|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Current advances in using tolerogenic dendritic cells as a therapeutic alternative in the treatment of type 1 diabetes显示文摘Type 1 diabetes(T1D)is an autoimmune disease characterized by the destruction of insulin-producingβ-cells of the pancreatic islets by autoreactive T cells,leading to high blood glucose levels and severe long-term complications.The typical treatment indicated in T1D is exogenous insulin administration,which controls glucose levels;however,it does not stop the autoimmune process.Various strategies have been implemented aimed at stoppingβ-cell destruction,such as cellular therapy.Dendritic cells(DCs)as an alternative in cellular therapy have gained great interest for autoimmune disease therapy due to their plasticity to acquire immunoregulatory properties both in vivo and in vitro,performing functions such as anti-inflammatory cytokine secretion and suppression of autoreactive lymphocytes,which are dependent of their tolerogenic phenotype,displayed by features such as semimature phenotype,low surface expression of stimulatory molecules to prime T cells,as well as the elevated expression of inhibitory markers.DCs may be obtained and propagated easily in optimal amounts from peripheral blood or bone marrow precursors,such as monocytes or hematopoietic stem cells,respectively;therefore,various protocols have been established for tolerogenic(tol)DCs manufacturing for therapeutic research in the treatment of T1D.In this review,we address the current advances in the use of tolDCs for T1D therapy,encompassing protocols for their manufacturing,the data obtained from preclinical studies carried out,and the status of clinical research evaluating the safety,feasibility,and effectiveness of tolDCs. | William de Jesús Ríos-Ríos Sorely Adelina Sosa-Luis Honorio Torres-Aguilar | 2021 | World Journal of Diabetes2021，12，5： | 2 |
| 2 | Film condensation in presence of non-condensable gases over horizontal tubes with progressively increasing radius of curvature in the direction of gravity 显示文摘 | Sore S K Chakraborty S | 2006 | International Journal of Heat and Mass Transfer2006，49，： | 1 |
| 3 | Infuences of spray and operating parameters on penetration of vaporizing fuei droplets in a gas tur- bine eombustor 显示文摘 | Sharma N Y K A D Sore S K | 2001 | Applied Thermal Engineering2001，21，： | 1 |
| 4 | Coefficient of dischrage and spray cone angle of a pressure nozzle with combined axial and tangential entry of power-law fluids 显示文摘 | Biswas G Sore S K | 1986 | Applied Scienti- fic Research1986，43，： | 1 |
| 5 | Numerical predictions on the influences of the air blast velocity, initial bed porosity and bed height on the shape and size of raceway zone in a blast turnace显示文摘 | Mondal S S Sore S K | 2005 | Journal of Physics D : Applied Pbysics2005，38，： | 1 |
| 6 | Influence of implantation induced Ni- doping on struetural, optieal, and morphologieal proper- ties of nanoerystalline CdS thin films 显示文摘 | Chandramohan S Straehe T Sarangi S N Sathyamoor- thy R Sore T | 2010 | Materials Sei- enee and Engineering B-Advaneed Functional Solid-State Materials2010，171，13： | 1 |
| 7 | Urinary uric acid in preterm neonates显示文摘 | Basu P Sore S Choudhuri N | 2009 | Indian J Pediatr2009，76，： | 1 |
| 8 | Inflammatatory pseudotumor of the maxillary sinus: CT and MR findings in six cases 显示文摘 | Sore P M Brandwein M S Maldjian C | 1994 | Am J Roentgenol1994，163，3： | 1 |
| 9 | Fast and digitally wavelength-tunable semiconductor ring laser using a monolithically integrated distributed Bragg reflector显示文摘 | Furst S Yu S Sore Ml | 2008 | IEEE Photon Technol Lett2008，20，23： | 1 |
| 10 | Advances in the pharmacotherapy of Alzheimer' s disease 显示文摘 | SORES J C GERSHON S | 1994 | Eur Arch of Psych Clini Neurosci1994，245，5： | 1 |
| 11 | A comparison of injector flow and spray characteristics of biodiesel with petrodiesel显示文摘 | Sore S Longman D E Ramrez A I | 2010 | Fu- el2010，89，12： | 1 |
| 12 | Numerical prediction of air core diameter, coefficient of discharge and spray cone angle of a swirl pressure nozzle显示文摘 | Datta A Sore S K | 2000 | International Journal of Heat and Fluid Flow2000，21，4： | 1 |
| 13 | Dopaminergic role in stimulant-induced waken fullness显示文摘 | Wisor JP Nishino S Sore L | 2001 | J Neurosci2001，21，5： | 1 |
| 14 | Phototargeting oral black-pigmented bacteria 显示文摘 | Soukos NS Sore S Abernethy AD | 2005 | Antimicrob Agents Chemother2005，49，4： | 1 |
| 15 | Effect of nozzle orifice geometry on spray, combustion, and emission characteristics under diesel engine conditions显示文摘 | Sore S Ramirez A I Longman D E | 2011 | Fuel2011，90，3： | 1 |
| 16 | Effects of primary breakup modeling on spray and combustion characteristics of compression ignition engines显示文摘 | Sore S Aggarwal S K | 2010 | Combustion and Flame2010，157，6： | 1 |
| 17 | Impact of Foreign Direct Investment and Frade on Economic Growth :Evidence from Developing Countries 显示文摘 | M akki Shiva S Agapi Sore waru | 2004 | American Agricultural Economics Association2004，，86： | 1 |
| 18 | Dopaminergic role in stimulatnt -induced wakenfulness显示文摘 | Wisor JP Nishino S Sore 1 | 2001 | J Nerrosci2001，21，5： | 1 |
| 19 | Phototargeting oral black-pigmented bacteria 显示文摘 | Soukos NS Sore S Abemethy AD | 2005 | Antimicrob Agents Chemother2005，49，： | 1 |
| 20 | Comparison of strained SiGe heterostructure-on-insulator (001) and (110) PMOSFETs: C-V characteristics, mobility, and ON current 显示文摘 | PHAM A T ZHAO Q T JUNGEMANN C MEINERZHAGEN B MANTL S SOREE B POURTOLS G | 2011 | Solid-State Electronics2011，6566，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员