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| 1 | Update on hepatocellular carcinoma: Pathologists' review显示文摘Histopathologic diversity and several distinct histologic subtypes of hepatocellular carcinoma(HCC) are well-recognized. Recent advances in molecular pathology and growing knowledge about the biology associated with distinct histologic features and immuno-profile in HCC allowed pathologists to update classifications. Improving sub-classification will allow for more clinically relevant diagnoses and may allow for stratification into biologically meaningful subgroups. Therefore, immuno-histochemical and molecular testing are not only diagnostically useful, but also are being incorporated as crucial components in predicting prognosis of the patients with HCC. Possibilities of targeted therapy are being explored in HCC, and it will be important for pathologists to provide any data that may be valuable from a theranostic perspective. Herein, we review and provide updates regarding the pathologic sub-classification of HCC.Pathologic diagnostic approach and the role of biomarkers as prognosticators are reviewed. Further, the histopathology of four particular subtypes of HCC:Steatohepatitic, clear cell, fibrolamellar and scirrhous-and their clinical relevance, and the recent consensus on combined HCC-cholangiocarcinoma is summarized. Finally, emerging novel biomarkers and new approaches to HCC stratification are reviewed. | Tony El Jabbour Stephen M Lagana Hwajeong Lee | 2019 | World Journal of Gastroenterology2019，25，14： | 25 |
| 2 | Chemotherapy plus radiotherapy compared with radiotherapy alone in the treatment of locally advanced,unresectable,non-small cell lung cancer:a Meta-analysis显示文摘 | Robert S Pritchard EL Stephen P | 2009 | Annal Int Med2009，，： | 1 |
| 3 | Chemotherapy plus Radiotherapy Alone in the Treatment of Locally Advanced, Unresectable, Non-Small-Cell Lung Cancer: a Meta-Analysis显示文摘 | Robert S Pritchard EL Stephen P | 2005 | Annal Int Med2005，129，3： | 1 |
| 4 | ICSH recommendations for the measurement of haemoglobin A2显示文摘 | STEPHENS AD ANGASTINIOTIS M BAYSAL E el al | 2012 | Int J Lab Hematol2012，34，1： | 1 |
| 5 | Supply Chain Collaboration: Making Sense of the Strategy Continuum 显示文摘 | Matthias Holweg Stephen Disney Jan Holmstom el al | 2005 | European Management Journal2005，23，2： | 1 |
| 6 | Tranexamic Acid Reduces Perioperative Blood Loss in Adult Patients Having Spinal Fusion Surgery显示文摘 | Jean Wong Hossam El Beheiry Yoga Raja Rampersaud Stephen Lewis Henry Ahn Yoshani De Silva Amir Abrishami Naseer Baig Robert J. McBroom Frances Chung | 2008 | Anesthesia & Analgesia2008，，5： | 1 |
| 7 | Technical reports: modification of alkaline microgel electrophoresis for sensitive detection of DNA damage显示文摘 | Singh NP Stephens RE Schneider EL | 1994 | Int J Radiat Biol1994，66，： | 1 |
| 8 | A serpin gene cluster on human chromosome 6p25 contains PI6, PI9 and ELANH2 which have a common structure almost identical to the 18 q21 ovalbuman serpin genes 显示文摘 | Sun J Stephens R Mirza G el al | 1998 | Cytogenet Cell Gen- et1998，82，34： | 1 |
| 9 | Human CD44 CD2^+4 thymocytes and peripheral T cells have immune sup- pressive activity in vitro显示文摘 | Stephens LA Mottet C Mason D el al | 2001 | Eur J Immunol2001，31，4： | 1 |
| 10 | Brain abscess: Association with pulmonary arteriovenous fistula and hereditary hemorrhagic telangiectasia; Report of three cases 显示文摘 | Gelfand MS Stephens DS Howell EL | 1988 | Am J Med1988，85，： | 1 |
| 11 | Reemergence of apoptotic cells between fractionated doses in irradiated murine tumors显示文摘 | Meyn RE Stephens LC Hunter NR at el | 1994 | Int J Radiat Oncol Biol Phys1994，30，3： | 1 |
| 12 | Endogenous signals released from necrotic cells augment inflammatory responses to bacterial endotoxin显示文摘 | Rabab El Mezayen Mohamed El Gazzar Michael C. Seeds Charles E. McCall Stephen C. Dreskin Mark R. Nicolls | 2007 | Immunology Letters2007，，1： | 1 |
| 13 | Single day, patient-initiated famciclovir therapy for recurrent genital herpes: A randomized, double-blind, placebo-controlled trial 显示文摘 | Fred Y Aoki Stephen Francisco D M el al | 2006 | Clin Infect Dis2006，42，： | 1 |
| 14 | Guidelines for the provision and assessmenl of nulrilion support therapy in the critically m patient显示文摘 | STEPHEN A MCCLAVE M D ROBERT C el aI | 2009 | JPEN2009，33，3： | 1 |
| 15 | A small-cell lung cancer genome with complex signatures of tobacco exposure 显示文摘 | Pleasance El? Stephens PJ O'Meara S | 2010 | Na- ture2010，463，7278： | 1 |
| 16 | A randomized, comparative pilot study of azithromycin versus benza- thine penicillin G for treatment of early syphilis 显示文摘 | Hook EW Martin DH Stephens J et el | 2002 | Sex Transm Dis2002，29，： | 1 |
| 17 | Chemotherapy plus radiotherapy alone in the treatment of locally advanced,unresectable,non-small cell lung cancer:a Meta-analysis显示文摘 | Robert S Pritchard EL Stephen P | 2005 | Annal Int Med2005，129，3： | 1 |
| 18 | In situ and in vitro im- pacts of the Deepwater Horizon oilspill on Vibrio parahaemolyticus 显示文摘 | Stephens EL Molina V Cole KM | 2013 | Marine Pollution Bulletin2013，75，12： | 1 |
| 19 | Fracture abundance and pat-terns in the Subandean fold and thrust belt, Devonian Huamampampa Formation petroleum reservoirs and outcrops, Argentina and Bolivia 显示文摘 | Juan FI Stephen EL John NH | 2012 | Marine and Petroleum Geology2012，35，1： | 1 |
| 20 | The effect of cigarette smoke on adherence of respiratory pathogens to buccal epithelial cells显示文摘 | OMAR R AHMER El STEPHEN D | 1999 | FEMS Immunol and Med Microbiol1999，23，3： | 1 |
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