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| 1 | Gastroenterologist perceptions of faecal microbiota transplantation显示文摘AIM: To explore gastroenterologist perceptions towards and experience with faecal microbiota transplantation(FMT).METHODS: A questionnaire survey consisting of 17 questions was created to assess gastroenterologists' attitude towards and experience with FMT. This was anonymously distributed in hard copy format amongst attendees at gastroenterology meetings in Australia between October 2013 and April 2014. Basic descriptive statistical analyses were performed.RESULTS: Fifty-two clinicians participated. Twenty one percent had previously referred patients for FMT,8% more than once. Ninety percent would refer patients with Clostridium difficile infection(CDI) for FMT if easily available,37% for ulcerative colitis,13% for Crohn's disease and 6% for irritable bowel syndrome. Six percent would not refer any indication,including recurrent CDI. Eighty-six percent would enroll patients in FMT clinical trials. Thirty-seven percent considered the optimal mode of FMT administration transcolonoscopic,17% nasoduodenal,13% enema and 8% oral capsule. The greatest concerns regarding FMT were: 42% lack of evidence,12% infection risk,10% non infectious adverse effects/lack of safety data,10% aesthetic,10% lack of efficacy,4% disease exacerbation,and 2% inappropriate use; 6% had no concerns. Seventy seven percent believed there is a lack of accessibility while 52% had an interest in learning how to provide FMT. Only 6% offered FMT at their institution.CONCLUSION: Despite general enthusiasm,most gastroenterologists have limited experience with,or access to,FMT. The greatest concerns were lack of supportive evidence and safety issues. However a significant proportion would refer indications other than CDI for FMT despite insufficient evidence. These data provide guidance on where education and training are required. | Sudarshan Paramsothy Alissa J Walsh Thomas Borody Douglas Samuel Johan van den Bogaerde Rupert WL Leong Susan Connor Watson Ng Hazel M Mitchell Nadeem O Kaakoush Michael A Kamm | 2015 | World Journal of Gastroenterology2015，21，38： | 5 |
| 2 | Role of human papillomavirus in oropharyngeal squamous cell carcinoma: A review显示文摘Human papillomavirus(HPV) has been implicated in the pathogenesis of a subset of oropharyngeal squamous cell carcinoma. As a result, traditional paradigms in relation to the management of head and neck squamous cell carcinoma have been changing. Research into HPVrelated oropharyngeal squamous cell carcinoma is rapidly expanding, however many molecular pathological and clinical aspects of the role of HPV remain uncertain and are the subject of ongoing investigation. A detailed search of the literature pertaining to HPV-related oropharyngeal squamous cell carcinoma was performed and information on the topic was gathered. In this article, we present an extensive review of the current literature on the role of HPV in oropharyngeal squamous cell carcinoma, particularly in relation to epidemiology, risk factors, carcinogenesis, biomarkers and clinicalimplications. HPV has been established as a causative agent in oropharyngeal squamous cell carcinoma and biologically active HPV can act as a prognosticator with better overall survival than HPV-negative tumours. A distinct group of younger patients with limited tobacco and alcohol exposure have emerged as characteristic of this HPV-related subset of squamous cell carcinoma of the head and neck. However, the exact molecular mechanisms of carcinogenesis are not completely understood and further studies are needed to assist development of optimal prevention and treatment modalities. | Robbie SR Woods Esther M O'Regan Susan Kennedy Cara Martin John J O'Leary Conrad Timon | 2014 | World Journal of Clinical Cases2014，2，6： | 5 |
