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| 1 | Waist Circumference Distribution of Chinese School-age Children and Adolescents显示文摘Background Waist circumference(WC),a proxy measure of central body fat,is a better predictor than overall body fat for cardiovascular risk factors in both adults and children.WC cutoffs have been established in many countries,but the national WC reference has not been developed in China.Objective To study the distribution of WC in a representative group of Chinese children for establishing Chinese WC cutoff points.Methods Cross-sectional data obtained from 15 mainland provinces and Hong Kong were collected.There were 160 225 children and adolescents aged 7-18 years old in total.The subjects were divided into five regional groups namely costal city,other city,north rural,south rural,and Hong Kong,for analyzing the distribution of WC.Results A large variation in WC distribution was found among the five groups for both sexes.Coastal city group had the highest P85 WC values consistently from the early school ages to 18-year-old compared with other groups.In contrast,south rural group had P85 values consistently lagged behind not only the city groups but also the north rural group.Hong Kong group had a high P85 WC at early ages,but because of the smaller increments of WC during adolescence,the P85 curve was gradually exceeded by the north rural groups.Catch-up trend was found in the two rural groups since the peak of puberty.These disparities were caused by not only socioeconomic and urban-rural factors but also north-south differences.Because of the regional variation of WC,a 'gradient' prevalence of central obesity was prospected among these groups.Comparisons of WC distributions between the Chinese and the U.S.A or Netherlands demonstrated the necessary of setting up China's own WC cutoffs.Sex and age-specific percentiles were obtained and smoothed by using LMS method.Conclusion The data obtained from this study could be used to develop national WC cutoff points for Chinese children and adolescents. | CHENG-YE JI RITA YT SUNG GUAN-SHENG MA JUN MA ZHONG-HU HE TIAN-JIAO CHEN | 2010 | Biomedical and Environmental Sciences2010,23,1: | 22 |
| 2 | Stereotactic body radiation therapy for non-small cell lung cancer:A review显示文摘Stereotactic body radiation therapy(SBRT) is the treatment of choice for medically inoperable patients with early stage non-small cell lung cancer(NSCLC). A literature search primarily based on PubMed electronic databases was completed in July 2018. Inclusion and exclusion criteria were determined prior to the search, and only prospective clinical trials were included. Nineteen trials from 2005 to 2018 met the inclusion criteria, reporting the outcomes of 1434 patients with central and peripheral early stage NSCLC. Patient eligibility,prescription dose and delivery, and follow up duration varied widely. Threeyears overall survival ranged from 43% to 95% with loco-regional control of up to 98% at 3 years. Up to 33% of patients failed distantly after SBRT at 3 years. SBRT was generally well tolerated with 10%-30% grade 3-4 toxicities and a few treatment-related deaths. No differences in outcomes were observed between conventionally fractionated radiation therapy and SBRT, central and peripheral lung tumors, or inoperable and operable patients. SBRT remains a reasonable treatment option for medically inoperable and select operable patients with early stage NSCLC. SBRT