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| 1 | 美国国家卒中协会短暂性脑缺血发作处理指南显示文摘目的:短暂性脑缺血发作(TIA)是常见和重要的卒中先兆。其处理方法多样,大多数发表的指南在近年来均未被更新。我们试图制定一个全面的、无偏倚的、循证的TIA处理指南。方法:根据一种客观标准(可以预测在该研究领域中执业医师对专家提名的文献测量学方法)挑选出15名专家组成员。通过系统回顾检索到过去发表的指南,由专家对其中的推荐意见的质量进行独立评价。选择出质量最高的推荐意见,然后让专家组采用改良Delphi法通过多次问卷调查的方式进行修订,从而对新的修改达成共识。给专家们提供近期临床研究的系统评价,要求专家根据新的证据判断措辞修改的合理性并且根据证据等级和质量对最终的推荐意见进行评定。不允许专家在预期有可能存在任何利益冲突的专题方面提出推荐意见。结果:通过系统回顾检索到257个指南,其中有13篇文献包括的137条推荐意见符合所有纳入标准。需要6次重复的问卷调查对53条最终推荐意见的措辞达成共识。最终的推荐意见涉及TIA的初步处理、评价、内科治疗、外科治疗和危险因素控制。结论:对TIA患者医疗诊治的最终推荐意见强调了紧急评价和治疗的重要性。这种用于制定本指南的新方法是可行的,考虑到了快速更新并能减少偏倚。 | S. Claiborne Johnston Mai N. Nguyen-Huynh Miriam E. Schwarz Kate Fuller Christina Williams S. Andrew Josephsort Graeme J. Hankey Robert G. Hart Steven R. Levine Jose Biller Robert D. Brown Ralph L. Sacco L. Jaap Kappelle Peter J. Koudstaal Julien Bogousslavsky Louis R. Caplan Jan van Gijn Ale Algra Peter M. Rothwell Harold P. Adams Gregory W. Albers 李海峰(译) | 2007 | 国际脑血管病杂志2007，15，3： | 5 |
| 2 | Notch mediates TGFα-induced changes in epithelial differentiation during pancreatic tumorigenesis显示文摘 | Yoshiharu Miyamoto Anirban Maitra Bidyut Ghosh Ulrich Zechner Pedram Argani Christine A. Iacobuzio-Donahue Virote Sriuranpong Tatsuya Iso Ingrid M. Meszoely Michael S. Wolfe Ralph H. Hruban Douglas W. Ball Roland M. Schmid Steven D. Leach | 2003 | Cancer Cell2003，，6： | 3 |
| 3 | Differentiating intraductal papillary mucinous neoplasms from other pancreatic cystic lesions显示文摘Intraductal papillary mucinous neoplasms(IPMN) can be difficult to distinguish from other cystic lesions of the pancreas.To understand better and discuss the current knowledge on this topic,the literature and the institutional experience at a large pancreatic disease center have been reviewed.A combination of preoperative demographic,historical,radiographic,laboratory data,as well as postoperative pathologic analyses can often distinguish IPMN from other lesions in the differential diagnosis. | Steven C Cunningham Ralph H Hruban Richard D Schulick | 2010 | World Journal of Gastrointestinal Surgery2010，2，10： | 3 |
| 4 | Cholangiocarcinoma: A Spectrum of Intrahepatic, Perihilar, and Distal Tumors显示文摘 | Attila Nakeeb Henry A. Pitt Taylor A. Sohn JoAnn Coleman Ross A. Abrams Steven Piantadosi Ralph H. Hruban Keith D. Lillemoe Charles J. Yeo John L. Cameron | 1996 | Annals of Surgery1996，，4： | 3 |
| 5 | Laparoscopic Cholecystectomy in the Cirrhotic Patient: Predictors of Outcome显示文摘 | Ralph C. Quillin Justin M. Burns Jaime A. Pineda Dennis Hanseman Steven M. Rudich Michael J. Edwards Amit D. Tevar | 2012 | Surgery2012，，： | 2 |
| 6 | A Lethally Irradiated Allogeneic Granulocyte-Macrophage Colony Stimulating Factor-Secreting Tumor Vaccine for Pancreatic Adenocarcinoma: A Phase II Trial of Safety, Efficacy, and Immune Activation显示文摘 | Lutz Eric Charles J. Yeo Keith D. Lillemoe Barbara Biedrzycki Barry Kobrin Joseph Herman Elizabeth Sugar Steven Piantadosi John L. Cameron Sara Solt Beth Onners Irena Tartakovsky Miri Choi Rajni Sharma Peter B. Illei Hruban Ralph H. Ross A. Abrams Dung Le | 2011 | Annals of Surgery2011，，2： | 2 |
| 7 | Functional Defects in the Fanconi Anemia Pathway in Pancreatic Cancer Cells显示文摘 | Michiel S. Van der Heijden Jonathan R. Brody Eike Gallmeier Steven C. Cunningham David A. Dezentje Dong Shen Ralph H. Hruban Scott E. Kern | 2004 | The American Journal of Pathology2004，，2： | 2 |
| 8 | Pancreatic cancer显示文摘 | Theresa Pluth Yeo Ralph H Hruban Steven D Leach Robb E Wilentz Taylor A Sohn Scott E Kern Christine A Iacobuzio-Donahue Anirban Maitra Michael Goggins Marcia I Canto Ross A Abrams Daniel Laheru Elizabeth M Jaffee Manuel Hidalgo Charles J Yeo | 2002 | Current Problems in Cancer2002，，4： | 2 |
