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| 1 | Critical analysis of feeding jejunostomy following resection of upper gastrointestinal malignancies显示文摘AIM To assess nutritional recovery,particularly regarding feeding jejunostomy tube(FJT)utilization,following upper gastrointestinal resection for malignancy. METHODS A retrospective review was performed of a prospectively-maintained database of adult patients who underwent esophagectomy or gastrectomy(subtotal or total)for cancer with curative intent,from January 2001 to June 2014. Patient demographics,the approach to esophagectomy,the extent of gastrectomy,FJT placement and utilization at discharge,administration of parenteral nutrition(PN),and complications were evaluated. All patients were followed for at least ninety days or until death.RESULTS The 287 patients underwent upper GI resection,comprised of 182 esophagectomy(n=107 transhiatal,58.7%; n=56 Ivor-Lewis,30.7%)and 105 gastrectomy [n=63 subtotal(SG),60.0%; n=42 total(TG),40.0%]. 181 of 182 esophagectomy patients underwent FJT,compared with 47 of 105 gastrectomy patients(99.5% vs 44.8%,P < 0.0001),of whom most had undergone TG(n=39,92.9% vs n=8 SG,12.9%,P < 0.0001). Median length of stay was similar between esophagectomy and gastrectomy groups(14.7 d vs 17.1 d,P=0.076). Upon discharge,87 esophagectomy patients(48.1%)were taking enteral feeds,with 53(29.3%)fully and 34(18.8%)partially dependent. Meanwhile,20 of 39 TG patients(51.3%)were either fully(n=3,7.7%)or partially(n=17,43.6%)dependent on tube feeds,compared with 5 of 8 SG patients(10.6%),all of whom were partially dependent. Gastrectomy patients were significantly less likely to be fully dependent on tube feeds at discharge compared to esophagectomy patients(6.4% vs 29.3%,P=0.0006). PN was administered despite FJT placement more often following gastrectomy than esophagectomy(n=11,23.4% vs n=7,3.9%,P=0.0001). FJT-specific complications requiring reoperation within 30 d of resection occurred more commonly in the gastrectomy group(n=6),all after TG,compared to 1 esophagectomy patient(12.8% vs 0.6%,P=0.0003). Six of 7 patients(85.7%)who experienced tube-related complications required PN.CONCLUSION Nutritional recovery following esophagectomy and gastrectomy is distinct. Operations are associated with unique complication profiles. Nutritional supplementation alternative to jejunostomy should be considered in particular scenarios. | Andrew M Blakely Saad Ajmal Rachel E Sargent Thomas T Ng Thomas J Miner | 2017 | World Journal of Gastrointestinal Surgery2017，9，2： | 4 |
| 2 | Anticipated Utility and Rational Expectations asApproximations of Bayesian Decision Making显示文摘 | CogleyT Sargent T | 2008 | International Eco-nomic Review2008，49，1： | 1 |
| 3 | Discounted linear exponential quadratic Gaussian control显示文摘 | Hansen L P Sargent T J | 1995 | IEEE Transactions on Automatic Control1995，40，5： | 1 |
| 4 | Regulation of epider real differentiation by a distal-less homeodomain gene显示文摘 | Morasso M I Markova N G Sargent T D | 1996 | The Journal of Cell Biology1996，135，6： | 1 |
| 5 | The Tat protein export pathway显示文摘 | Berks B C Sargent F Palmer T | 2000 | Molecular microbiology2000，35，2： | 1 |
| 6 | Robust permanent income and pricing显示文摘 | Hansen L P Sargent T J Tallarini T | 1999 | Review of Economic Studies1999，66，4： | 1 |
| 7 | Discounted linear exponential quadratic gaussian control 显示文摘 | HANSEN L P SARGENT T J | 1995 | IEEE Transactions on Automatic Control1995，40，5： | 1 |
| 8 | Robust permanent income and pricing with filtering显示文摘 | Hansen L P Sargent T J Wang N E | 2002 | Macroeconomic Dynamics2002，6，1： | 1 |
| 9 | A genetic linkage map of microsatellite, gene-spccific and morphological markers in diploid Fragaria 显示文摘 | Sargent D J Davis T M Tobutt K R | 2004 | Theor Appl Genet2004，109，： | 1 |
| 10 | An experimental study of the variation of wettability of SMDs using the micro-global wetting method 显示文摘 | Sargent P M Tang A C T Gordon F H | 1991 | IEEE/CHMT''91 IEMT Syrups1991，，： | 1 |
| 11 | Robustness and pricing with uncertain growth显示文摘 | Cagetti M Hansen L P Sargent T | 2002 | Review of Financial Studies2002，15，2： | 1 |
| 12 | Troplhoblast deportation in preeclamptic pregnancy显示文摘 | Chua S Wilkins T Sargent I | 1991 | Br J Obstef Gynecol1991，98，： | 1 |
| 13 | Some unpleasant monetarist arithmetic 显示文摘 | Sargent T J Wallace Neil | 1981 | Federal Reserve Bank of Minneapolis Quarterly Review1981，，1： | 1 |
| 14 | Evaluation of commercial precooiing for sweet corn 显示文摘 | Talbot M T Sargent S A Brecht J K | 1990 | Proceeding of the Florida State Horticultural society1990，102，： | 1 |
| 15 | Some Unpleasant Monetarist Arithmetic显示文摘 | Sargent T J Wallace N | 1981 | The Federal Reserve Bank of Minneapolis Quarterly Review1981，，3： | 1 |
| 16 | Randomized trial of glyceropho SPae-supplemented infant formuala to prevent lead absorption显示文摘 | Sargent J D Dalton M A O/Connor G T | 1999 | AMJ Clin1999，69，6： | 1 |
| 17 | Evaluation of com- mercial precooling for sweet corn 显示文摘 | Talbot M T Sargent S A Brecht J K | 1990 | Proceeding of the Florida State Horticuhural Society1990，102，： | 1 |
| 18 | Mortality associated with daily bolus 5-fluorouracil/leucovorin administered in combination with either irinotecan or oxaliplatin: results from Intergroup Trial N9741显示文摘 | Delaunoit T Goldberg RM Sargent DJ | 2004 | Cancer2004，101，10： | 1 |
| 19 | Some unpleasant monetarist arithmetic显示文摘 | T Sargent N Wallace | 1981 | Federal Reserve Bank of Minneapolic Quarterly Review1981，，5： | 1 |
| 20 | Mortality associated with daily bolus 5-fluorouracil/leucovorin administered in combination with either irinotecan or oxaliplatin:results from Intergroup TrialN9741显示文摘 | Delaunoit T Goldberg RM Sargent DJ | 2004 | Cancer2004，101，10： | 1 |
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