has shown excellent local and regional control with toxicity rates equivalent to surgery. Decreasing fractionation schedules have been consistently shown to be both safe and effective. Distant failure is common, and chemotherapy may be considered for select patients. However, the survival benefit of additional interventions, such as chemotherapy, for early stage NSCLC treated with SBRT remains unclear. | Kavitha M Prezzano Sung Jun Ma Gregory M Hermann Charlotte I Rivers Jorge A Gomez-Suescun Anurag K Singh | 2019 | World Journal of Clinical Oncology2019,10,1: | 10 |
| 3 | Long-term outcomes of interventions for radiation-induced xerostomia:A review显示文摘Xerostomia, or dry mouth, is a significant problem affecting quality of life in patients treated with radiation therapy for head and neck cancer. Strategies for reduction of xerostomia burden vary widely, with options including: sialagogue medications, saliva substitutes, acupuncture, vitamins, hyperbaric oxygen,submandibular gland transfer, and acupuncture or associated treatments. In this review, we sought to evaluate long-term outcomes of patients treated with various interventions for radiation-induced xerostomia. A literature search was performed using the terms 'xerostomia' and 'radiation' or 'radiotherapy'; all prospective clinical trials were evaluated, and only studies that reported 1 year follow up were included. The search results yielded 2193 studies, 1977 of which were in English. Of those, 304 were clinical trials or clinical studies. After abstract review, 23 trials were included in the review evaluating the following treatment modalities: pilocarpine(three); cevimeline(one); amifostine(eleven);submandibular gland transfer(five); acupuncture like transcutaneous electrical nerve stimulation(ALTENS)(one); hyperbaric oxygen(one); and acupuncture(one). Pilocarpine, cevimeline, and amifostine have been shown in some studies to improve xerostomia outcomes, at the cost of toxicity. ALTENS has similar efficacy with fewer side effects. Submandibular gland transfer is effective but requires an elective surgery, and thus may not always be appropriate or practical.The use of intensity-modulated radiation therapy, in addition to dose deescalation in select patients, may result in fewer patients with late xerostomia,reducing the need for additional interventions. | Sung Jun Ma Charlotte I Rivers Lucas M Serra Anurag K Singh | 2019 | World Journal of Clinical Oncology2019,10,1: | 4 |
| 4 | Mitochondrial H2O2 generated from electron transport chain complex I stimulates muscle differentiation显示文摘Mitochondrial 反应的氧种类(mROS ) 被认为有害到房间。然而,他们的生理的角色一直不作为表明调停人是彻底地探索了。这里,我们调查了 mROS 是否从 mitochondrial 电子运输链(mETC ) 产生了复杂我刺激了肌肉区别。我们的结果证明 mROS 的数量被增加并且锰 superoxide dismutase (MnSOD ) 在肌肉区别期间经由 NF-B 激活被导致。指向线粒体的抗氧化剂(MitoQ 和 MitoTEMPOL ) 和指向线粒体的过氧化氢酶减少了没有影响 ATP 的数量的 mROS 数量和压制的肌肉区别。Mitochondrial 改变包括在线粒体的数字和尺寸的 mitochondrial 抄写因素 A 和增加的正式就职,并且功能的激活在肌肉区别期间被观察。特别地,增加了 mETC 建筑群的表示层次我子单元和建筑群的一项更高的活动我比另外的建筑群被观察。毒鱼藤素, mETC 建筑群的一个禁止者我,减少 mitochondrial NADH/NAD+ 比率和 mROS 层次在肌肉区别期间。mROS 铺平的我用小介入 RNA 和毒鱼藤素减少了的建筑群的抑制,压制的肌肉区别,和有伴随物的弄空的 ATP 层次在 glycolysis 增加。从这些结果,我们结束那复杂我导出 | Seonmin Lee Eunyoung Tak Jisun Lee MA Rashid Michael P Murphy Joohun Ha Sung Soo Kim | 2011 | Cell Research2011,21,5: | 4 |
