| 1 | 念珠状发1例显示文摘患儿男,7岁。因枕部和头皮前半部丘疹伴脱发6年余,于2007年2月6日来我科就诊。患儿出生时毛发正常,数月后头发逐渐稀少,枕部和头皮前半部出现毛囊性角化性红色丘疹。头发一般在近头皮1cm处折断,头发最长不超过3cm。眉毛、睫毛及身体毳毛均正常。其父幼时亦有类似疾病,年龄增大后自行减轻。目前其父枕部头皮仍可见轻度毛囊性角化性丘疹。体格检查:发育正常,智力正常,各系统检查未见异常。 | Rudianto Sutarman 李惠 | 2008 | 临床皮肤科杂志2008，37，3： | 1 |
| 2 | Curcumin alters motor coordination but not total number of Purkinje cells in the cerebellum of adolescent male Wistar rats显示文摘OBJECTIVE: The present study aimed at investigating the effects of curcumin on the motor coordination and the estimate of the total number of cerebellar Purkinje cells of adolescent Wistar rats exposed to ethanol. METHODS: The total of 21 male Wistar rats aged 37 d old were divided into three groups, namely ethanol, ethanol-curcumin, and control groups. The ethanol group received 1.5 g/kg ethanol injected intraperitoneally and water given per oral; the ethanol-curcumin group received 1.5 g/kg ethanol injected intraperitoneally and curcumin extract given per oral; the control group received saline injection and oral water. The treatment was carried out daily for one month, after which the motor coordination performance of the rats was examined using revolving drum apparatus at test days 1, 8, and 15. The rats were finally sacrificed and the cerebellum of the rats was further processed for stereological analysis. The estimate of the total number of Purkinje cells was calculated using physical fractionator method. RESULTS: The ethanol-curcumin group performed better than both ethanol and control groups in the motor coordination ability at day 8 of testing (P< 0.01). No Purkinje cell loss was observed as a result of one month intraperitoneal injection of ethanol. CONCLUSION: Curcumin may exert beneficial effects on the motor coordination of adolescent rats exposed to ethanol via undetermined hormetic mechanisms. | Ginus Partadiredja Sutarman Taufik Nur Yahya Christiana Tri Nuryana Rina Susilowati | 2013 | Journal of Integrative Medicine2013，11，1： | 0 |
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