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| 1 | Large endoscopic mucosal resection for colorectal tumors exceeding 4 cm显示文摘AIM:To evaluate the feasibility and the outcome of endoscopic mucosal resection(EMR)for large colorectal tumors exceeding 4 cm(LCRT)undergoing piecemeal resection. METHODS:From January 2005 to April 2008,146 digestive tumors larger than 2 cm were removed with the EMR technique in our department.Of these,34 tumors were larger than 4 cm and piecemeal resection was carried out on 26 colorectal tumors.The mean age of the patients was 71 years.The mean follow-up duration was 12 mo. RESULTS:LCRTs were located in the rectum,left colon,transverse colon and right colon in 58%,15%, 4%and 23%of cases,respectively.All were sessile tumors larger than 4 cm with a mean size of 4.9 cm (4-10 cm).According to the Paris classification,34%of the tumors were typeⅠs,58%typeⅡa,4%typeⅡb and 4%typeⅡc.Pathological examination showed tubulous adenoma in 31%,tubulo-villous adenoma in 27%,villous adenoma in 42%,high-grade dysplasia in38%,in situ carcinoma in 19%of the cases and mucosal carcinoma(m2)in 8%of the cases.The two cases(7.7%)of procedural bleeding that occurred were managed endoscopically and one small perforation was treated with clips.During follow-up,recurrence of the tumor occurred in three patients(12%),three of whom received endoscopic treatment. CONCLUSION:EMR for tumors larger than 4 cm is a safe and effective procedure that could compete with endoscopic submucosal dissection,despite providing incomplete histological assessment. | Philippe Ah Soune Charles Ménard Ezzedine Salah Ariadne Desjeux Jean-Charles Grimaud Marc Barthet | 2010 | World Journal of Gastroenterology2010，16，5： | 4 |
| 2 | Nonprofits as Local Government Service Contractors显示文摘 | FEIOCK R C SOUN J H | 2009 | Public Administration Review2009，69，4： | 1 |
| 3 | Increase of xylitol productivity by cell-recycle fermentation of Candida Tropicalis using submerged membrane bioreactor 显示文摘 | Soun - Gyu Kwon Seung - Won Park Deok - Kun Oh | 2006 | Journal of Bioscience and Bioengineering2006，101，1： | 1 |
| 4 | Pharming and transgenic plants显示文摘 | Lie'nard D Soun'ouille C Gomord V | 2007 | Biotechnology Annual Review2007，13，： | 1 |
| 5 | Reciprocal control of T helper cell and dendritic cell differentiation显示文摘 | Sounelis V Kadowaki N | 1999 | Science1999，283，5405： | 1 |
| 6 | Aerosol optical properties over east Asia determined from ground-based sky radiation measurements显示文摘 | KIM D SOUN B NAKAJIMA T | 2004 | J Geophys Res2004，109，2： | 1 |
| 7 | Renal Biopsy in zhe elderly显示文摘 | Modesto Segonds AM Ah Soune MF Durand D | 1993 | Am J Nephorl1993，13，1： | 1 |
| 8 | Increase ofxylitol productivity by cell-recycle fermentation of Candida tropicalis using submerged membrane bioreactor 显示文摘 | Kwon Soun Gyu Park Seung Won Oh Deok Kun | 2006 | Journal of Bioscience and Bioengineering2006，101，1： | 1 |
| 9 | Opioids in the hypothalamic paraventricular nucleus stimulate ethanol intake显示文摘 | Barson J R Carr A J Soun J | 2010 | Alcoholism2010，34，2： | 1 |
| 10 | Fostering social innovation and building adaptive capacity for dengue control in Cambodia: a case study显示文摘Background:The social-ecological systems theory,with its unique conception of resilience(social-ecological systems&resilience,SESR),provides an operational framework that currently best meets the need for integration and adaptive governance as encouraged by the Sustainable Development Goals.SESR accounts for the complex dynamics of social-ecological systems and operationalizes transdisciplinarity by focusing on community engagement,value co-creation,decentralized leadership and social innovation.Targeting Social Innovation(SI)in the context of implementation research for vector-borne diseases(VBD)control offers a low-cost strategy to contribute to lasting and contextualized community engagement in disease control and health development in low and middle income countries of the global south.In this article we describe the processes of community engagement and transdisciplinary collaboration underpinning community-based dengue management in rural primary schools and households in two districts in Cambodia.Methods:Multiple student-led and community-based interventions have been implemented focusing on empowering education,communication for behavioral change and participatory epidemiology mapping in order to engage Cambodian communities in dengue control.We describe in particular the significance of the participatory processes that have contributed to the design of SI products that emerged following iterative consultations with community stakeholders to address the dengue problem.Results:The SI products that emerged following our interaction with community members are 1)adult mosquito traps made locally from solid waste collections,2)revised dengue curriculum with hands-on activities for transformative learning,3)guppy distribution systems led by community members,4)co-design of dengue prevention communication material by students and community members,5)community mapping.Conclusions:The initiative described in this article put in motion processes of community engagement towards creating ownership of dengue control interventions tools by community stakeholders,including school children.While the project is ongoing,the project's interventions so far implemented have contributed to the emergence of culturally relevant SI products and provided initial clues regarding 1)the conditions allowing SI to emerge,2)specific mechanisms by which it happens and 3)how external parties can facilitate SI emergence.Overall there seems to be a strong argument to be made in supporting SI as a desirable outcome of project implementation towards building adaptive capacity and resilience and to use the protocol supporting this project implementation as an operational guiding document for other VBD adaptive management in the region. | Pierre Echaubard Chea Thy Soun Sokha Set Srun Claudia Nieto-Sanchez Koen Peters Grietens Noel R.Juban Jana Mier-Alpano Sucelle Deacosta Mojgan Sami Leo Braack Bernadette Ramirez Jeffrey Hii | 2020 | Infectious Diseases of Poverty2020，9，5： | 0 |
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