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| 1 | Autoantibody against angiotensin AT1 receptor from preeclamptic patients enhances collagen-induced human platelet aggregation显示文摘Hypercoagulability,血小板激活,和 thrombocytopenia 是 preeclampsia 的主要特征,但是他们的负责的内在的分子的机制仍然保持阴暗。最近的研究证明了对血管收缩素 II 类型 1 受体(AT1-AA ) 的自身抗体为 preeclampsia 组成一个新奇风险因素。然而,在血小板激活的 AT1-AA 和在 preeclampsia 的 hypercoagulability 的角色从来没被调查过。在现在的学习,我们决定了 AT1-AA 是否在 vitro 支持血小板聚集,并且把潜在的位于 \O 下面机制。AT1-AA 被连接酶的 immunosorbent 试金检测。在从 preeclamptic 病人净化的免疫球蛋白 G 部分以后,积极 sera 被加到从健康志愿者,血小板聚集和细胞内部的 Ca2+ 孤立的血小板层次被检测。AT1-AA 显著地在 vitro 提高了导致骨胶原的血小板聚集,效果由 AT1 受体对手 losartan 堵住了。另外, AT1-AA 在整个实验增加了并且维持导致骨胶原的 cytosolic 钙集中。我们第一次证明 AT1-AA 显著地在 vitro 通过血管收缩素类型 1 受体激活支持导致骨胶原的血小板聚集,潜在地经由增加的细胞内部的 Ca2+ 集中,作为一个潜在的贡献者支持 AT1-AA 到 preeclampsia 的 hypercoagulable 状态。 | Kehua Bai Ke Wang Xiaoyu Li Jie Wang Jie Zhang LiSong Jin Wang Suli Zhang Wayne Bond Lau Xinliang Ma Huirong Liu | 2013 | Acta Biochimica et Biophysica Sinica2013,45,9: | 2 |
| 2 | Decentralized Resilient H_∞Load Frequency Control for Cyber-Physical Power Systems Under DoS Attacks显示文摘This paper designs a decentralized resilient H_(∞)load frequency control(LFC)scheme for multi-area cyber-physical power systems(CPPSs).Under the network-based control framework,the sampled measurements are transmitted through the communication networks,which may be attacked by energylimited denial-of-service(DoS)attacks with a characterization of the maximum count of continuous data losses(resilience index).Each area is controlled in a decentralized mode,and the impacts on one area from other areas via their interconnections are regarded as the additional load disturbance of this area.Then,the closed-loop LFC system of each area under DoS attacks is modeled as an aperiodic sampled-data control system with external disturbances.Under this modeling,a decentralized resilient H_(∞)scheme is presented to design the state-feedback controllers with guaranteed H∞performance and resilience index based on a novel transmission interval-dependent loop functional method.When given the controllers,the proposed scheme can obtain a less conservative H_(∞)performance and resilience index that the LFC system can tolerate.The effectiveness of the proposed LFC scheme is evaluated on a one-area CPPS and two three-area CPPSs under DoS attacks. | Xin Zhao Suli Zou Zhongjing Ma | 2021 | IEEE/CAA Journal of Automatica Sinica2021,8,11: | 1 |
| 3 | High Fe^(LS)(C)electrochemical activity of an iron hexacyanoferrate cathode boosts superior sodium ion storage显示文摘Sodium iron hexacyanoferrate(FeHCF)is one of the most promising cathode materials for sodium-ion batteries(SIBs)due to its low cost theoretical capacity.However,the low electrochemical activity of Fe^(LS)(C)in FeHCF drags down its practical capacity and potential plateau.Herein,FeHCF with high Fe^(LS)(C)electrochemical activity(C-FeHCF)is synthesized via a facile citric acid-assisted solvothermal method.As the cathode of SIBs,C-FeHCF shows superior cycling stability(ca.87.3%capacity retention for 1000 cycles at 10 C)and outstanding rate performance(ca.68.5%capacity retention at 50 C).Importantly,the contribution of Fe^(LS)(C)to the whole capacity was quantitatively analyzed via combining dQ/dV and discharge curve for the first time,and the index reaches 44.53%for C-FeHCF,close to the theoretical value.In-situ X-ray diffraction proves the structure stability of C-FeHCF during charge-discharge process,ensuring its superior cycling performance.Furthermore,the application feasibility of the C-FeHCF cathode in quasi-solid SIBs is also evaluated.The quasi-solid SIBs with the C-FeHCF cathode exhibit excellent electrochemical performance,delivering an initial discharge capacity of 106.5 mAh g^(−1) at 5 C and high capacity retention of 89.8%over 1200 cycles.This work opens new insights into the design and development of advanced cathode materials for SIBs and the beyond. | Junhong Guo Fan Feng Shiqiang Zhao Zhenhai Shi Rui Wang Meng Yang Fangfang Chen Suli Chen Zi-Feng Ma Tianxi Liu | 2023 | Carbon Energy2023,5,5: | 1 |
