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| 1 | The role of cholesterol ih the biosynthesis of beta-amyloid 显示文摘 | Frears ER Stephens DJ Waiters CE | 1999 | Neuroreport1999，10，8： | 1 |
| 2 | Complete, minimal and model-continuous kinematic models for robot calibration显示文摘 | Klaus Schr?er Stephen L Albright Michael Grethlein | 1997 | Robotics and Computer Integrated Manufacturing1997，，1： | 1 |
| 3 | Genotyping of peach and nectarine cultivars with SSR and SRAP molecular markers显示文摘 | RIAZ A POTI?ER D STEPHEN M | 2004 | Journal of America Horticultural Science2004，129，2： | 1 |
| 4 | Adapting Strategic Niche Management for evaluating radical transport policies the case of the Durham Road Ac- cess Charging Scheme Original显示文摘 | PETROS IEROMONACHOU STEPHEN POTI'ER MARCUS ENOCH | 2004 | Research Article Interna- tional Journal of Transport Management2004，，2： | 1 |
| 5 | Plaque rupture in humans and mice 显示文摘 | Stephen MS Zorina SG Michael ER | 2007 | Arterioscler Thromb Vasc Biol2007，27，4： | 1 |
| 6 | The role of cholesterol in the biosynthesis of beta-amyloid显示文摘 | Frears ER Stephens DJ Waiters CE | 1999 | Neuroreport1999，10，8： | 1 |
| 7 | The role of cholesterol in the biosynthesis of beta-amyloid显示文摘 | Frears ER Stephens DJ Walters CE | 1999 | Neuroreport1999，10，8： | 1 |
| 8 | Clinical Review: Treatment of Vitreoretinal Lymphoma显示文摘 | Jacob Pe’er Fred. H. Hochberg C. Stephen Foster | 2009 | Ocular Immunology & Inflammation2009，，5： | 1 |
| 9 | The role of cholesterol in the biosynthesis of beta-amyloid 显示文摘 | Frears ER Stephens DJ Waiters CE | 1999 | Neuroreport1999，10，： | 1 |
| 10 | The role of cholesterol in the biosynthesis of betaanyloid显示文摘 | Frears ER Stephens DJ Walters CE | 1999 | Neuroreprot1999，10，8： | 1 |
| 11 | Causality assessment methods in drug induced liver injury: Strengths and weaknesses显示文摘 | Miren García-Cortés Camilla Stephens M. Isabel Lucena Alejandra Fernández-Casta?er Raúl J. Andrade | 2011 | Journal of Hepatology2011，，3： | 1 |
| 12 | 大型患者队列人群中肺高血压前期和死亡率、住院率的关系显示文摘肺高血压与所有心肺疾病死亡率增加相关。肺高血压定义为平均肺动脉压(mean pulmonary artery pressure,mPAP)≥25mm Hg(1mm Hg=0.133kPa),而mPAP〈25mm Hg与临床预后的相关性尚未知。方法:研究人员回顾性分析美国退伍军人事务部医疗系统中行右心导管插入术(right heart catheterization,RHC)(2007-2012年)的退伍军人资料(n=21 727;随访时间中位数为908d)。 | 刘莉 叶鹏 Maron BA Hess E Maddox TM Opotowsky AR Tedford RJ Lahm T Joynt KE Kass DJ Stephens T Stanislawski MA Swenson ER Goldstein RH Leopold JA Zamanian RT Elwing JM Plomondon ME Grunwald GK Barón AE Rumsfeld J Choudhary G | 2016 | 中华高血压杂志2016，24，2： | 1 |
| 13 | Pancreatic anastomotic failure after pancreaticoduodenectomy显示文摘 | Stephen RG David ER Clayton AG | 2000 | Am Surg2000，180，1： | 1 |
| 14 | The role of cholesterol in the bioxynthesis of beta-amyloid 显示文摘 | Frears ER Stephens DJ Walters CE Davies H | 1999 | Neuroreport1999，10，8： | 1 |
| 15 | Radiographic examination of the small bowel:suevey of practice patterns in the United States显示文摘 | Alice SH Marc SL Stephen ER | 2004 | Radiology2004，231，2： | 1 |
| 16 | Discovery of small-molecule hu- man immunodeficiency virus type 1 entry inhibi- tors that target the gp120-binding domain of CD4 显示文摘 | QUANEN Y STEPHEN A G ADELSBERG- ER J W | 2005 | J Virol2005，79，： | 1 |
| 17 | Idiopathic eosinophilic esophagitisi in adult::the ringed esophagus显示文摘 | Stefan LZ Marc SL Stephen ER | 2005 | Radiology2005，236，1： | 1 |
| 18 | Loss of connectivity in Alzheimer's disease:an evaluation of white matter tract integrity with colored coded tensor MR diffusion tensor imaging显示文摘 | Stephen ER Chen F Jonathan BC | 2000 | J Neurol Neurosurg Psychiatry2000，69，4： | 1 |
| 19 | A variant in IL6ST with a selective IL-11 signaling defect in human and mouse显示文摘The GP130 cytokine receptor subunit encoded by IL6ST is the shared receptor for ten cytokines of the IL-6 family. We describe a homozygous non-synonymous variant in IL6 ST(p.R281 Q) in a patient with craniosynostosis and retained deciduous teeth. We characterize the impact of the variant on cytokine signaling in vitro using transfected cell lines as well as primary patient-derived cells and support these findings using a mouse model with the corresponding genome-edited variant Il6 st p.R279 Q. We show that human GP130 p.R281 Q is associated with selective loss of IL-11 signaling without affecting IL-6, IL-27, OSM, LIF, CT1, CLC, and CNTF signaling. In mice Il6 st p.R279 Q lowers litter size and causes facial synostosis and teeth abnormalities. The effect on IL-11 signaling caused by the GP130 variant shows incomplete penetrance but phenocopies aspects of IL11 RA deficiency in humans and mice. Our data show that a genetic variant in a pleiotropic cytokine receptor can have remarkably selective defects. | Tobias Schwerd Freia Krause Stephen R.F.Twigg Dominik Aschenbrenner Yin-Huai Chen Uwe Borgmeyer Miryam Müller Santiago Manrique Neele Schumacher Steven A.Wall Jonathan Jung Timo Damm Claus-Christian Glüer Jürgen Scheller Stefan Rose-John E.Yvonne Jones Arian Laurence Andrew O.M.Wilkie Dirk Schmidt-Arras Holm H.Uhlig | 2020 | Bone Research2020，8，2： | 0 |
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