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| 1 | 循证医学论争的哲学分析(上)显示文摘首先 ,我们认为EBM的支持者对EBM的定义过于宽泛 ,甚至是空洞的 ,这正是当前的有关讨论不明朗的原因 ;对此我们提出了一种更明晰的解释 ,重新阐述EBM的含义及与其他医学方法的关系。第二 ,EBM的支持者通常依据ThomasKuhn的哲学著作来说明EBM是一种Kuhn式的“范式转化” ;我们认为 ,这种说明是一种严重的错误 ,并且使有关EBM的争论过度的偏离常轨。第三 ,我们建议以W .V .Quine的信仰之网的哲学观念来理解EBM及其与其他医学方法的关系 ,这是一种更富有成果的理解方式。基于这种理解 。 | Scott R Sehon Donald E Stanley 韩鹏 程伟 | 2004 | 医学与哲学2004,25,2: | 9 |
| 2 | Randomized trial in malignant biliary obstruction:Plastic vs partially covered metal stents显示文摘AIM:To compare efficacy and complications of par-tially covered self-expandable metal stent(pcSEMS)to plastic stent(PS)in patients treated for malignant,infrahilar biliary obstruction.METHODS:Multicenter prospective randomized clinical trial with treatment allocation to a pcWallstent(SEMS)or a 10 French PS.Palliative patients aged≥18,for infrahilar malignant biliary obstruction and a Karnofsky performance scale index>60%from 6 participating North American university centers.Primary endpoint was time to stent failure,with secondary outcomes of death,adverse events,Karnofsky performance score and short-form-36 scale administered on a three-monthly basis for up to 2 years.Survival analyses were performed for stent failure and death,with Cox proportional hazards regression models to determine significant predictive characteristics.RESULTS:Eighty-five patients were accrued over 37mo,42 were randomized to the SEMS group and 83patients were available for analyses.Time to stent failure was 385.3±52.5 d in the SEMS and 153.3±19.8 d in the PS group,P=0.006.Time to death did not differ between groups(192.3±23.4 d for SEMS vs211.5±28.0 d for PS,P=0.70).The only significant predictor was treatment allocation,relating to the time to stent failure(P=0.01).Amongst other measured outcomes,only cholangitis differed,being more common in the PS group(4.9%vs 24.5%,P=0.029).The small number of patients in follow-up limits longitudinal assessments of performance and quality of life.From an initially planned 120 patients,only 85 patients were recruited.CONCLUSION:Partially covered SEMS result in a longer duration till stent failure without increased complication rates,yet without accompanying measurable benefits in survival,performance,or quality of life. | Peter L Moses Khalid M AlNaamani Alan N Barkun Stuart R Gordon Roger D Mitty M Stanley Branch Thomas E Kowalski Myriam Martel Viviane Adam | 2013 | World Journal of Gastroenterology2013,19,46: | 6 |
| 3 | 循证医学论争的哲学分析(下)显示文摘 | Scott R Sehon Donald E Stanley 韩鹏 程伟 | 2004 | 医学与哲学2004,25,3: | 5 |
| 4 | Peroxisomes,oxidative stress,and inflammation显示文摘Peroxisomes are intracellular organelles mediating a wide variety of biosynthetic and biodegradative reactions.Included among these are the metabolism of hydrogen peroxide and other reactive species,molecules whose levels help define the oxidative state of cells.Loss of oxidative equilibrium in cells of tissues and organs potentiates inflammatory responses which can ultimately trigger human disease.The goal of this article is to review evidence for connections between peroxisome function,oxidative stress,and inflammation in the context of human health and degenerative disease.Dysregulated points in this nexus are identified and potential remedial approaches are presented. | Stanley R Terlecky Laura J Terlecky Courtney R Giordano | 2012 | World Journal of Biological Chemistry2012,3,5: | 4 |
| 5 | Patients undergoing infrainguinal bypass to treat atherosclerotic vascular disease are underprescribed cardioprotective medications: effect on graft patency, limb salvage, and mortality显示文摘 | Peter K Henke Susan Blackburn Mary C Proctor Jeri Stevens Debabrata Mukherjee Sanjay Rajagopalin Gilbert R Upchurch James C Stanley Kim A Eagle | 2004 | Journal of Vascular Surgery2004,,: | 2 |
| 6 | Chemical vapor deposition of Si nanowires nucleated by TiSi2 islands on Si显示文摘 | Kamins T I Stanley Williams R Chang Y L | 2000 | Appl Phys Lett2000,76,5: | 2 |
| 7 | Purification and characterization of secretory IgA from baboon eolostrum显示文摘 | Shearer M H Corbitt S D Stanley J R | 1997 | Journal of Immunological Methods1997,204,1: | 1 |
| 8 | Scaling behavior in the dynamics of an economic index显示文摘 | Mantegna R N Stanley H E | 1995 | Nature1995,376,6: | 1 |
| 9 | Scaling behaviour in the growth of companies显示文摘 | Stanley M H R Amaral L A N Buldyrev S V Havlin S Leschhorn H Maass P Salinger M A Stanley H E | 1996 | Nature1996,379,: | 1 |
| 10 | Carbon-13 NMR studies of flavonoids-Ⅲ:Naturally occurring flavonoid glycosides and their acylated derivatives显示文摘 | Markham K R Ternai B Stanley R | 1978 | Tetrahedron1978,34,9: | 1 |
| 11 | Scaling behavior in the dynamics of an economic index显示文摘 | Mantegna R N Stanley H E | 1995 | Nature1995,376,6: | 1 |
| 12 | Effect of cigarette smoking on nasal mucociliary clearance and ciliary beat frequency显示文摘 | STANLEY P WILSON R GREENSTONE M | 1986 | Thorax1986,41,7: | 1 |
| 13 | Scaling behavior in the dynamics of an economics index显示文摘 | Mantegna R N Stanley H E | 1995 | Nature1995,376,: | 1 |
| 14 | CO2 and CH4 emissions from streams in a lake-rich landscape: patterns, controls, and regional significance 显示文摘 | CRAWFORD J T LOTTIG N R STANLEY E H | 2014 | Global Biogeochemical Cycles2014,,20: | 1 |
| 15 | Competitive coevolufion through evolutionary com-plexificafion显示文摘 | Stanley K O Miikkulainen R | 2004 | Journal of Artificial Intelli- gence Research2004,,21: | 1 |
| 16 | Effects of the Mi 1, N and tabasco genes on infection and reproduction of Meloidogyne mayaguensis on tomato and pepper genotypes 显示文摘 | Brito J A Stanley J D Kaur R | 2007 | Journal of Nematology2007,39,4: | 1 |
| 17 | 显示文摘 | Adams J J Weiland T L Stanley J R | 2005 | Proc of SPIE2005,5647,: | 1 |
| 18 | Nitric oxide reversibly inhibits the migration of cultured vascular smooth muscle cells显示文摘 | Sarkar R Meinberg EG Stanley JC | 1996 | Circ Res1996,78,: | 1 |
| 19 | Scaling behavior in the dynamics of an economic index显示文摘 | Mantegna R N Stanley H E | 1995 | Nature1995,376,: | 1 |
| 20 | Sand Filtration Studied with Radiotracers 显示文摘 | Stanley D R | 1955 | JSED ASCE1955,81,1: | 1 |