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| 1 | Chemokine and chemotactic signals in dendritic cell migration显示文摘Dendritic cells (DCs) are professional antigen-presenting cells responsible for the activation of specific T-cell responses and for thedevelopment of immune tolerance. Immature DCs reside in peripheral tissues and specialize in antigen capture, whereas matureDCs reside mostly in the secondary lymphoid organs where they act as antigen-presenting cells. The correct localization of DCs isstrictly regulated by a large variety of chemotactic and nonchemotactic signals that include bacterial products, DAMPs (dangerassociated molecular patterns), complement proteins, lipids, and chemokines. These signals function both individually and inconcert, generating a complex regulatory network. This network is regulated at multiple levels through different strategies, such assynergistic interactions, proteolytic processing, and the actions of atypical chemokine receptors. Understanding this complexscenario will help to clarify the role of DCs in different pathological conditions, such as autoimmune diseases and cancers and willuncover new molecular targets for therapeutic interventions. | Laura Tiberio Annalisa Del Prete Tiziana Schioppa Francesca Sozio Daniela Bosisio Silvano Sozzani | 2018 | Cellular & Molecular Immunology2018，15，4： | 14 |
| 2 | Cooling dialysate during in-center hemodialysis:Beneficial and deleterious effects显示文摘The use of cooled dialysate temperatures first came about in the early 1980 s as a way to curb the incidence of intradialytic hypotension(IDH). IDH was then, and it remains today, the most common complication affecting chronic hemodialysis patients. It decreases quality of life on dialysis and is an independent risk factor for mortality. Cooling dialysate was first employed as a technique to incite peripheral vasoconstriction on dialysis and in turn reduce the incidence of intradialytic hypotension. Although it has become a common practice amongst incenter hemodialysis units, cooled dialysate results in up to 70% of patients feeling cold while on dialysis and some even experience shivering. Over the years, various studies have been performed to evaluate the safety and efficacy of cooled dialysate in comparison to a standard, more thermoneutral dialysate temperature of 37 ℃. Although these studies are limited by small sample size, they are promising in many aspects. They demonstrated that cooled dialysis is safe and equally efficacious as thermoneutral dialysis. Although patients report feeling cold on dialysis, they also report increased energy and an improvement in their overall health following cooled dialysis. They established that cooling dialysate temperatures improves hemodynamic tolerability during and after hemodialysis, even in patients prone to IDH, and does so without adversely affecting dialysis adequacy. Cooled dialysis also reduces the incidence of IDH and has a protective effect over major organs including the heart and brain. Finally, it is an inexpensive measure that decreases economic burden by reducing necessary nursing intervention for issues that arise on hemodialysis such as IDH. Before cooled dialysate becomes standard of care for patients on chronic hemodialysis, larger studies with longer follow-up periods will need to take place to confirm the encouraging outcomes mentioned here. | Stephanie M Toth-Manikowski Stephen M Sozio | 2016 | World Journal of Nephrology2016，5，2： | 14 |
| 3 | The Role of Lipid Metabolism in the Pathogenesis of Alcoholic and Nonalcoholic Hepatic Steatosis显示文摘 | Margaret Sozio Suthat Liangpunsakul David Crabb | 2010 | Semin Liver Dis2010，，04： | 2 |
| 4 | The shrink-free ceramic crown显示文摘 | Riley EJ | 1983 | J Prosthet Dent1983，49，： | 1 |
| 5 | Morphometric analysis of intralobular,interlobular and pleural lymphatics in normal human lung显示文摘 | Sozio F Rossi A Weber E | 2012 | J Anat2012，220，4： | 1 |
| 6 | Troponin I and NT-proBNP and the association of systolic blood pressure with outcomes in incident hemodialysis patients:the Choices for Healthy Outcomes in Caring for ESRD(CHOICE) Study显示文摘 | Shaft T Zager PG Sozio SM | 2014 | Am J Kidney Dis2014，64，3： | 1 |
| 7 | Social content matching in MapReduce 显示文摘 | DE FRANCISCI MORALES G GIONIS A SOZIO M | 2011 | Proceedings of the VLDB endowment2011，4，7： | 1 |
| 8 | The role of lipid me- tabolism in the pathogenesis of alcoholic and nonalcoholic hepatic steatosis 显示文摘 | Sozio MS Liangpunsakul S Crabb D | 2010 | Semin Liver Dis2010，30，： | 1 |
| 9 | Digestive hemorrhages of obscure origin显示文摘 | Tficarico A Cione G Sozio M | 2002 | Surg Endosc2002，16，4： | 1 |
| 10 | Ibuprofen and glutathione conjugate as a potential therapeu- tic agent for treating Alzheimer's disease显示文摘 | Pinnen F Sozio P Cacciatore I | 2011 | Arch Pharm (Weinheim)2011，344，3： | 1 |
| 11 | The role of lipid metabolism in the pathogenesis of aleoholic and nonalcoholic hepatic stcatosis 显示文摘 | Sozio MS Liangpunsakul S Crabb D | 2010 | Semin Liver Dis2010，30，4： | 1 |
| 12 | Focus on the prophylaxis, epidemiology and therapy of methicillin-resistant Staphylo coccus aureus surgical site infections and a position paper on associated risk factors: the perspective of an Italian group of surgeons显示文摘 | Sganga G Tascini C Sozio E | 2016 | World J Emerg Surg2016，6，14： | 1 |
| 13 | Endolaparoscopic rendezvous treatment:a satisfying therapeutic choice for cholecystochole- docolithiasis显示文摘 | Tricarico A Cione G Sozio M | 2002 | Surg Endosc2002，16，4： | 1 |
| 14 | Lymphatic and blood vessels in scleroderma skin,a morphometric analysis显示文摘 | Rossi A Sozio F Sestini P | 2010 | Hum Pathol2010，41，3： | 1 |
| 15 | L-dopa prodrugs: an overview of trends for improving Parkinson' s disease treatment 显示文摘 | Di Stefano A Sozio P Cerasa L S | 2011 | Curr Pharm Des2011，17，32： | 1 |
| 16 | Digestive hemorrhages of obscure origin显示文摘 | Tricarico A Cione G Sozio M | | 0，，04： | 1 |
| 17 | Inhibitory effect of ethanol on AMPK phosphorylation is mediated in part through elevated ceramide levels显示文摘 | Liangpunsakul S Sozio MS Shin E | 2010 | Am J Physiol Gastrointest Liver Physiol2010，298，： | 1 |
| 18 | Gastric metastases of breast carcinoma显示文摘 | Amicucci G Sozio ML Szio A | 1999 | Am J Gastroenterol1999，94，3： | 1 |
| 19 | Inhibitory effect of ethanol on AMPK phosphorylation is mediated in part through elevated ceramide levels 显示文摘 | Liangpunsakul S Sozio MS Shin E | 2010 | Am J Physiol Gastrointest Liver Physiol2010，298，6： | 1 |
| 20 | Endolaparoscopic rendez- vous treatment: asaisfyingtherapertic choice forcholecystochole- docolithiasis显示文摘 | Tricarico A Cicone G Sozio M | 2012 | Surg Endose2012，16，4： | 1 |
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