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74篇 您的检索式：作者名="Tabor S"

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	题名	作者	年代	出处	被引量
1	Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source显示文摘BACKGROUND The trans-fat containing AMLN(amylin liver non-alcoholic steatohepatitis,NASH)diet has been extensively validated in C57BL/6J mice with or without the Lep^ob/Lep^ob(ob/ob)mutation in the leptin gene for reliably inducing metabolic and liver histopathological changes recapitulating hallmarks of NASH.Due to a recent ban on trans-fats as food additive,there is a marked need for developing a new diet capable of promoting a compatible level of disease in ob/ob and C57BL/6J mice.AIM To develop a biopsy-confirmed mouse model of NASH based on an obesogenic diet with trans-fat substituted by saturated fat.METHODS Male ob/ob mice were fed AMLN diet or a modified AMLN diet with trans-fat(Primex shortening)substituted by equivalent amounts of palm oil[Gubra amylin NASH,(GAN)diet]for 8,12 and 16 wk.C57BL/6J mice were fed the same diets for 28 wk.AMLN and GAN diets had similar caloric content(40%fat kcal),fructose(22%)and cholesterol(2%)level.RESULTS The GAN diet was more obesogenic compared to the AMLN diet and impaired glucose tolerance.Biopsy-confirmed steatosis,lobular inflammation,hepatocyte ballooning,fibrotic liver lesions and hepatic transcriptome changes were similar in ob/ob mice fed the GAN or AMLN diet.C57BL/6J mice developed a mild to moderate fibrotic NASH phenotype when fed the same diets.CONCLUSION Substitution of Primex with palm oil promotes a similar phenotype of biopsyconfirmed NASH in ob/ob and C57BL/6J mice,making GAN diet-induced obese mouse models suitable for characterizing novel NASH treatments.	Michelle L Boland Denise Oro Kirstine S T■lb■l Sebastian T Thrane Jens Christian Nielsen Taylor S Cohen David E Tabor Fiona Fernandes Andrey Tovchigrechko Sanne S Veidal Paul Warrener Bret R Sellman Jacob Jelsing Michael Feigh Niels Vrang James L Trevaskis Henrik H Hansen	2019	World Journal of Gastroenterology2019，25，33：	3
2	The wear of filled polytetrafluoroethylene 显示文摘	Bahadur S Tabor D	1984	Wear1984，94，1：	2
3	Escherichia coli thiore- doxin confers processivity on the DNA polymerase activity of the gene 5 protein of bacteriophage T7 显示文摘	TABOR S HUBER H E RICHARDSON C C	1987	J Biol Chem1987，262，16：	1
4	Acid cleavable PEG-lipids for applications in a ternary gene delivery vector 显示文摘	Wong J B Grosse S Tabor A B	2008	Mol Biosys2008，4，6：	1
5	Electromagnetic Propagation through materials Possessing both Faraday rotation and birefringence:experiments with Ytterbium Qrthoferrite显示文摘	W J Tabor F S Chen		0，，07：	1
6	Narrowing the distance:Implementing a hybrid learning mod- el 显示文摘	TABOR S W	2007	Quarterly Review of Distance Education2007，8，1：	1
7	Adhesion of solids and the effect of surface films显示文摘	McFARLANE J S TABOR D	1950	Proc R Soc Lond A1950，202，：	1
8	DNA sequence analysis with a modified bacteriophage T7 DNA polymerase显示文摘	Tabor S Richardson C C	1985	Proc Natl Acad Sci USA1985，82，：	1
9	Electron density matching as a guide to surfactant design 显示文摘	TABOR R F GOLD S EASTOE J	2006	Langmuir2006，22，3：	1
10	The wear of filled PE显示文摘	Bahadur S Tabor D	1984	Wear1984，98，：	1
11	The wear of filled polytetrafluoroethylene显示文摘	Bahadur S Tabor D	1984	Wear1984，98，：	1
12	The wear of filled polytetrafluoroethylene显示文摘	Bahadur S Tabor K	1984	Wear1984，98，：	1
13	RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement显示文摘	Lau C M Broughton C Tabor A S	2005	J Exp Med2005，202，9：	1
14	Functional frontalisation with age: mapping neuron developmental trajecatories with fMRI显示文摘	Rubia K Overmeyer S Tabor E	2000	Neurosci Biobehav Rev2000，24，1：	1
15	The thioredoxin binding domain of bacteriophage T7 DNA polymerase confers processivity on Escherichia coli DNA polymerase I 显示文摘	Bedford E Tabor S Richardson C C	1997	Proc Natl Acad Sci USA1997，94，2：	1
16	Barophilic growth of bacteria from intestinal tracts of deep-sea invertebrates显示文摘	DEMING J W TABOR P S COLWELL R R	1981	Microbial ecology1981，7，1：	1
17	The wear of filled polytetrafluoroethylene显示文摘	Bahadur S Tabor D	1984	Wear1984，98，：	1
18	A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specicic genes显示文摘	Tabor S Richardson CC		0，，：	1
19	Middle Miocene paleoaltimetry of southern Tibet : Implications for the role of mantle thickening and delamination in the Himalayan orogen 显示文摘	Currie B S Rowley D B Tabor N J	2005	Geology2005，33，：	1
20	RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement显示文摘	Lau C M Broughton C Tabor A S		0，，09：	1

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