| 9 | Efficacy of oral palonose- tron compared to intravenous palonosetron for the prevention of chemotherapy-induced nausea and vomiting associated with mod- erately emetogenic chemotherapy : a phase 3 trial 显示文摘 | Ralph B Steven G Edwin FG | 2013 | Support Care Cancer2013，21，5： | 1 |
| 10 | Paclitaxel Stent Coating Inhibits Neointimal Hyperplasia at 4 Weeks in a Porcine Model of Coronary Restenosis显示文摘 | Alan W. Heldman Linda Cheng G. Mark Jenkins Phillip F. Heller Dong-Woon Kim Melvin Ware Cynthia Nater Ralph H. Hruban Banafsheh Rezai Benjamin S. Abella Katherine E. Bunge James L. Kinsella Steven J. Sollott Edward G. Lakatta Jeffrey A. Brinker William L. | 2001 | Circulation: Journal of the American Heart Association2001，，： | 1 |
| 11 | Promoter(4G/5G) Plasmon-ogen Activator Inhibitorol Genotype and Plasmonogen Activator Inhibitor-1 Levels in Blacks,Hispanics,and Non-Hispanics Whites显示文摘 | Festa MD Ralph JR Steven S | 2003 | Circulation2003，107，： | 1 |
| 12 | CYP82E4-mediated nicotine to nornicotine conversion in tobacco is regulated by a senescence-specific signaling pathway显示文摘 | Manohar Chakrabarti Steven W. Bowen Nicholas P. Coleman Karen M. Meekins Ralph E. Dewey Balazs Siminszky | 2008 | Plant Molecular Biology2008，，4： | 1 |
| 13 | DEATH IN THE OPERATING ROOM: AN ANALYSIS OF A MULTI-CENTER EXPERIENCE显示文摘 | David B. Hoyt Eileen M. Bulger M. Margaret Knudson John Morris Ralph lerardi Harvey J. Sugerman Steven R. Shackford Jeffery Landercasper Robert J. Winchell Gregory Jurkovich Susan C. Coffey Michael Chang Keith F. O?Malley James Lowry Gino T. Trevisani Tho | 1994 | The Journal of Trauma: Injury Infection and Critical Care1994，，3： | 1 |
| 14 | Pancreaticoduodenectomy for Cancer of the Head of the Pancreas 201 Patients显示文摘 | Charles J. Yeo John L. Cameron Keith D. Lillemoe James V. Sitzmann Ralph H. Hruban Steven N. Goodman William C. Dooley JoAnn Coleman Henry A. Pitt | 1995 | Annals of Surgery1995，，： | 1 |
| 15 | Predicting resectability of periampullary cancer with three-dimensional computed tomography显示文摘 | Michael G. House M.D. Charles J. Yeo M.D. John L. Cameron M.D. Kurt A. Campbell M.D. Richard D. Schulick M.D. Steven D. Leach M.D. Ralph H. Hruban M.D. Karen M. Horton M.D. Elliot K Fishman M.D. Keith D. Lillemoe M.D | 2004 | Journal of Gastrointestinal Surgery2004，，3： | 1 |
| 16 | Promoter(4G/5G)Plasmonogen Activator Inhibitor-1 Genotype and Plasmonogen Activator Inhibitor-1 Levels in Blacks,Hispanics,and Non- Hispanics Whites显示文摘 | Festa MD Ralph JR Steven S | 2003 | Circulation2003，107，： | 1 |
| 17 | Magnetic resonance imaging identifies multifocal and multicentric disease in breast cancer patients who are eligible for partial breast irradiation显示文摘 | Hania A.Al‐Hallaq Loren K.Mell Julie A.Bradley Lucy F.Chen Arif N.Ali Ralph R.Weichselbaum Gillian M.Newstead Steven J.Chmura | 2008 | Cancer2008，，9： | 1 |
| 18 | Primary Prevention of Ischemic Stroke: A Statement for Healthcare Professionals From the Stroke Council of the American Heart Association显示文摘 | Larry B. Goldstein Robert Adams Kyra Becker Curt D. Furberg Philip B. Gorelick George Hademenos Martha Hill George Howard Virginia J. Howard Bradley Jacobs Steven R. Levine Lori Mosca Ralph L. Sacco David G. Sherman Philip A. Wolf Gregory J. del Zoppo | 2001 | Stroke: Journal of the American Heart Association2001，，1： | 1 |
| 19 | Efficacy and Safety of Fasudil in Patients With Stable Angina显示文摘 | Ralph M. Vicari Bernard Chaitman Deborah Keefe William B. Smith Steven G. Chrysant Melvin J. Tonkon Neville Bittar Robert J. Weiss Hugo Morales-Ballejo Udho Thadani | 2005 | Journal of the American College of Cardiology2005，，10： | 1 |
| 20 | Robust simple sequence repeat markers for spruce (Picea spp.) from expressed sequence tags显示文摘 | Dainis Rungis Yanik Bérubé Jun Zhang Steven Ralph Carol E. Ritland Brian E. Ellis Carl Douglas J?rg Bohlmann Kermit Ritland | 2004 | Theoretical and Applied Genetics2004，，6： | 1 |
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