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| 1 | Early-onset colorectal cancer:A sporadic or inherited disease?显示文摘Colorectal cancer is the third most common cancer diagnosed worldwide.Although epidemiology data show a marked variability around the world,its overall incidence rate shows a slow but steady decrease,mainly in developed countries.Conversely,early-onset colorectal cancer appears to display an opposite trend with an overall prevalence in United States and European Union ranging from 3.0% and 8.6%.Colorectal cancer has a substantial proportion of familial cases.In particular,early age at onset is especially suggestive of hereditary predisposition.The clinicopathological and molecular features of colorectal cancer cases show a marked heterogeneity not only between early- and late-onset cases but also within the early-onset group.Two distinct subtypes of early-onset colorectal cancers can be identified:a 'sporadic' subtype,usually without family history,and an inherited subtype arising in the context of well defined hereditary syndromes.The pathogenesis of the early-onset disease is substantially well characterized in the inherited subtype,which is mainly associated to the Lynch syndrome and occasionally to other rare mendelian diseases,whereas in the 'sporadic' subtype the origin of the disease may be attributed to the presence of various common/rare genetic variants,so far largely unidentified,displaying variable penetrance.These variants are thought to act cumulatively to increase the risk of colorectal cancer,and presumably to also anticipate its onset.Efforts are ongoing in the attempt to unravel the intricate genetic basis of this 'sporadic' early-onset disease.A better knowledge of molecular entities and pathways may impact on family-tailored prevention and clinical management strategies. | Vittoria Stigliano Lupe Sanchez-Mete Aline Martayan Marcello Anti | 2014 | World Journal of Gastroenterology2014，20，35： | 10 |
| 2 | 化疗栓塞联合其他方法治疗肝细胞癌的评价显示文摘 引言
肝癌是世界上第5 种最常见的肿瘤且其发病率仍在上升.在欧洲,80%的肝细胞癌(HCC)并发于肝硬化且是其主要死因.
虽然公布了一些方案,但对HCC 病人的常规治疗策略并没有取得世界范围内的统一.巴塞罗那临床肝癌(BCLC)分类和治疗方案于最近公布.按照该方案,放疗[包括切除、肝移植、经皮消融(经皮乙醇注射以及射频)]可以运用于30%~40%的HCC 病人,而另外更多的病人则需要采用其他的手段.…… | Marelli L Stigliano R Triantos C 刘军麟 | 2007 | 中华普通外科学文献(电子版)2007，1，3： | 3 |
| 3 | Transarterial Therapy for Hepatocellular Carcinoma: Which Technique Is More Effective? A Systematic Review of Cohort and Randomized Studies显示文摘 | Laura Marelli Rosa Stigliano Christos Triantos Marco Senzolo Evangelos Cholongitas Neil Davies Jonathan Tibballs Tim Meyer David W. Patch Andrew K. Burroughs | 2007 | CardioVascular and Interventional Radiology2007，，1： | 2 |
| 4 | Transartefial ther- apy for hepatocellular carcinoma: Which technique is more effective? A systematic review of cohort and random- ized studies显示文摘 | Marelli L Stigliano R Tfiantos C | 2007 | Cardiovasc Intervent Radiol2007，30，1： | 1 |
| 5 | Is DD3 a new prostate-specific gene显示文摘 | GANDINI O LUCI L STIGLIANO A | 2003 | Anticancer res2003，23，1： | 1 |
| 6 | Tomato Rablla characterization evidenced a difference between SYP121-dependent and SYP122-dependent exocytosis显示文摘 | Rehman R U Stigliano E Lycett G W | 2008 | Plant and cell physiology2008，49，5： | 1 |
| 7 | Transarterial therapy for hepatocellular carcinoma:which technique is more effec- tive? A systematic review of cohort and randomized studies 显示文摘 | Marelli L Stigliano R Triantos C | 2007 | Cardiovasc Intervent Radiol2007，30，： | 1 |
