|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Predictive factors of survival in patients treated with definitive chemoradiotherapy for squamous cell esophageal carcinoma显示文摘瞄准:学习的目的是与食道的癌(LASCOC ) 与权威的 chemoradiotherapy (CRT ) 对待的局部地先进的有鳞的房间在病人评估幸存的预兆的因素政体基于 5FU/CDDP 联合。方法:有用在 1994 和 2000 之间的 5FU/CDDP 联合与权威的 CRT 对待的 LASCOC 的所有病人回顾地被包括。对 CRT 的临床的完全的反应(CCR ) 被食道的内视镜检查法和 CT 扫描估计在 CRT 结束以后的 2 瞬间。幸存的预示的因素用 univariate 被估计,多,由艇长回归的变量分析当模特儿。结果:116 个病人的一个总数在学习被包括。到 CRT 的 CCR 在 86/116 (74.1%) 被观察。中部的幸存是 20 瞬间(范围 2-114 ) , 5 年的幸存是 9.4% 。到 CRT 的应答者病人的中部的幸存在非应答者病人作为与 9 瞬间(范围 2-81 ) 相比是 25 瞬间(范围 3-114 )(P <
0.001 ) 。在 univariate 分析,幸存与 CCR 被联系(P <
0.001 ) ,表演地位 <
2 (P = 0.01 ) ,瘤长度 <
6 厘米(P = 0.045 ) 并且 10% 在意义的限制的重量损失 <
(P = 0.053 ) 。在里面多变量分析,幸存对 CCR 依赖(P <
0.0001 ) ,重量损失 <
10%(P = 0.034 ) 并且表演 <
2 (P = 0.046 ) 。结论:我们的结果建议在有与权威的 CRT 对待的 LASCOC 的病人的那幸存被相关到 CCR,重量损失并且表演地位。 | Frédéric Di Fiore Stéphane Lecleire Olivier Rigal Marie-Pierre Galais Emmanuel Ben Soussan Isabelle David Bernard Paillot Jacques-Henri Jacob Pierre Michel | 2006 | World Journal of Gastroenterology2006，12，26： | 13 |
| 2 | Increased Risk for Nonmelanoma Skin Cancers in Patients Who Receive Thiopurines for Inflammatory Bowel Disease显示文摘 | Laurent Peyrin–Biroulet Kiarash Khosrotehrani Fabrice Carrat Anne–Marie Bouvier Jean–Baptiste Chevaux Tabassome Simon Frank Carbonnel Jean–Frédéric Colombel Jean–Louis Dupas Philippe Godeberge Jean–Pierre Hugot Marc Lémann Stéphane Nahon Jean–Marc Sabaté | 2011 | Gastroenterology2011，，5： | 3 |
| 3 | Endoscopy-based management decreases the risk of postoperative recurrences in Crohn's disease显示文摘AIM: To investigate whether an endoscopy-based management could prevent the long-term risk of postoperative recurrence.METHODS: From the pathology department database, we retrospectively retrieved the data of all the patients operated on for Crohn's disease(CD) in our center(1986-2015). Endoscopy-based management was defined as systematic postoperative colonoscopy(median time after surgery = 9.5 mo) in patients with no clinical postoperative recurrence at the time of endoscopy. RESULTS: From 205 patients who underwent surgery, 161 patients(follow-up > 6 mo) were included. Endoscopic postoperative recurrence occurred in 67.6%, 79.7%, and 95.5% of the patients, respectively 5, 10 and 20 years after surgery. The rate of clinical postoperative recurrence was 61.4%, 75.9%, and 92.5% at 5, 10 and 20 years, respectively. The rate of surgical postoperative recurrence was 19.0%, 38.9% and 64.7%, respectively, 5, 10 and 20 years after surgery. In multivariate analysis, previous intestinal resection, prior exposure to anti-TNF therapy before surgery, and fistulizing phenotype(B3) were postoperative risk factors. Previous perianal abscess/fistula(other perianal lesions excluded), were predictive of only symptomatic recurrence. In multivariate analysis, an endoscopy-based management(n = 49/161) prevented clinical(HR = 0.4, 95%CI: 0.25-0.66, P < 0.001) and surgical postoperative recurrence(HR = 0.30, 95%CI: 0.13-0.70, P = 0.006).CONCLUSION: Endoscopy-based management should be recommended in all CD patients within the first year after surgery as it highly decreases the long-term risk of clinical recurrence and reoperation. | Anne-Laure Boucher Bruno Pereira Stéphanie Decousus Marion Goutte Felix Goutorbe Anne Dubois Johan Gagniere Corinne Borderon Juliette Joubert Denis Pezet Michel Dapoigny Pierre J Déchelotte Gilles Bommelaer Anthony Buisson | 2016 | World Journal of Gastroenterology2016，22，21： | 3 |
| 4 | Duodenal intraepithelial T lymphocytes in patients with functional dyspepsia显示文摘AIM: To quantify the intraepithelial lymphocytes (IELs) and to document the membrane expression of CD4, CD8, TCRγδ and adhesion and/or activation-associated molecules (CD103, CD28, CD44, CD69, HLA-DR, CD95/ Fas) in the duodenal mucosa of patients with functional dyspepsia (FD) in order to provide arguments for an immunological process in FD. METHODS: Twenty-six FD patients according to Rome Ⅱ criteria (20 were H pylori negative) were studied and compared to 12 healthy adults. IELs were isolated from five duodenal biopsy samples, then quantified by microscopy and flow cytometry while the membrane phenotypes were determined by cytofluorometry. RESULTS: Duodenal histological examination was normal. In H pylori negative patients, the number of IELs was not different from