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| 1 | Green tea extract:A potential cause of acute liver failure显示文摘The use of herbal products has increased significantly in recent years.Because these products are not subject to regulation by the Food and Drug Administration and are often used without supervision by a healthcare provider,the indication for and consumption of these supplements is quite variable.Moreover,their use is generally regarded as safe and natural by the lay-public.Unfortunately,there has been an increase in the number of reported adverse events occurring with the use of herbal products.We present a case of acute impending liver failure in an adolescent male using a weightloss product containing green tea extract.Our case adds to the growing concern surrounding the ingestion of green tea extract and serves to heighten healthcare provider awareness of a potential green tea extract hepatotoxicity.Despite the generally touted benefits of green tea as a whole,clinical concern regarding its use is emerging and has been linked to its concentration in multiple herbal supplements.Interestingly,the suspected harmful compounds are those previously proposed to be advantageous for weight-loss,cancer remedy,and anti-inflammatory purposes.Yet,we emphasize the need to be aware of not just green tea extract,but the importance of monitoring patient use of all dietary supplements and herbal products. | Shreena S Patel Stacey Beer Debra L Kearney Garrett Phillips Beth A Carter | 2013 | World Journal of Gastroenterology2013，19，31： | 3 |
| 2 | Statistical issues and approaches in endophenotype research显示文摘The endophenotype concept was initially proposed to enhance the power of genetic studies of complex disorders. It is closely related to the genetic component in a liability-threshold model; a perfect endophenotype should have a correlation of 1 with the genetic component of the liability to disease. In reality, a putative endophenotype is unlikely to be a perfect representation of the genetic component of disease liability. The magnitude of the correlation between a putative endophenotype and the genetic component of disease liability can be estimated by fitting multivariate genetic models to twin data. A number of statistical methods have been developed for incorporating endophenotypes in genetic linkage and association analyses with the aim of improving statistical power. The most recent of such methods can handle multiple endophenotypes simultaneously for the greatest increase in power. In addition to increasing statistical power, endophenotype research plays an important role in helping to understand the mechanisms which connect the associated genetic variants with disease occurrence. Novel statistical approaches may be required for the analysis of the complex relationships between endophenotypes at different levels and how they converge to cause the occurrence of disease. | SHAM Pak Chung CHERNY Stacey S HALL Mei-Hua | 2011 | Chinese Science Bulletin2011，56，32： | 2 |
| 3 | Creation of residual flows in a partially stratified estuary 显示文摘 | Stacey M C Burau J R Monismith S G | 2001 | Journal of Geophysical Research2001，106，17： | 1 |
| 4 | Isolation and properties of oligosaccharides obtained by controlled fragmentation of chitin显示文摘 | Barker S A Foster A B Stacey M | 1958 | J Chem Soc1958，，： | 1 |
| 5 | Distinct, crucial roles of flavonoids during legume nodulation显示文摘 | Subramanian S Stacey G Yu O | 2007 | Trends Plant Sci2007，12，： | 1 |
| 6 | Cloning and functional characterization of a constitutively express-ed nitrate transporter gene,Osnrtl,from rice显示文摘 | LIN C M KOH S STACEY G | 2000 | Plant Physiology2000，122，2： | 1 |
| 7 | Statin use reduces decline in lung function:VA Normative Aging Study显示文摘 | Stacey EA Augusto AL David S | 2007 | Am J Respir Crit Care Med2007，176，8： | 1 |
| 8 | Variable Number of Tandem Repeat Polymorphisms (VNTRs) in the ACAN C, ene Associated with Pectus Excavatum显示文摘 | Stacey M Neumann S Doolvy A | 2010 | Clin Genet2010，78，： | 1 |
| 9 | The role of CD8~ Th2 Lymphocytes in the development of smoking-related lung damage 显示文摘 | Mottolis S Kleimberg J Stacey M A | 1997 | Biochem Biophys Res Commun1997，239，： | 1 |
| 10 | Endogenous steroid hormone Concentrations and risk of breast cancer among premenopausal women显示文摘 | STACEY A SHELLEY S | 2006 | Journal of the National Cancer Institute2006，98，19： | 1 |
| 11 | Biological variation for N-terminal pro-and B-type natriuretic peptides and implications for therapertic monitoring of patients with congestive heart failure显示文摘 | AlanHB Andrew S Stacey W | 2003 | Am J Cardiol2003，92，5： | 1 |
| 12 | Distinct, crucial roles offlavonoids during legume nodulation显示文摘 | Subramanian S Stacey G Yu O | 2007 | Trends in Plant Science2007，12，7： | 1 |
| 13 | Controlled synthesis of high quality Micro/Nano-diamonds by microwave plasma chemical vapor deposition 显示文摘 | Stacey A Aharonovich I Prawer S | 2009 | Diam Relat Mater2009，18，： | 1 |
| 14 | Two newly identified genetic determinants of pigmentation in Europeans显示文摘 | Sulem P Gudbjartsson D F Stacey S N | 2008 | Nature Genetics2008，40，7： | 1 |
| 15 | Resuscitation in pregnancy 显示文摘 | Morris S Stacey M | 2003 | Br Med J2003，327，： | 1 |
| 16 | Effects of endogenous sali- cylic acid on nodulation in the model legumes lotus japonicus and Medicago truncatula 显示文摘 | Stacey G McAlvin C B Kim S Y | 2006 | Plant Physiology2006，141，4： | 1 |
| 17 | The application of lead isotopes to the problems of ore genesis and ore prospect evaluation:A review显示文摘 | DOE B R STACEY J S | 1974 | Economic Geology1974，67，6： | 1 |
| 18 | Eotaxin expression andeosinophilic inflammation in asthma显示文摘 | Mattoli S Stacey MA Sun G | 1997 | Biochem Biophys Res Commun1997，，2： | 1 |
| 19 | The condensation of long-chain fatty acids with polysaccharides and proteins 显示文摘 | Jones A S Kaye M A G Stacey M | 1952 | J Chem Soc1952，，： | 1 |
| 20 | The application of lead isotopes to problem of ore genesis and prospect evaluation:a review显示文摘 | Doe B R Stacey J S | 1974 | Economic Geology1974，69，： | 1 |
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