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| 1 | 认知行为团体咨询对大学生抑郁症状的干预效果显示文摘目的:探讨认知行为团体咨询对大学生抑郁症状的干预效果。方法:于2013年3月和9月共招募存在轻中度抑郁症状的大学生80名[Beck抑郁问卷第二版(BDI-II)得分为5≤BDI-II<21],将其随机分至干预组(n=40)或对照组(n=40),干预组接受为期8周的认知行为团体咨询,对照组在干预期和追踪期不接受任何处理。在基线水平、8周干预后及随访3个月末通过BDI-II、生活满意度问卷(LSR)、大学生解释风格问卷(ESQ)及社会问题解决问卷中文版(C-SPIS)来评估干预效果。结果:BDI-II、LSR、消极解释风格(CN)、消极问题定向(NPO)以及积极问题定向(PPO)评分的分组与时间的交互效应均有统计学意义(均P<0.05)。进一步简单效应分析表明:基线水平,两组各量表得分差异均无统计学意义(均P<0.05);8周干预后,干预组的BDI-II得分低于对照组[(6.6±3.1)vs.(10.3±4.1),P<0.001];随访3个月末,干预组的BDI-II、CN、NPO得分均低于对照组[(4.5±2.2)vs.(12.6±4.6),(12.2±1.2)vs.(14.9±1.2),(12.8±2.5)vs.(16.9±2.8),均P<0.05],而LSR和PPO得分均高于对照组[(4.3±0.9)vs.(3.5±1.0),(18.3±2.7)vs.(16.7±2.0),均P<0.05]。结论:认知行为团体咨询能有效降低抑郁症状,促进解释风格的积极转变,并提升问题解决能力,增进生活满意度。 | 杨燕 杨冉明 林潇骁 肖晶 OEI Tian Po 崔丽霞 | 2014 | 中国心理卫生杂志2014，28，12： | 13 |
| 2 | Propofol differentially induces unconsciousness and respiratory depression through distinct interactions between GABAa receptor and GABAergic neuron in corresponding nuclei显示文摘Propofol is the most commonly used intravenous anesthetic worldwide.It can induce loss of consciousness prior to the occurrence of severe respiratory suppression,which is also a pharmacodynamic feature of all general anesthetics.However,the neural mechanisms underlying this natural phenomenon are controversial and highly related to patient safety.In the present study,we demonstrated that the pharmacodynamic effects of propofol(50 and 100 μM)on suppression of consciousness-related excitatory postsynaptic currents in the medial prefrontal cortex(mPFC)and centromedian nucleus of the thalamus(CMT)were lower than those in the kernel respiratory rhythmogenesis nucleus pre-Botzinger complex(PrBo).Furthermore,we unexpectedly found that the GABAa receptor β3 subunit is the key target for propofol's action and that it is mutually and exclusively expressed in GABAergic neurons.It is also more abundant in the mPFC and CMT,but mainly co-localized with GABAergic neurons in the PrBo.As a result,the differentiated expression pattern should mediate more neuron suppression through the activation of GABAergic neurons in the mPFC and CMT at low doses of propofol(50 μM).However,PrBo GABAergic neurons were only activated by propofol at a high dose(100 μM).These results highlight the detailed pharmacodynamic effects of propofol on consciousness-related and respiration-related nuclei and provide the distinct interaction mechanism between the β3 subunit and GABAergic neurons in mediating the suppression of consciousness compared to the inhibition of respiration. | Junli Jiang Yingfu Jiao Po Gao Wen Yin Wei Zhou Yunchun Zhang Yanjun Liu Daxiang Wen Yuan Wang Liang Zhou Tian Yu Weifeng Yu | 2021 | Acta Biochimica et Biophysica Sinica2021，53，8： | 11 |
| 3 | Stk2,a Mitogen-Activated Protein Kinase from Setosphaeria turcica,Specifically Complements the Functions of the Fus3 and Kss1 of Saccharomyces cerevisiae in Filamentation,Invasive Growth,and Mating Behavior显示文摘Setosphaeria turcica,an essential phytopathogenic fungus,is the primary cause of serious yield losses in corn;however,its pathogenic mechanism is poorly understood.We cloned STK2,a newly discovered mitogen-activated protein kinase gene with a deduced amino acid sequence that is 96%identical to MAK2 from Phaeosphaeria nodorum,56%identical to KSS1 and 57%identical to FUS3 from Saccharomyces cerevisiae.To deduce Stk2 function in S.turcica and to identify the genetic relationship between STK2 and KSS1/FUS3 from S.cerevisiae,a restructured vector containing the open reading frame of STK2 was transformed into a fus3/kss1 double deletion mutant of S.cerevisiae.The results show that the STK2complementary strain clearly formed pseudohyphae and ascospores,and the strain grew on the surface of the medium after rinsing with sterile water and the characteristics of the complementary strain was the same as the wild-type strain.Moreover,STK2 complemented the function of KSS1 in filamentation and invasive growth,as well as the mating behavior of FUS3 in S.cerevisiae,however,its exact functions in S.turcica will be studied in the future research. | GU Shou-qin YANG Yang LI Po ZHANG Chang-zhi FAN Yu ZHANG Xiao-yu TIAN Lan HAO Zhi-min CAO Zhi-yan GONG Xiao-dong FAN Yong-shan HAN Jian-min DONG Jin-gao | 2013 | Journal of Integrative Agriculture2013，12，12： | 3 |
| 4 | Discovery and demonstration of small circular DNA molecules derived from Chinese tomato yellow leaf curl virus显示文摘Tomato yellow leaf curl viruses belong to Begomoviruses of geminiviruses. In this work, we first found and demonstrated that the small circular DNA molecules were derived from Chinese tomato yellow leaf curl viruses (TYLCV-CHI). These small circular DNA molecules are about 1.3 kb, which are half the full-length of TYLCV-CHI DNA A. It was shown by sequence determination and analysis that there was unknown-origin sequence insertion in the middle of the small molecules. These sequences of unknown-origin were neither homologous to DNA A nor to DNA B, and were formed by recombination of virus DNA and plant DNA. Although various defective molecules contained different unknown-origin sequence insertion, all the molecules contained the intergenic region and part of the AC1 (Rep) gene. But they did not contain full ORF. | YIN Qinyan ZHANG Ying ZHANG Yuman LIU Yule ZHANG Zhongze TIAN Po | 2000 | Chinese Science Bulletin2000，45，15： | 2 |
| 5 | Gambling among the Chinese: A comprehensive review显示文摘 | Jasmine M.Y. Loo Namrata Raylu Tian Po S. Oei | 2008 | Clinical Psychology Review2008，，7： | 1 |
| 6 | Financial Development and Innovation: Cross - country Evidence显示文摘 | Po - Hsuan Hsu Xuan Tian Yan Xu | 2014 | Journal of Fi- nancial Economics2014，112，1： | 1 |
| 7 | Financial Develop- ment and Innovation : Cross - country Evidence 显示文摘 | Po - Hsuan Hsu Xuan Tian and Yan Xu | 2014 | Journal of Financial Economics2014，112，1： | 1 |
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