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| 1 | Prognostic factors in patients with advanced cholangiocarcinoma: Role of surgery, chemotherapy and body mass index显示文摘AIM: To study the factors that may affect survival of cholangiocarcinoma in Lebanon. METHODS: A retrospective review of the medical records of 55 patients diagnosed with cholangio- carcinoma at the American University of Beirut between 1990 and 2005 was conducted. Univariate and multivariate analyses were performed to determine the impact of surgery, chemotherapy, body mass index, bilirubin level and other factors on survival. RESULTS: The median survival of all patients was 8.57 mo (0.03-105.2). Univariate analysis showed that low bilirubin level (< 10 mg/dL), radical surgery and chemotherapy administration were significantly associated with better survival (P = 0.012, 0.038 and 0.038, respectively). In subgroup analysis on patients who had no surgery, chemotherapy administration prolonged median survival significantly (17.0 mo vs 3.5 mo, P = 0.001). Multivariate analysis identifiedonly low bilirubin level < 10 mg/dL and chemotherapy administration as independent predictors associated with better survival (P < 0.05). CONCLUSION: Our data show that palliative and postoperative chemotherapy as well as a bilirubin level < 10 mg/dL are independent predictors of a significant increase in survival in patients with cholangiocarcinoma. | Mirna H Farhat Ali I Shamseddine Ayman N Tawil Ghina Berjawi Charif Sidani Wael Shamseddeen Kassem A Barada | 2008 | World Journal of Gastroenterology2008，14，20： | 9 |
| 2 | Effect of mucin production on survival in colorectal cancer:A case-control study显示文摘AIM: To investigate the impact of mucin production on prognosis in colorectal cancer, in terms of overall survival (OS) and time to disease progression (TTP) in patients with mucinous compared to those with non-mucinous colorectal cancer (NMCRC), matched for age, gender, and tumor stage.METHODS: Thirty five patients with mucinous colorectal cancer (MCRC) were matched for age, gender, and tumor stage with 35 controls having NMCRC. OS and TTP were compared among 4 groups divided according to mucin content: group A (50%-75% mucin), group B (75%-100% mucin), group C or controls (< 50% mucin). Group D consisted of all patients with tumors having < 75% mucin (controls and groups A together).RESULTS: Median survival in MCRC and NMCRC groups was 46.2 and 112.9 mo, respectively (P = 0.26). OS in groups A and B was 70.1 and 32.8 mo (P = 0.46), and in groups B and D was 32.8 and 70.1 mo, respectively (P = 0.143). TTP in MCRC and NMCRC was 50.17 and 44.77 mo, respectively (P = 0.795). TTP in groups A, B, and D was 70.1, 24.8, and 65.5 mo, respectively. Twenty-eight percent of patients with MCRC had poorly differentiated adenocarcinoma versus 8.6% in NMCRC patients (P = 0.028).CONCLUSION: MCRC is associated with a non-significant decrease in median survival and TTP, particularlywhen mucin content is > 75% of tumor volume. However, it tends to be more poorly differentiated. A larger study matching for stage and grade is needed. | Mirna H Farhat Kassem A Barada Ayman N Tawil Doha M Itani Hassan A Hatoum Ali I Shamseddine | 2008 | World Journal of Gastroenterology2008，14，45： | 6 |
| 3 | Oxidation behavior of 2D and 3D carbon/carbonthermostructural materials protected by CVD polylayer coatings显示文摘 | GOUJARD S VANDENBULCKE L TAWIL H | 1994 | Thin SolidFilms1994，252，2： | 1 |
| 4 | Oxidation behaviour of two-and three-dimensional C/SiC thermostructural materials protected by chemical- vapour-deposition polylayers coatings 显示文摘 | Goujard S Vandenbulcke L Tawil H | 1994 | Journal of Materials Science1994，29，23： | 1 |
| 5 | Oxidation behavior of 2D and 3D carbon/carbon thermostructural materials protected by CVD polylayer coatings 显示文摘 | Goujard S Vandenbulcke L Tawil H | 1994 | Thin Solid Films1994，252，2： | 1 |
| 6 | An adenovirus en- coding proapoptotic Bax synergistically radiosnsitizes malignant glioma显示文摘 | Ararat WO Buchsbaum DJ G6mez - Navarro J Tawil SA Olsen C Xiang J El- Akad H Salama AM Badib AO Stackhouse MA Curiel DT | 2003 | Int J Radiat Oncol Biol Phys2003，55，4： | 1 |
| 7 | Modulation of 3D fibrin matrix stiffness by intrinsic fibrinogen-thrombin compositions and by extrinsic cellular activity显示文摘 | Duong H Wu B Tawil B | 2009 | Tissue Eng Part A2009，15，7： | 1 |
| 8 | Thermal diffusivity of chemically vapor deposited silicon carbide reinforced with silicon carbide or carbon fibers 显示文摘 | Tawil H Bentsen L D Baskaran S | 1985 | J Mater Sci1985，20，： | 1 |
| 9 | Periosteal osteoblastoma of the calvaria mimicking a meningioma显示文摘 | Tawil A Comair Y Nasser H | 2008 | Pathol Res Pratt2008，204，6： | 1 |
| 10 | Scalable service-oriented replication with flexible consistency guarantee in the cloud显示文摘 | Chen Tao Bahsoon R Tawil A-R H | 2014 | Information Sciences2014，4，： | 1 |
| 11 | Oxidation behavior of 2D and 3D carbon/carbon thermostructural materials protected by CVD polylayer coatings 显示文摘 | Goujard S Vandenbulcke L Tawil H | 1994 | Thin Solid Films1994，252，2： | 1 |
| 12 | Oxidation tests of carbonaceous composite materials protected by Si B C CVDcoatings 显示文摘 | Goujard S Vandenbulcke I Tawil H | 1994 | Thin Solid Films1994，245，12： | 1 |
| 13 | Risk factors, characteristics and outcomes of necrotizing enterocolitis in late preterm and term infants 显示文摘 | A1 Tawil K Sumaily H Ahmed IA | 2013 | J Neonatal Perinatal ivied2013，6，2： | 1 |
| 14 | Modulation of 3D fibrin matrix stiffness by intrinsic fibrinogen-thrombin compositions and by extrinsic cellular activity显示文摘 | Duong H Wu B Tawil B | 2009 | Tissue Eng Part A2009，15，7： | 1 |
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