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| 1 | Appendectomy and Clostridium difficile colitis:Relationships revealed by clinical observations and immunology显示文摘Advances in understanding the interaction between the human immune system and the microbiome have led to an improved understanding of the function of the vermiform appendix as a safe-house for beneficial bacteria in the colon.These advances have been made despite long standing clinical observations that the appendectomy is a safe and effective procedure.However,more recent clinical data show that an appendectomy puts patients at increased risk for recurrent Clostridium difficile(C.difficile)-associated colitis,and probably other diseases associated with an altered microbiome.At the same time,appendectomy does not apparently put patients at risk for an initial onset of C.difficile-associated colitis.These clinical observations point toward the idea that the vermiform appendix might not effectively protect the microbiome in the face of broad spectrum antibiotics,the use of which precedes the initial onset of C.difficile-associated colitis.Further,these observations point to the idea that historically important threats to the microbiome such as infectious gastrointestinal pathogens have been supplanted by other threats,particularly the use of broad spectrum antibiotics. | Nathan L Sanders R Randal Bollinger Ryan Lee Steven Thomas William Parker | 2013 | World Journal of Gastroenterology2013，19，34： | 2 |
| 2 | The potential of brain natriunetic peptide as a biomarker for New York Heart Association class during the outpatient treatment of heart failure 显示文摘 | Lee S C Stevens T L Sandberg S M | 2002 | J Card Fail2002，8，3： | 1 |
| 3 | Time course of detection of viral and serologic markers preceding human immunodeficiency virus type 1 seroconversion显示文摘 | Steven N Francis Lee Marcia L | 2000 | J Infect Dis2000，175，： | 1 |
| 4 | The potential of brain natriuretic peptide as a biomarker for New York Heart Association class during the out patient treatment of heart failure显示文摘 | Lee SC Stevens T L Sandberg S M | 2002 | J Card Fail2002，8，3： | 1 |
| 5 | Smoking and schizophrenia:abnormal nicotinic receptor expression显示文摘 | Leonard S Bresse C Adams C Benhammou K Gault J Steven K Lee M Adler L Olincy A Ross R Freedman R | 2000 | Eur J Pharmacol2000，393，： | 1 |
| 6 | The potential of brain natriuretic peptide as a biomarker for New York Heart Association class during the outpatient treatment of heart failure 显示文摘 | LeeS C Stevens T L Sandberg S M | 2002 | J CardiolFail2002，8，3： | 1 |
| 7 | The potential of brain natriaretic pepfide as a biomarker for New York Heart Association class during the out patient treatment of heart failure显示文摘 | Lee S C Stevens T L Sandberg S M | 2002 | J Card Fail2002，8，3： | 1 |
| 8 | Continuous atmospheric plasma fluorination of carbon fibres显示文摘 | Kingsley K C Ho Adam F Lee Steven L | 2008 | Composites:Part A2008，39，： | 1 |
| 9 | A Multidisciplinary Approach to the Development of a Cervical Spine Clearance Protocol: Process, Rationale, and Initial Results 显示文摘 | Steven L Lee Matthew Sena | 2003 | Elsevier Science2003，10，38： | 1 |
| 10 | The potential of brain natriuretic peptide as a biomarker for New York Heart As- sociation class during the outpatient treatment of heart failure 显示文摘 | LEE S C STEVENS T L SANDBERG S M | 2002 | J Card Fail2002，8，3： | 1 |
| 11 | The potential of brain natriuretic peptide as a biomarker for New York Heart Association class during the out patient treatment of heart failure 显示文摘 | Lee S C Stevens T L Sandberg S M | 2002 | J Card Fail2002，8，3： | 1 |
| 12 | Platelet-Mediated Modulation of Adaptive Immunity显示文摘 | Bennett D Elzey Jun Tian Robert J Jensen Axel K Swanson Jason R Lees Steven R Lentz Colleen S Stein Bernhard Nieswandt Yiqiang Wang Beverly L Davidson Timothy L Ratliff | 2003 | Immunity2003，，1： | 1 |
| 13 | The potential of brain natriuretic peptide as a biomarker for New York Heart Association class during the outpatient treatment of heart failure 显示文摘 | LEE S C STEVENS T L SANDBERG S M | 2002 | J Card Fail2002，8，3： | 1 |
| 14 | Prediction of the location and size of the stomach using patient characteristics for retrospective radiation dose estimation following radiotherapy显示文摘 | Stephanie Lamart Rebecca Imran Steven L Simon Kazutaka Doi Lindsay M Morton Rochelle E Curtis Choonik Lee Vladimir Drozdovitch Roberto Maass-Moreno Clara C Chen Millie Whatley Donald L Miller Karel Pacak Choonsik Lee | 2013 | Physics in Medicine and Biology2013，，24： | 1 |
| 15 | The Potential of brain natriuretic peptide as a biomarker for New York Heart Association class during the outpatient of heart failure 显示文摘 | Lee S C Stevens T L Sandberg S M | 2002 | J Card Fail2002，8，3： | 1 |
| 16 | The potential of brain natriuretic peptide as a biomarker for New York Heart Association class during the outpatient treatment of heart failure显示文摘 | LEE S C STEVENS T L SANGDBERG S M | 2002 | J Card Fail2002，8，3： | 1 |
| 17 | Low temperature iron- and nickel-catalyzed reactions leading to coalbed gas formation显示文摘 | Juan Carlos Medina Steven J Butala Calvin H Bartholomew Milton L Lee | 2000 | Geochimica et Cosmochimica Acta2000，，4： | 1 |
| 18 | A Mmultidisciplinary Aapproach to the Ddevelopment of a Ccervical Sspine Cclearance Pprotocol:Pprocess,Rrationale,and linitial Rresults显示文摘 | Steven L Lee SL Matthew Sena M Greenholz SK | 2003 | Pediatr Surg Elsevier Science2003，10，38： | 1 |
| 19 | The potential of brain natriuretic peptide as a biomarker for New York Heart Association class during the outpatient treatment of heartfailure显示文摘 | STEVENS T L SANDBERG S M | 2002 | J Card Fail2002，8，3： | 1 |
| 20 | Asymptomatic cardiac disease following mediastinal irradiation显示文摘 | Paul A Heidenreich Steven L Hancock Byron K Lee Carol S Mariscal Ingela Schnittger | 2003 | Journal of the American College of Cardiology2003，，4： | 1 |
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