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| 1 | Use of albendazole sulfoxide, albendazole sulfone, and combined solutions as scolicidal agents on hydatid cysts (in vitro study)显示文摘AIM: To establish which scolicidal agents are superiorand more suitable for regular use.METHODS: Echinococcus granulosus protoscoleceswere obtained from 25 patients with liver hydatidcysts. Various concentrations of albendazole sulfone,albendazole sulfoxide, and albendazole sulfone andalbendazole sulfoxide mixed together in concentrationsof 50 μg/mL, and H2O2 in a concentration of 4%, NaCl20%, and 1.5% cetrimide-0.15% chlorhexidine (10%Savlon-Turkey) were used to determine the scolicidaleffects. Albendazole (ABZ) derivatives and otherscolicidal agents were applied to a minimum of 100scoleces for 5 and 10 min. The degree of viability wascalculated according to the number of living scolicesper fi eld from a total of 100 scolices observed underthe microscope.RESULTS: After 5 min, ABZ sulfone was 97.3%effective, ABZ sulfoxide was 98.4% effective, and thecombined solution was 98.6% effective. When sulfone,sulfoxide and the combined solutions were compared,the combined solution seemed more effective thansulfone. However, there was no difference when thecombined solution was compared with sulfoxide. After10 min, hypertonic salt water, sulfone, sulfoxide, andthe combined solution compared to other solutionslooked more effective and this was statisticallysignificant on an advanced level. When sulfone,sulfoxide, and the combined solutions were compared with each other, the combined solution appeared more effective than sulfone. When the combined solution was compared with sulfoxide, there was no difference.CONCLUSION: Despite being active, ABZ metabolites did not provide a marked advantage over 20% hypertonic saline. According to these results, we think creating a newly improved and more active preparation is necessary for hydatid cyst treatment. | Gokhan Adas Soykan Arikan Ozgur Kemik Ali Oner Nilgun Sahip Oguzhan Karatepe | 2009 | World Journal of Gastroenterology2009，15，1： | 19 |
| 2 | Cisapride in the long termtreatment of chronic gastroparesis: a 22year label study 显示文摘 | Kendall BJ Kendall ET Soykan I | 1997 | Int MedRes1997，25，4： | 1 |
| 3 | Demography, clinical characteristics, psychological and abuse profiles, treatment, and long-term followup of patients with gastroparesis显示文摘 | Soykan I Sivri B Sarosiek I | 1998 | Dig Dis Sci1998，43，： | 1 |
| 4 | 显示文摘 | Eric R H King R P | 1991 | Met Trans B1991，22，6： | 1 |
| 5 | Microstructure,Mechanical and Thermal Properties of Boron Oxide Added SteatiteCeramics显示文摘 | Soykan H S Aslanoglu Z Karakas Y | 2006 | Advances in Applied Ceramics2006，105，6： | 1 |
| 6 | Psychometric properties of the Hamilton Depression Rating Scale and other physician-rated psychiatric scales for the assessment of depression in ESRD patients undergoing hemodialysis in Turkey显示文摘 | GENCZ F GENCZ T SOYKAN A | 2007 | Psychology Health & Medicine2007，12，4： | 1 |
| 7 | Demography,Clinical characteristics,psychological and abuse profiles,treatment, and long-term follow-up of patients with gastroparesis显示文摘 | I Soykan B Sivri I Sarosiek | 1998 | Dig Dis Sci1998，43，11： | 1 |
| 8 | Abdominal wall endometriosis:a diagnositic dilemma for surgeons显示文摘 | Ahmet K Esra A Soykan A | 2005 | Med Princ Pract2005，14，6： | 1 |
| 9 | Demography, Clinical Characteristics, Psychological and Abuse Profiles, Treatment, and Long-Term Follow-up of Patients with Gastroparesis显示文摘 | Irfan Soykan Bulent Sivri Irene Sarosiek Brian Kiernan Richard W. Mccallum | 1998 | Digestive Diseases and Sciences1998，，11： | 1 |
| 10 | Domperidone:review of pharmacology and clinical applications in gastroenterology显示文摘 | Reddymasu SC Soykan I McCallum RW | 2007 | Am J Gastroenterol2007，102，20： | 1 |
| 11 | Gastric myoelectrical activity in patients with Parkinson' s disease:evidence of a primary gastric abnormality 显示文摘 | Soykan I Lin Z Bennett J P | 1999 | Dig Dis Sci1999，44，5： | 1 |
| 12 | Minimal extracorpo- real circulation (MECC) does riot result in less hypertrophic scar formation as compared to conventional extracorporeal circulation (CECC) with dexamethasone 显示文摘 | Soykan EA Butzelaar L de Kroon TL | 2014 | Perfusion2014，29，3： | 1 |
| 13 | Abdominal wall endometriosis:a diagnositic dilemma for surgeons显示文摘 | Athmet K Esna A Soykan A | 2005 | Med Princ Pract2005，14，6： | 1 |
| 14 | Cisapride in the long - term treatment of chronic gastroparesis: a 2 - year open - label study 显示文摘 | KENDALL B J KENDALL ET SOYKAN I | 1997 | J Int Med Res1997，25，： | 1 |
| 15 | Gastric myoelectrical activity, gastric emptying and correlations with dyspepsia symptoms in patients with gastroesophageal reflux显示文摘 | SOYKAN I LIN Z JONES S | 1997 | Journal of Investigative Medicine1997，45，8： | 1 |
| 16 | Cisapride in the long-term treatment of chronic gastroparesis: A2-year open-label study 显示文摘 | Kendall BJ Kendall ET Soykan I | 2007 | J Int Med Res2007，25，4： | 1 |
| 17 | Barrett's esophagus: prevalence and its relationship with dyspeptic symptoms 显示文摘 | Toruner M Soykan I Ensari A | 2004 | J Gastroenterol Hepatol2004，19，5： | 1 |
| 18 | The effect of chronic oral domperidone therapy on gastrointestinal symptoms,gastric emptying,and quality of life in patients with gastroparesis显示文摘 | Soykan I Sarosiek 1 McCallum RW | 1997 | Am J Gastroenterol1997，92，6： | 1 |
| 19 | Serum vitamin B 12 and folate status in patients with inflammatory bowel diseases显示文摘 | Mustafa Yakut Yusuf üstün G?khan Kaba?am Irfan Soykan | 2010 | European Journal of Internal Medicine2010，，4： | 1 |
| 20 | Gastric myoelectricalactivity in patients with parkinson's disease: evidence of a primary gastric abnormality显示文摘 | Soykan I Lin Z Bennett J P | 1999 | Dig Dis Sci1999，44，5： | 1 |
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