that in healthy controls. Median percentage expression of CD4, CD8, or TCRγδ and CD103, CD44, CD28, CD69 on CD3+ IELs, among the adhesion/activation associated molecules tested, was not different from that in healthy controls. In contrast, the median percentage expression of CD95/ Fas [22 (9-65) vs 45 (19-88), P = 0.03] and HLA- DR expressing CD3+ IELs [4 (0-30) vs 13 (4-42), P = 0.04] was significantly lower in the H pylori negative FD group than in healthy controls, respectively. The number of IELs was significantly greater in H pylori positive FD patients than in healthy controls [median ratiofor 100 enterocytes 27.5 (6.7-62.5) vs 10.8 (3-33.3), P = 0.02] due to a higher number of CD8+ CD3+ IELs. CONCLUSION: In H pylori negative FD patients, the phenotypic characterization of IELs suggests that we cannot exclude a role of IELs in FD. | Gilles Gargala Stéphane Lecleire Arnaud Franois Serge Jacquot Pierre Déchelotte Jean Jacques Ballet Loic Favennec Philippe Ducrotté | 2007 | World Journal of Gastroenterology2007，13，16： | 2 |
| 5 | Stlucture- borne noise reduction in a truck cab interior using nu- merical techniques 显示文摘 | Mohanty A R St Pierre B D Suruli N P | 2000 | Applied Acoustics2000，59，1： | 1 |
| 6 | Structure-borne noise reduction in a truck cab interior using numerical techniques显示文摘 | Mohanty Amiya R St Pierre Barry D Suruli- Narayanasami P | 2000 | Applied Acoustics2000，59，1： | 1 |
| 7 | Structure-borne noise reduction in a truck cab interior using numerical techniques 显示文摘 | Amiya R Mohanty Barry D St Pierre P Suruli Narayanasami | 2000 | Applied Acoustics2000，117，： | 1 |
| 8 | Prognostic factors in women treated for ovarian yolk sac tumour: A retrospective analysis of 84 cases显示文摘 | Thibault de La Motte Rouge Patricia Pautier Annie Rey Pierre Duvillard Pierre Kerbrat Frédéric Troalen Philippe Morice Christine Haie-Meder Stéphane Culine Catherine Lhommé | 2010 | European Journal of Cancer2010，，2： | 1 |
| 9 | Enteral glutamine infusion modulates ubiquitination of heat shock proteins, Grp-75 and Apg-2, in the human duodenal mucosa显示文摘 | Julien Bertrand Alexis Goichon Philippe Chan Saida Azhar Stéphane Lecleire Nathalie Donnadieu David Vaudry Anne-Fran?oise Cailleux Pierre Déchelotte Mo?se Co?ffier | 2014 | Amino Acids2014，，4： | 1 |
| 10 | Risk factors of anxiety and depression in inflammatory bowel disease显示文摘 | Stéphane Nahon Pierre Lahmek Christelle Durance Alain Olympie Bruno Lesgourgues Jean‐Frédéric Colombel Jean‐Pierre Gendre | 2012 | Inflamm Bowel Dis2012，，11： | 1 |
| 11 | Numerical modelling of interfacial soil erosion with viscous incompressible flows显示文摘 | Frédéric Golay Damien Lachouette Stéphane Bonelli Pierre Seppecher | 2010 | Computer Methods in Applied Mechanics and Engineering2010，，： | 1 |
| 12 | Interfacial erosion: A three-dimensional numerical model显示文摘 | Frédéric Golay Damien Lachouette Stéphane Bonelli Pierre Seppecher | 2010 | Comptes rendus - Mécanique2010，，6： | 1 |
| 13 | Superoxide activates mitochondrial uncoupling proteins 显示文摘 | Echtay K S Roussel D St Pierre J | 2002 | Nature2002，415，1： | 1 |
| 14 | Effect of aminoglycoside use on residual renal function in peritoneal dialysis patients显示文摘 | Shemin D Maaz D St Pierre D | | 0，，1： | 1 |
| 15 | Structure-borne noise reduction in a truck cab interior using numerical techniques显示文摘 | Mohanty Amiya R St Barry D Pierre | 2000 | Applied Acoustics2000，59，： | 1 |
| 16 | Tuning of the crystallite and particle sizes of ZnO nanocrystalline materials in solvothermal synthesis and their photoeatalytic activity for dye degradation显示文摘 | John Becker Krishna Reddy Raghupathi Jordan St Pierre et d | 2011 | J Phys Chem C2011，115，13： | 1 |
| 17 | Superoxide activates mitochondrial uncoupling proteins 显示文摘 | Echtay KS Roussel D St Pierre J | 2002 | Nature2002，415，1： | 1 |
| 18 | Results of an Independent Evaluation of Project ALERT Delivered in Schools by Cooperative Extension显示文摘 | St Pierre T L Osgood D Mincemoyer C C | 2005 | Prevention Science2005，6，： | 1 |
| 19 | Effect of aminoglycoside use on residual renal function in peritoneal dialysis patients显示文摘 | Shemin D Maaz D St Pierre D | 1999 | Am J Kidney Dis1999，34，1： | 1 |
| 20 | Structure-borne noise reduction in a truck cab interior using numerical techniques 显示文摘 | Mohanty A R St Pierre B D Suruli-Narayanasami P | 2000 | Applied Acoustics2000，59，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员