| 5 | DICER-LIKE3 Activity in Physcomitrella patens DICER-LIKE4 Mutants Causes Severe Developmental Dysfunction and Sterility显示文摘交易的小介入 RNA (ta-siRNAs ) 是在 microRNA 依赖的劈开,进双 stranded RNA 的变换,和骰子依赖者分阶段执行处理以后,免除 TAS 先锋抄本的植物特定的 siRNAs。象 microRNAs (miRNAs ) 一样, ta-siRNAs 在广泛的补充的地点的目标 RNA 的直接地点特定的劈开。这里,我们证明像骰子 Physcomitrella 圣餐盘(PpDCL4 ) 的 4 蛋白质为 21 核苷酸(nt ) 的生物的续生说是必要的 ta-siRNAs。在 PpDCL4 异种,离开缩放 23 并且 24-nt ta-siRNAs 作为 PpDCL3 的结果积累了活动。PpDCL4 异种在整个 Physcomitrella 开发显示严重畸形,包括绝育,那充分在 PpDCL3/PpDCL4 双异种植物被颠倒。因此, PpDCL3 活动,不是 PpDCL4 功能本身的损失,是 PpDCL4 显型的原因。另外,我们描述几新 Physcomitrella 交易 siRNA loci,其三属于一个新家庭, TAS6。TAS6 loci 被切的 miR156 和 miR529 目标地点代表并且在到 PpTAS3 loci 的靠近的最近。 | M. Asif Arif Isam Fattash Zhaorong Ma Sung Hyun Cho Anna K. Beike Ralf Reski Michael J. Axtell Wolfgang Frank | 2012 | Molecular Plant2012,5,6: | 4 |
| 6 | Degradation of carbofuran in aqueous solution by ultrasound and Fenton processes:Effect of system parameters and kinetic study显示文摘 | Ma Ying-Shih Sung Chi-Fangaa Lin Jih-Gawb | 2010 | Journal of Hazardous Materials2010,178,13: | 1 |
| 7 | Effects of combining electrical stimulation with BDNF gene transfer on the regeneration of crushed rat sciatic nerve显示文摘 | Alrashdan MS Sung MA Kwon YK | | 0,,: | 1 |
| 8 | Analysis of PARK genes in a Korean cohort of early-onset Parkinson disease显示文摘 | Jung Mi Choi Myoung Soo Woo Hyeo-Il Ma Suk Yun Kang Young-Hee Sung Seok Woo Yong Sun Ju Chung Joong-Seok Kim Hae-won Shin Chul Hyoung Lyoo Phil Hyu Lee Jong Sam Baik Sang-Jin Kim Mee Young Park Young Ho Sohn Jin-Ho Kim Jae Woo Kim Myung Sik Lee Myoung Cho | 2008 | Neurogenetics2008,,4: | 1 |
| 9 | Crosslinking of biological tissues using genipin and/or carbodiimide显示文摘 | Sung HW Chang WH Ma CY | 2003 | Journal of Biomedical Materials Research Part A2003,64,: | 1 |
| 10 | Crosslinking of biological tissues using genipin and/or carbodiimide显示文摘 | Sung HW Chang WH Ma CY | 2003 | J Biomed Mater Res A2003,64,3: | 1 |
| 11 | Degradation of carbofuran in aqueous solution by ultrasound and Fenton processes:Effect of system parameters and kinetic study显示文摘 | Ma Ylng-Shih Sung Chi-Fanga Lin Jih-Gaw | 2010 | Journal of Hazardous Materials2010,178,: | 1 |
| 12 | Endoscopy for upper gastrointestinalbleeding ; how urgent is it ? 显示文摘 | Tsoi KK Ma TK Sung JJ | 2009 | Nat Rev Gastroenterol Hepatol2009,68,: | 1 |
| 13 | Causes of mortality in patients with peptic ulcer bleeding:a prospective cohort study of 10,428cases显示文摘 | Sung JJ Tsoi KK Ma TK | 2010 | Am J Gastroenterol2010,105,1: | 1 |
| 14 | A pivotal role for p53 :balancing aerobic respiration and glycolysis显示文摘 | Wenzhe Ma Ho Joong Sung Joon Y | 2007 | J Bioenerg Biomembr2007,39,: | 1 |
| 15 | A new automatic parameter setting method of a simplified PCNN for image segmentation显示文摘 | Chen Yuli Park Sung Kee Ma Yide | 2011 | IEEE Transactions on Neural Networks2011,22,6: | 1 |
| 16 | Asian perspectives in management of inflammatory bowel disease:findings from a recent survey显示文摘 | Sung JJ Kamm MA Marteau P | 2010 | J Gastroenterol Hepatol2010,25,1: | 1 |
| 17 | Impact of age on preoperative and postoperative unnary incontinence quality of life显示文摘 | Sung VW Glasgow MA Wohlrab KJ | 2007 | Am J Obstet Gynecol2007,197,6: | 1 |
| 18 | An Automatic On-line Signature Verification System Based on Three Modals显示文摘 | Ma Mingming Sardha Wijesoma W Eric Sung | 2000 | IEEE Transactions on Industrial Electronics2000,4,5: | 1 |
| 19 | KChlPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain 显示文摘 | Rhodes KJ Carroll KI Sung MA | 2004 | J Neurosci2004,24,36: | 1 |
| 20 | KChlPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain 显示文摘 | Rhodes K J Carroll KI Sung MA | 2004 | J Neurosci2004,24,: | 1 |