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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | NEW TOXOPLASMA GONDII GENOTYPES ISOLATED FROM FREE-RANGE CHICKENS FROM THE FERNANDO DE NORONHA, BRAZIL: UNEXPECTED FINDINGS显示文摘 | Dubey J P Rajendran C Costa D G C Ferreira L R Kwok O C H Qu D Su C Marvulo M F V Alves L C Mota R A Silva J C R | 2010 | The Journal of Parasitology2010，，4： | 2 |
| 3 | Variable scaling hybrid differential evolution for solving network reconfiguration of distribution systems显示文摘 | Chiou J P Chang C F Su C T | 2005 | IEEE Trans on Power Systems2005，20，2： | 1 |
| 4 | A novel drought-inducible gene,A TAF1,encodes a NAC family protein that negatively regulates the expression of stress-responsive genes in Arabidopsis显示文摘 | LU P L CH EN N Z AN R SU Z QI B S REN F CHEN J WANG X C | 2007 | Plant Molecular Biology2007，63，2： | 1 |
| 5 | Exploratory learning and exploitative learning in different organizational structures 显示文摘 | Su Z F Li J Y Yang Z P | 2011 | Asia Pacific Journal of Management2011，28，4： | 1 |
| 6 | The regulatory roles of microRNA-146 b-5 p and its target platelet-derived growth factor receptor alpha (PDGFRA) in erythropoiesis and megakaryocytopoiesis 显示文摘 | ZHAI P F WANG F SU R | 2014 | J Biol Chem2014，289，22： | 1 |
| 7 | The TIL commissioning and performance显示文摘 | X Zhang W Zheng X Wei F Jing Z Sui K Zheng Q Xu X Yuan X Jiang L Yang P Ma M Li J Wang D Hu S He F Li Z Peng B Feng H Zhou L Guo X Li X Zhang J Su Q Zhu H Yu R Zhao C Ma H He D Fan W Zhang | 2008 | Journal of Physics: Conference Series2008，，3： | 1 |
| 8 | Attapulgite-Fe304 magnetic nanoparticles via co-precipitation technique显示文摘 | LIU Y LIU P SU Z LI F WEN F | 2008 | Applied Surface Science2008，255，5： | 1 |
| 9 | Double emulsion templated microcapsules with single hollow cavities and thickness-con- trollable shells 显示文摘 | Gao F Su Z G Wang P | 2009 | Langmuir2009，25，6： | 1 |
| 10 | Target-cluster Fusion Approach for Classifying High Resolution IKONOS Imagery显示文摘 | SU Y HUANG P S LIN C F | 2004 | Vision Image and Signal Processing2004，151，4： | 1 |
| 11 | Purification of single walled carbon nanotubes synthesized by the catalytic decomposition of hydrocarbons显示文摘 | F LI H M CHENG Y T XING P H TAN G SU | 2000 | Carbon2000，38，： | 1 |
| 12 | Retroperitoneal mixed germ cell tumor mimicking a renal neoplasm: a case report显示文摘 | Su T F Yu C P Wu S T | 2012 | Urology2012，80，3： | 1 |
| 13 | Quantification of seven pheny- lpropanoid compounds in Chinese Cinnamomi Cortex and Ramu- lus by HPLC显示文摘 | Yuan P F Ma Y J Su D | 2015 | Chin Pharm Sci2015，24，9： | 1 |
| 14 | Ant direction hybrid differential evolution for solving large capacitor placement problems显示文摘 | Chiou J P Chang C F Su C T | 2004 | IEEE Transactions on Power Systems2004，19，4： | 1 |
| 15 | Design of steel triangular plate energy absorbers for seismic-resistant construction 显示文摘 | Tsai K C Hong C P Su Y F | 1993 | Earthquake Spectra1993，9，3： | 1 |
| 16 | Green-light-emitting ZnSe nanowires fabricated via vapor phase growth显示文摘 | Xiang B Zhang H Z Li G H Yang F H Su F H Wang R M Xu J Lu G W Sun X C Zhao Q Yu D P | 2003 | Appl Phys Lett2003，82，19： | 1 |
| 17 | Rice is more efficient in arsenite uptake and translocation than wheat and barley显示文摘 | Su Y H McGrath S P Zhao F J | 2010 | Plant and Soil2010，328，12： | 1 |
| 18 | Observation of nighttime nitrous acid (HONO) formation at a non-urban site during PRIDEPRD2004 in China显示文摘 | Su H Cheng Y F Cheng P | | 0，，25： | 1 |
| 19 | Finding an anti-risk path between two nodes in undirected graphs显示文摘 | Xiao P Xu Y F Su B | 2009 | Journal of Combinatorial Opti- mization2009，17，3： | 1 |
| 20 | Design of steel triangular plate energy absorbers for seismic resistant construction显示文摘 | TsaiKC ChenH W HongC P Su Y F | 1993 | Earthquake Spectra1993，19，3： | 1 |
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