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568篇 您的检索式:作者名="Suo Z"
    题名 作者 年代 出处 被引量
1Differentiation renders susceptibility to excitotoxicity in HT22 neurons显示文摘HT22 is an immortalized mouse hippocampal neuronal cell line that does not express cholinergic and glutamate receptors like mature hippocampal neurons in vivo.This in part prevents its use as a model for mature hippocampal neurons in memory-related studies.We now report that HT22 cells were appropriately induced to differentiate and possess properties similar to those of mature hippocampal neurons in vivo,such as becoming more glutamate-receptive and excitatory.Results showed that sensitivity of HT22 cells to glutamate-induced toxicity changed dramatically when comparing undifferentiated with differentiated cells,with the half-effective concentration for differentiated cells reducing approximately two orders of magnitude.Moreover,glutamate-induced toxicity in differentiated cells,but not undifferentiated cells,was inhibited by the N-methyl-Daspartate receptor antagonists MK-801 and memantine.Evidently,differentiated HT22 cells expressed N-methyl-D-aspartate receptors,while undifferentiated cells did not.Our experimental findings indicated that differentiation is important for immortalized cell lines to render post-mitotic neuronal properties,and that differentiated HT22 neurons represent a better model of hippocampal neurons than undifferentiated cells.Minchao He Jun Liu haowu Cheng Yigang Xing William Z Suo 2013Neural Regeneration Research2013,8,14:3
2Long-term effect of fertilizer and manure application on soil-carbon sequestration and soil fertility under the wheat-wheat-maize cropping system in northwest China 显示文摘SU Y Z WANG F SUO D R 2006Nutrient Cycling in Agroeeosystems2006,75,:1
3Persistent protease-activated receptor 4 signaling mediates thrombin-induced microglial activation 显示文摘Suo Z Wu M Citron BA 2003JBiolChem2003,278,31:1
4Nonequilibrium thermodynamics of dielectric elastomers显示文摘ZHAOX H KOH S J A SUO Z G International Journal of Applied Mechanics0,3,:1
5Microstructure and mechanical properties of bulk Mg-Zn-Ca amorphous alloys and amorphous matrix composites显示文摘LI Q F WENG H R SUO Z Y REN Y L YUAN X G QIU K Q 2008Mater Sci Eng A2008,487,:1
6Cracking in ceramics actuators caused by electrostriction显示文摘YANG W SUO Z 1994J Mech Phys Solids1994,42,:1
7显示文摘Shaw T M Suo Z Huang M 1999Appl Phys Lett1999,75,:1
8GRK5 deficiency leads to early Alzheimer-like pathology and working memory impairment显示文摘Suo Z Cox AA Bartelli N 0,,12:1
9Arsenic oxide targets stem cell marker CD133/p~minin-1 in gallbladder carcinoma 显示文摘Ai Z Pan H Suo T 2011Cancer Lett2011,310,2:1
10Method to analyze electromechanical stability of dielectric elastomers显示文摘ZHAO X H SUO Z G Applied Physics Letters0,1,06:1
11Alzheimer's beta-amyloid peptides induce inflammatory cascade in human vascular cells:the roles of cytokines and CD40显示文摘Suo Z Tan J Placzek A 1998Brain Res1998,807,12:1
12Mixed mode cracking in layered materials显示文摘Hutchinson J W Suo Z G 1992Advances in Applied Mechanics1992,29,:1
13Prognostic value of EphA2 and EphrinA1 squamous cell cervical carcinoma 显示文摘Wu D Suo Z Kristensen GB 2004Gynecol Oncol2004,92,4:1
14Delamination of stiff islands patterned on stretchable substrates 显示文摘LU N S YOON J SUO Z G 2007International Jour- nal of Materials Research2007,98,8:1
15Abnormality of G-protein- coupled receptor kinases at prodromal and early stages of Alzheimer's disease an association with early beta--amyloid accumulation 显示文摘Suo Z Wu M Citron B A 2004J Neurosci2004,24,:1
16FAP-a and uPA Show Different Expression Patterns in Premalignant and Malignant Esophageal Lesions 显示文摘Goscinski MA Suo Z Florenes VA 2008Uhrastruct Pathol2008,32,3:1
17Real-time PCR quantification of c-erbB-2 gene is an alternative for FISH in the clinical management of breast carcinoma patients 显示文摘Suo Z Daehli KU Lindboe CF 2004Int J Surg Pathol2004,12,4:1
18Capture efficiency of Escherichia coli in fimbriaemediated immunoimmobilization显示文摘Suo Z Yang X Deliorman M 2012Langmuir2012,28,2:1
19Deformation mechanisms in nacre显示文摘Wang R Z Suo Z Evans A G 0,,09:1
20Ductility of thin metal films on polymer sub- strates modulated by interracial adhesion 显示文摘LI T SUO Z 2007International Journal of Solids and Structures2007,44,6:1
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