| 3 | Programming of appetite and type 2diabetes显示文摘 | Malgorzata S M Susan E O | 2005 | Early Human Development2005，81，12： | 1 |
| 4 | Volatile organic compounds (VOCs) emitted from 40 Mediterranean plant species: VOCs speciation and extrapolation to habitat scale 显示文摘 | Susan M O Christophe B Nicholas H C | 2001 | Atmospheric Environment2001，35，32： | 1 |
| 5 | Tumor Necrosis Factor α Is Toxic to Embryonic Mesencephalic Dopamine Neurons显示文摘 | Susan O McGuire Zao Dung Ling Jack W Lipton Caryl E Sortwell Timothy J Collier Paul M Carvey | 2001 | Experimental Neurology2001，，2： | 1 |
| 6 | Cir- cadian clock mutation disrupts estrous cyclicity and maintenance of pregnancy 显示文摘 | BROOKE H M SUSAN L O FRED W T | 2004 | Curt Biol2004，14，： | 1 |
| 7 | Age-dependent effects of trihexyphenidyl in extrapyramidal cerebral palsy显示文摘 | Alexander H Hoon Patricia O Freese Elsie M Reinhardt Mary Ann Wilson William T Lawrie Susan E Harryman Frank S Pidcock Michael V Johnston | 2001 | Pediatric Neurology2001，，1： | 1 |
| 8 | Randomised controlled trial of faecal-occult-blood screening for colorectal cancer显示文摘 | Jack D Hardcastle Jocelyn O Chamberlain Michael HE Robinson Susan M Moss Satya S Amar Tom W Balfour Peter D James Christine M Mangham | 1996 | The Lancet1996，，9040： | 1 |
| 9 | Update of the decitabine experience in higher risk myelodysplastic syndrome and analysis of prognostic factors associated with outcome 显示文摘 | Hagop M Kantarjian MD Susan O'Brien | 2007 | Cancer2007，109，2： | 1 |
| 10 | PKC- λ, is the atypical protein kinase C isoform: Expressed by immature ventricle 显示文摘 | Vitalyi O Peter M B Susan F S | 1997 | Am J Physiol1997，272，4： | 1 |
| 11 | Toxicologic studies in a fatal overdose of 2 ,4-D, MCPP and chlor-pyrifos 显示文摘 | JOHN O MARCELLO L SUSAN M P | 1983 | J Anal Toxicol1983，7，： | 1 |
| 12 | The effects of land-use constraints on housing pfces显示文摘 | Pollakowski H O Susan M | 1990 | LandEconomics1990，66，3： | 1 |
| 13 | Cost-effectiveness of MR imaging and core-needle biopsy in the preoperative work-up of suspicious breast lesions显示文摘 | Janie M H Curtis P L Susan G O | 1999 | Breast Imaging1999，213，1： | 1 |
| 14 | The Effects of Land-Use Constraints of Housing Prices显示文摘 | Pollakowski H O Susan M | 1990 | Land Economics1990，，3： | 1 |
| 15 | Comparision of aromatic and tertiary amine N-oxide of acridine DNA intercalaters as bioreductive drugs显示文摘 | Kevin O H Susan M P | 2000 | Biochemical Pharmacology2000，60，： | 1 |
| 16 | Early Results of a Chemoimmunotherapy Regimen of Fludarabine,Cyclophosphamide,and Rituximab As Initial Therapy for Chronic Lymphocytic Leukemia显示文摘 | MICHAEL J KEATING M J SUSAN O'BRIEN S | 2005 | Journal of Clinical Oncology2005，23，： | 1 |
| 17 | Implementa- tion of a stroke self- management program: A random- ized controued pilot study of veterans with stroke显示文摘 | Teresa M D Susan O Zhangsheng Y | 2011 | TBM2011，，1： | 1 |
| 18 | Serum estrogen and tumor-positive estrogen receptor-alpha are strong prognostic classifiers of non-small-cell lung cancer survival in both men and women 显示文摘 | Susan E O Leah E M Steen M | 2010 | Carcinogenesis2010，31，10： | 1 |
| 19 | Results of the Fludarabine and Cyclophosphamide Combination Regimen in Chronic Lymphocytic Leukemia显示文摘 | By Susan M O'Brien Hagop M | 2001 | J Clin Oncol2001，19，5： | 1 |
| 20 | Behavior of juvenile sablefish,Anoplopoma fimbria(Pallas),in a thermal gradient:Balancing food and temperature requirements显示文摘 | SUSAN M S BORI L O | 1998 | Journal of Experimental Marine Biology and Ecology1998，222，： | 1 |
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