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52篇 您的检索式:作者名="Spehner"
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1Severe COVID-19 patients exhibit an ILC2 NKG2D^(+) population in their impaired ILC compartment显示文摘Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is responsible for the current COVID-19 disease pandemic.In some patients,the symptoms are mild,and a fraction of SARS-CoV-2-infected individuals develop severe illness with a high fatality rate due to lung damage and acute respiratory distress syndrome.1 Innate lymphoid cells(ILCs)are a recently identified type of effector immune cells that rapidly sense environmental stimuli and participate in early immune responses by promptly secreting large amounts of cytokines.2 The ILC2 subpopulation was shown to mediate Type 2 responses and to recruit eosinophils during viral lung infections upon the release of alarmins(e.g.,IL-33)by damaged epithelial cells.3,4,5 ILC2s were also shown to participate in the termination of inflammatory responses and tissue repair by amphiregulin secretion.In addition,ILC2s are critical in the early phases of allergic lung inflammation,including that induced by the protease allergen papain.6 Based on the essential function of the papain-like protease PLpro in regulating SARS-CoV-27(Fig.1a)and the severe lung damage caused by this virus,we sought to investigate the potential involvement of ILC2s in immune responses to COVID-19.Alejandra Gomez-Cadena Laurie Spehner Marie Kroemer Myriam Ben Khelil Kevin Bouiller Grégory Verdeil Sara Trabanelli Christophe Borg Romain Loyon Camilla Jandus 2021Cellular & Molecular Immunology2021,18,2:2
2Assembly of nucleocapsidlike structures in animal cells infected with a vaccinia virus recombinant encoding the measles virus nucleoprotein 显示文摘Spehner D Kirn A Drillien R 1991J Virol1991,65,:1
3The conserved N-terminal region of Sendai virus nucleocapsid protein NP is required for nualeocapsid assembly显示文摘Bucholz CJ Spehner D Drillien R 1993J Virology1993,67,10:1
4Cutting edge receptor-medi-ated endocytosis of heat shock proteins by professional antigen-presenting cell显示文摘 Hanau D Spehner D 1999J Immunol1999,162,7:1
5Heat shock proteins 70 and 60 share common receptors which are expressed on human monocyte-derived but not epidermal dendritic cells显示文摘Lipsker D Ziylan U Spehner D 2002Eur J Immunol2002,32,2:1
6Localization and sequence of a vaccinia virus gene required for multiplication in human cells显示文摘GILLARD S SPEHNER D DRILLIEN R 1986Proc Natl Acad Sci USA1986,83,15:1
7Alleration in the production of free oxygen radicals and proinflammatory cytokines by peritoneal and alveolar macrophages in old mice and immunomodulatory effect of RU 41740 administration Part I: Effect of short and repetitive noise stress 显示文摘de Wazieres B Spehner V Harraga S 1998hnmunop- harmacology1998,39,1:1
8Reduced surface: an efficient way to compute molecular surfaces 显示文摘Sanner M F Olson A J Spehner J C 1996Biopolymers1996,38,3:1
9Cutting edge: receptor- mediated endocytosis of heat shock proteins by professional antigen- presenting cells显示文摘Arnold-Schild D Hanau D Spehner D 1999J Immunol1999,162,7:1
10Cutting edge: Receptor-mediated endocytosis of heat shock proteins by professional antigen-presenting cells显示文摘 Hanau D Spehner D 1999J Immunol1999,162,:1
11Antibodies di- rected against a synthetic peptide enable detection of a protein encoded by a vaccinia virus host range gene that is conserved within the Orthopoxvirus genus显示文摘Gillard S Spehner D Drillien R 1989J Vir- ol1989,63,4:1
12Cutting edge: receptor-medi-ated endocytosis of heat shock proteins by professional antigen-pre-senting cells显示文摘Arnold Schild D Hanan D Spehner D 1999J Immunol1999,162,7:1
13The conserved N-terminal region of Sendal virus nucleocapsid protein NP is required for nucleocapsid assembly 显示文摘Buchholz C J Spehner D Drillien R 1993J Virol1993,67,10:1
14Role of sulfatide in vac- cinia virus infection显示文摘Perino J Foo C H Spehner D 2011Biol Cell2011,103,7:1
15Reduced surface: an efficient way to compute molecular surfaces 显示文摘SANNER M F OLSON A J SPEHNER J C 1996Biopolymers1996,38,3:1
16Heat shock proteins 70 and 60 share common receptors which are expressed on human monocyte-derived but not epidermal dendritic cells 显示文摘Lipsker D Ziylan U Spehner D Proamer F 2002Eur J Immunol2002,32,2:1
17Cutting edge:receptor-mediated endocytosis of heat shock proteins byprofessional antigen-presenting cells显示文摘Arnold-Schild D Hanau D Spehner D 1999J Immunol1999,162,:1
18Alteration in the production of free oxygen radicals and proinflammatory cytokines by peritoneal and alveolar macrophages in old mice and immunomodulatory effect of RU 41740 administration Part I:Effect of short and repetitive noise stress显示文摘de Wazieres B Spehner V Harraga S 0,,01:1
19Birbeck granules are subdomains of endosomal recycling compartment in human epidermal Langerhans cells,which form where Langerin accumulates显示文摘Mc Dermott R Ziylan U Spehner D 0,,01:1
20Noise in Bose Josephson junctions: Decoherence and phase relaxation 显示文摘Ferrini G Spehner D Minguzzi A 2010Phys Rev A2010,82,03:1
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