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12篇 您的检索式:作者名="Stewart FR"
    题名 作者 年代 出处 被引量
1Human apoE isoforms differentially regulate brain amyloid-显示文摘Castellano JM Kim J Stewart FR 2011Sci Transl Med2011,3,:1
2Root replacement for all allografts in young recipients显示文摘O'Brien MF Stewart FR Stafford EC 1993J Thorac Cardiovasc Surg1993,105,3:1
3Human apo E isoforms differentially regulate brainamyloid-beta peptide clearance显示文摘Castellano JM Kim J Stewart FR 2011Sci Transl Med2011,3,:1
4In vivo microdialysis revea decrease of brain interstitia s age-dependent fluid tau levels in P301S human tau transgenic mice显示文摘Yamada K Cirrito JR Stewart FR 2011J Neurosci2011,31,13:1
5Phenanthrene-4,5-quinones: a synthesis of morphenol 显示文摘Hewgill FR Stewart JM 1988J Chem Soc Perkin Trans1988,46,6:1
6Ultrastructural studies in APP/PS1 mice expressing human ApoE isoforms: implications for Alzheimer's disease 显示文摘Dikranian K Kim J Stewart FR 2012Int J Clin Exp Pathol2012,5,:1
7Human apo E isoforms differentially regulate brain amyloid-βpeptide clearance显示文摘Castellano JM Kim J Stewart FR 2011Sci Transl Med2011,3,89:1
8Human apoE isoforms differentially regulate brain amyloid-β peptide clearance显示文摘Castellano JM Kim J Stewart FR 2011Sci Transl Med2011,3,89:1
9Human apoE isoforms differentially regulate brain amyloid-13 peptide clearance 显示文摘Castellano JM Kim J Stewart FR 2011Sci Transl Med2011,3,89:1
10In vivo mierodialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tan transgenic mice 显示文摘Yamada K Cirrito JR Stewart FR 2011Neurosci2011,31,13:1
11Human apoE isoforms differentially regulate brain amyloid-beta peptide clearance 显示文摘Castellano JM Kim J Stewart FR 2011Sci Transl Med2011,3,89:1
12Global Transcriptional Profile of Tranosema rostrale Ichnovirus Genes in Infected Lepidopteran Hosts and Wasp Ovaries显示文摘The ichnovirus TrIV, transmitted by the endoparasitic wasp Tranosema rostrale to its lepidopteran host during oviposition, replicates asymptomatically in wasp ovaries and causes physiological dysfunctions in parasitized caterpillars. The need to identify ichnoviral genes responsible for disturbances induced in lepidopteran hosts has provided the impetus for the sequencing and annotation of ichnovirus genomes, including that of TrIV. In the latter, 86 putative genes were identified, including 35 that could be assigned to recognized ichnoviral gene families. With the aim of assessing the relative importance of each TrIV gene, as inferred from its level of expression, and evaluating the accuracy of the gene predictions made during genome annotation, the present study builds on an earlier qPCR quantification of transcript abundance of TrIV rep ORFs, in both lepidopteran and wasp hosts, extending it to other gene families as well as to a sample of unassigned ORFs. We show that the majority (91%) of putative ORFs assigned to known gene families are expressed in infected larvae, while this proportion is lower (67%) for a sample taken among the remaining ORFs. Selected members of the TrV and rep gene families are shown to be transcribed in infected larvae at much higher levels than genes from any other TrIV gene family, pointing to their likely involvement in host subjugation. In wasp ovaries, the transcriptional profile is dominated by a rep gene and a member of a newly described gene family encoding secreted proteins displaying a novel cysteine motif, which we identified among previously unassigned ORFs.Asieh Rasoolizadeh Frédéric Dallaire Don Stewart Catherine Béliveau Renée Lapointe Michel Cusson 2009Virologica Sinica2009,24,5:0
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