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4篇 您的检索式:作者名="Sufen Wu"
    题名 作者 年代 出处 被引量
1Particulate matter trends and quantification of the spring sand-dust contribution in Hohhot,Inner Mongolia,from 2013 to 2017显示文摘2013年9月国务院颁布了《大气污染防治行动计划》.研究其实施前后呼和浩特市大气污染物浓度变化及及原因;同时,分析了春季沙尘天气对于呼和浩特市大气环境颗粒物浓度的定量影响.结果表明:呼和浩特市大气环境质量持续改善,但大气污染物浓度仍然较高.PM_(2.5)和PM10年均浓度分别超过国家二级标准22.9%和35.7%;2013-2017年春季PM_(2.5)和PM10浓度降幅较大,沙尘天气对呼和浩特市PM_(2.5),PM10,和TSP浓度的绝对贡献范围分别在0.6-5.2μg m^(-3),9.0-16.9μg m^(-3)和14.7-30.0μg m^(-3).Wenkang Gao Lingyun Zhu Zhanyun Ma Qingxian Gao Xuepu Yu Sufen Wu Yu Gu 2021Atmospheric and Oceanic Science Letters2021,14,2:1
2Erratum to:SC79 promotes efficient entry of GDNF liposomes into brain parenchyma to repair dopamine neurons through reversible regulation of tight junction proteins显示文摘Erratum to Nano Research 2023,16(2):2695-2705 https://doi.org/10.1007/s12274-022-4857-6 The article SC79 promotes efficient entry of GDNF liposomes into brain parenchyma to repair dopamine neurons through reversible regulation of tight junction proteins,written by Xiaomei Wu et al.,was erroneously originally published electronically on the publisher’s internet portal(currently SpringerLink)on 14 September 2022 with Fig.1(f)and a zeta potential value in Section 3.1.Xiaomei Wu Li Wang Kai Wang Jia Ke Sufen Li Tingting Meng Hong Yuan Qirui Zhang Fuqiang Hu 2023Nano Research2023,16,7:0
3Motivational Orientation and Brand Familiarity: Positive Emotions and Skepticism toward Online Advertising Using the English Language显示文摘Mei-Rong Alice Chen Sufen Chen Couchen Wu 2015Journal of Literature and Art Studies2015,5,4:0
4SC79 promotes efficient entry of GDNF liposomes into brain parenchyma to repair dopamine neurons through reversible regulation of tight junction proteins显示文摘Glial cell line-derived neurotrophic factor(GDNF),a disease-modifying drug for Parkinson’s disease(PD)is in Phase 2 clinical trials(EudraCT number:2011-003866-34),however it is administered by direct intrastriatal delivery via stereotaxy,which is accompanied with intracranial infection,brain tissue damage,and other complications.In addition,because of complex administration routes,clinical trials of GDNF have yielded contrary results,largely due to differences in dose and concentration brought by intracranial device.Herein,a small molecular agonist SC79 was screened to open blood-brain barrier(BBB)and promote GDNF liposomes to get into brain.SC79 reversibly reduces the expression of claudin-5,one of dominant tight junctions of BBB.Animal study showed SC79 promoted liposomes to enter into brain parenchyma 2.43 times more than that of the control.Motor deficits of PD mice receiving SC79 and brain-targeted GDNF liposomes were recovered by 36.70%and tyrosine hydroxylase positive neurons in striatum were restored by 39.90%.Our combination therapy effectively avoids the side effects such as secondary infection and uneven delivery caused by intracranial injection,improving patients’compliance and providing valuable research ideas for the clinic.Xiaomei Wu Li Wang Kai Wang Jia Ke Sufen Li Tingting Meng Hong Yuan Qirui Zhang Fuqiang Hu 2023Nano Research2023,16,2:0
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