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27篇 您的检索式:作者名="Surbek"
    题名 作者 年代 出处 被引量
1Stem cell treatment and cerebral palsy: Systemic review and meta-analysis显示文摘BACKGROUND Perinatal complications may result in life-long morbidities,among which cerebral palsy(CP)is the most severe motor disability.Once developed,CP is a nonprogressive disease with a prevalence of 1-2 per 1000 live births in developed countries.It demands an extensive and multidisciplinary care.Therefore,it is a challenge for our health system and a burden for patients and their families.Recently,stem cell therapy emerged as a promising treatment option and raised hope in patients and their families.AIM The aim is to evaluate the efficacy and safety of stem cell treatment in children with CP using a systematic review and meta-analysis METHODS We performed a systematic literature search on PubMed and EMBASE to find randomized controlled clinical trials(RCT)investigating the effect of stem cell transplantation in children with CP.After the review,we performed a randomeffects meta-analysis focusing on the change in gross motor function,which was quantified using the gross motor function measure.We calculated the pooled standardized mean differences of the 6-and/or 12-mo-outcome by the method of Cohen.We quantified the heterogeneity using the I-squared measure.RESULTS We identified a total of 8 RCT for a qualitative review.From the initially selected trials,5 met the criteria and were included in the meta-analysis.Patients’population ranged from 0.5 up to 35 years(n=282).We detected a significant improvement in the gross motor function with a pooled standard mean difference of 0.95(95%confidence interval:0.13-1.76)favoring the stem cell group and a high heterogeneity(I2=90.1%).Serious adverse events were rare and equally distributed among both intervention and control groups.CONCLUSION Stem cell therapy for CP compared with symptomatic standard care only,shows a significant positive effect on the gross motor function,although the magnitude of the improvement is limited.Short-term safety is present and further highquality RCTs are needed.Simone Eggenberger Céline Boucard Andreina Schoeberlein Raphael Guzman Andreas Limacher Daniel Surbek Martin Mueller 2019World Journal of Stem Cells2019,11,10:8
2Management der postpartalen Blutung (PPH)显示文摘D. Schlembach M.G. M?rtl T. Girard W. Arzt E. Beinder C. Brezinka K. Chalubinski D. Fries W. Gogarten B.-J. Hackel?er H. Helmer W. Henrich I. H?sli P. Husslein F. Kainer U. Lang G. Pfanner W. Rath E. Schleussner H. Steiner D. Surbek R. Zimmermann 2014Der Anaesthesist2014,,3:2
3Diagnosis and treatment of iron-deficiency anaemia during pregnancy and postpartum显示文摘Christian Breymann Christoph Honegger Wolfgang Holzgreve Daniel Surbek 2010Archives of Gynecology and Obstetrics2010,,5:1
4Diagnosis and treatment of peripartum bleeding 显示文摘HENRICH W SURBEK D KAINER F 2008J Perinat Med2008,36,6:1
5Preterm birth and the availability of cord blood for HPC transplantation 显示文摘Surbek DV Holzgreve W Steinmann C 2000Transfusion2000,40,:1
6Morphology assessed by transvaginal ultrasonography differs in patients in preterm labor with vs without bacterial aginosis显示文摘Surbek DV Hoeslie IM Holzgreve W 0,,15:1
7Diagnosis and treatment of peripartum bleeding显示文摘Henrich W Surbek D Kainer F 2008J Perinat Med2008,36,6:1
8Serum markers for predic- ting pre-eclampsia 显示文摘Baumann MU Bersinger NA Surbek DV 2007Mol Aspects Med2007,28,2:1
9Salt sensitity of children with low birth weight显示文摘Simonetti GD Raio L Surbek D 2008Hypertension2008,52,4:1
10Salt sensitivity of children with low birth weight显示文摘Simonetti GD Raio L Surbek D 2008Hypertension2008,52,4:1
11Placental mesenchymal stem cells as potential autologous graft for pre- and perinatal neuroregeneration显示文摘C. Bettina Portmann-Lanz Andreina Schoeberlein Alexander Huber Ruth Sager Antoine Malek Wolfgang Holzgreve Daniel V. Surbek 2006American Journal of Obstetrics and Gynecology2006,,3:1
12Serum markers for predicting pre-eclampsia显示文摘Marc U. Baumann Nick A. Bersinger Daniel V. Surbek 2007Molecular Aspects of Medicine2007,,2:1
13Salt sensitivity of children with low birth weight显示文摘Simonetti G D Raio L Surbek D 2008Hypertension2008,52,4:1
14Diagnosis and treatment of peripartum bleeding显示文摘Henrieh W Surbek D Kainer F 2008J Perinat Med2008,36,6:1
15Leukemia and pregnancy 显示文摘Fey Mf Surbek D 2008Recent Results Cancer Res2008,178,:1
16Diagnosis and treatment ofperipartum bleeding 显示文摘Henrich W Surbek D Kainer F 2008J Perinat Med2008,36,6:1
17Effect of preeclampsia on umbiUlcal cord blood hematopoietic progenitor-stem cells显示文摘Surbek DV Danzer E Steinmann C 2001Am J Obstet Gynecol2001,185,3:1
18Effect of preeclampsia on umbilical cord blood hematopoietic pro- genitorstemcells显示文摘SURBEK D DANZER E STEINMANN C 2001Am J Obstet Gynecol2001,185,2:1
19Serum markers for predicting preeelampsia 显示文摘Baumann MU Bersinger NA Surbek DS 2007Molecular Aspects of Medicine2007,28,2:1
20Serum markers for predicting pre - eclamp sia显示文摘Baumann MU Bersinger NA Surbek DV 2007Mol Aspecs Med2007,28,2:1
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