| 8 | Assessment of the Genetic Effects of Polymorphisms in the Osteoprotegerin Gene, TNFRSF11B, on Serum Osteoprotegerin Levels and Carotid Plaque Vulnerability显示文摘 | Giuseppe Straface Federico Biscetti Dario Pitocco Giovanni Bertoletti Maria Misuraca Claudio Vincenzoni Francesco Snider Vincenzo Arena Egidio Stigliano Flavia Angelini Luigi Iuliano Stefania Boccia Chiara de Waure Francesco Giacchi Giovanni Ghirlanda And | 2011 | Stroke2011，，： | 1 |
| 9 | Treatment outcomes for hepatocellular carcinoma using chemoembolization in combination with other therapies 显示文摘 | Marelli L Stigliano R Triantos C | 2006 | Cancer Trea Rev2006，32，8： | 1 |
| 10 | Should we biopsy each liver mass su- spicious for HCC before liver transplantation?-no, please don't显示文摘 | Stigliano R Burroughs AK | 2005 | J Hepatol2005，43，4： | 1 |
| 11 | Is DD3 a new prostate- specific gene显示文摘 | Gandini O LueiL Stigliano A | 2003 | Anticancer Res2003，，： | 1 |
| 12 | Liver transplantation and hepatitis C virus: systematic review of antiviral therapy显示文摘 | Triantos C Samonakis D Stigliano R | 2005 | Transplantation2005，79，3： | 1 |
| 13 | Transarterial therapy for hepatocellular carcinoma: which technique is more effective? A systematic review of cohort and randomized studies 显示文摘 | Marelli L Stigliano R Triantos C | 2007 | Cardiovase Intervent Radiol2007，30，： | 1 |
| 14 | Transarterial therapy for hepatoeellular carcinoma: which technique is more effective? A systematic review of cohort and randomized studies显示文摘 | Marelli L Stigliano R Triantos C | 2007 | Cardiovase Intervent Radiol2007，30，1： | 1 |
| 15 | Transarterial therapy for hepatocellular carcinoma:which technique is more effective?A systematic review of cohort and randomized studies显示文摘 | Marelli L Stigliano R Triantos C | 2007 | Cardiovasc Inter vent Radiol2007，30，： | 1 |
| 16 | Prospective multi-center ran- domized trim comparing banding ligation with sclemtherapy of esopha- geal varice 显示文摘 | Masci E Stigliano R Mariani A | 1999 | Hepatogastroentemlogy1999，46，27： | 1 |
| 17 | Transarterial therapy for hepatocellular car- cinoma: Which technique is more effective? A systematic review of cohort and random- ized studies 显示文摘 | Marelli L Stigliano R Triantos C | 2007 | Cardiovascular and inter- ventional radiology2007，30，1： | 1 |
| 18 | Glypican-3 reexpression regulates apoptosis in murine adenocarcinoma mammary cells modulating PI3K/Akt and p38MAPK signaling pathways显示文摘 | C. Buchanan I. Stigliano H. M. Garay-Malpartida L. Rodrigues Gomes L. Puricelli M. C. Sogayar E. Bal de Kier Joffé M. G. Peters | 2010 | Breast Cancer Research and Treatment2010，，3： | 1 |
| 19 | Topical butyrate for acute radiation proctitis: randomised, crossover trial显示文摘 | P Vernia PL Fracasso V Casale G Villotti A Marcheggiano V Stigliano P Pinnaro V Bagnardi R Caprilli | 2000 | The Lancet . 2000 (9237)2000，，9237： | 1 |
| 20 | Glypican-3 regulates migration, adhesion and actin cytoskeleton organization in mammary tumor cells through Wnt signaling modulation显示文摘 | Ivan Stigliano Lydia Puricelli Jorge Filmus Mari Cleide Sogayar Elisa Bal de Kier Joffé María Giselle Peters | 2009 | Breast Cancer Research and Treatment2009，，2： | 1 |
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