO A D OLSHEN A B 2003Cancer Res2003,63,9:1
17KRAS and BRAF: drug targets and predictive biomarkers 显示文摘Vakiani E Solit DB 2011J Pathol2011,223,2:1
18Inhibition of heat shock protein 90 function down-regnlates Akt kinase and sensitizes tumors to Taxol显示文摘 Basso AD Olshen AB 2003Cancer Res2003,63,9:1
19T he BAD protein integrates survival signaling by egfr/mapk and PI 3 K/akt kinase pathways in pten-deficient tumor ceils 显示文摘She QB Solit DB Ye Q 2005Cancer Cell2005,8,4:1
20Angiosperm phylogeny inferred from 18s rDNA,rbcL and atpB sequences显示文摘Solits DE Solits PS Chase MW 2000 2000Bot J Linn Soc2000,133,:1
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