| 4 | Atomically dispersed dual Fe centers on nitrogen-doped bamboo-like carbon nanotubes for efficient oxygen reduction显示文摘Interfacial atomic configuration between dual-metal active species and nitrogen-carbon substrates is of great importance for improving the intrinsic activity of catalysts toward oxygen reduction reaction(ORR).Thus,from the atomic-scale engineering we develop a high intrinsic activity ORR catalyst in terms of incorporating atomically dispersed dual Fe centers(single Fe atoms and ultra-small Fe atomic clusters)into bamboo-like N-doped carbon nanotubes.Benefiting from atomically dispersed dual-Fe centers on the atomic interface of Fe-Nx/carbon nanotubes,the fabricated dual Fe centers catalyst exhibits an extremely high ORR activity(E_(onset)=1.006 V;E_(1/2)=0.90 V),beyond state-of-the-art Pt/C.Remarkably,this catalyst also shows a superior kinetic current density of 19.690 mA·cm^(−2),which is 7 times that of state-of-the-art Pt/C.Additionally,based on the excellent catalyst,the primary Zn-air battery reveals a high power density up to 137 mW·cm^(−2) and sufficient potential cycling stability(at least 25 h).Undoubtedly,given the unique structure–activity relationship of dual-Fe active species and metal-nitrogen-carbon substrates,the catalyst will show great prospects in highly efficient electrochemical energy conversion devices. | Ligang Ma Junlin Li Zhiwei Zhang Hao Yang Xueqin Mu Xiangyao Gu Huihui Jin Ding Chen Senlin Yan Suli Liu Shichun Mu | 2022 | Nano Research2022,15,3: | 0 |
| 5 | Versatile functions of RNA m6A machinery on chromatin显示文摘m6A,a conserved and abundant modification on RNA,regulates RNA processing and function.RNA m6A machinery,including writers,erasers,and readers of m6A,is indispensable for m6A installation and function.Intriguingly,recent studies have revealed that m6A machinery can be recruited to chromatin by pleiotropic factors,including nascent RNA,transcription factors,regulatory RNA,histone modifications,and epigenetic machinery.Consequently,recruitment of m6A machinery can directly regulate chromatin biology,such as transcription,DNA damage repair,and DNA recombination beyond installation of m6A on nascent mRNA.Here,we discuss recent evidence showing that m6A machinery is targeted to chromatin and the direct biological consequences along with the underlying mechanisms. | Tanjing Song Suli Lv Neng Li Xuefeng Zhao Xianyun Ma Yingying Yan Weixia Wang Lidong Sun | 2022 | Journal of Molecular Cell Biology2022,14,3: | 0 |
| 6 | A New Position Calibration Method for MUSER Images显示文摘The Mingantu Spectral Radioheliograph(MUSER),a new generation of solar dedicated radio imagingspectroscopic telescope,has realized high-time,high-angular,and high-frequency resolution imaging of the Sun over an ultra-broadband frequency range.Each pair of MUSER antennas measures the complex visibility in the aperture plane for each integration time and frequency channel.The corresponding radio image for each integration time and frequency channel is then obtained by inverse Fourier transformation of the visibility data.However,the phase of the complex visibility is severely corrupted by instrumental and propagation effects.Therefore,robust calibration procedures are vital in order to obtain high-fidelity radio images.While there are many calibration techniques available—e.g.,using redundant baselines,observing standard cosmic sources,or fitting the solar disk—to correct the visibility data for the above-mentioned phase errors,MUSER is configured with non-redundant baselines and the solar disk structure cannot always be exploited.Therefore it is desirable to develop alternative calibration methods in addition to these available techniques whenever appropriate for MUSER to obtain reliable radio images.In the case where a point-like calibration source contains an unknown position error,we have for the first time derived a mathematical model to describe the problem and proposed an optimization method to calibrate this unknown error by studying the offset of the positions of radio images over a certain period of the time interval.Simulation experiments and actual observational data analyses indicate that this method is valid and feasible.For MUSER’s practical data the calibrated position errors are within the spatial angular resolution of the instrument.This calibration method can also be used in other situations for radio aperture synthesis observations. | Zhichao Zhou Yihua Yan Linjie Chen Wei Wang Suli Ma | 2022 | Research in Astronomy and Astrophysics2022,22,10: | 0 |