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| 1 | Autoantibody profiles in autoimmune hepatitis and chronic hepatitis C identifies similarities in patients with severe disease显示文摘AIM To determine how the auto-antibodies(Abs) profiles overlap in chronic hepatitis C infection(CHC) and autoimmune hepatitis(AIH) and correlate to liver disease.METHODS Levels of antinuclear Ab, smooth muscle antibody(SMA) and liver/kidney microsomal-1(LKM-1) Ab and markers of liver damage were determined in the sera of 50 patients with CHC infection, 20 AIH patients and 20 healthy controls using enzyme linked immunosorbent assay and other immune assays. RESULTS We found that AIH patients had more severe liver disease as determined by elevation of total Ig G, alkaline phosphatase, total serum bilirubin and serum transaminases and significantly higher prevalence of the three non-organ-specific autoantibodies(auto-Abs) than CHC patients. Antinuclear Ab, SMA and LKM-1 Ab were also present in 36% of CHC patients and related to disease severity. CHC cases positive for auto-Abs were directly comparable to AIH in respect of most markers of liver damage and total Ig G. These cases had longer disease duration compared with auto-Ab negative cases, but there was no difference in gender, age or viral load. KLM-1+ Ab CHC cases showed best overlap with AIH. CONCLUSION Auto-Ab levels in CHC may be important markers of disease severity and positive cases have a disease similar to AIH. Auto-Abs might have a pathogenic role as indicated by elevated markers of liver damage. Future studies will unravel any novel associations between these two diseases, whether genetic or other. | Kawa Amin Aram H Rasool Ali Hattem Taha AM Al-Karboly Taher E Taher Jonas Bystrom | 2017 | World Journal of Gastroenterology2017，23，8： | 5 |
| 2 | Thalassemia inter- media: Revisited显示文摘 | Taher A Isma'eel H Cappellinin MD | 2006 | Blood Cells Mol Dis2006，37，1： | 1 |
| 3 | Thalassemia intermedia:revisited显示文摘 | Taher A Isma'eel H Cappellini MD | 2006 | Blood Cells Mol Dis2006，37，： | 1 |
| 4 | Menopausal age, re-lated factors and climacteric symptoms in Libyan women显示文摘 | Taher Y A Ben Emhemed H M Tawati A M | 2012 | Cli-macteric2012，16，1： | 1 |
| 5 | Kinetic aspects of bacterial cellulose formation in nata - de - coco culture system 显示文摘 | BUDHIONO A ROSIDI B TAHER H | 1999 | Carbohyd Polym1999，40，： | 1 |
| 6 | Growth characteristics and biomass production of kenaf 显示文摘 | TAHER Y Y SHUKOR N A A ABDUL-HAMID H | 2011 | African Journal of Biotechnology2011，10，13： | 1 |
| 7 | Effective extraction of microalgae lipids from wet biomass for biodiesel production显示文摘 | Taher H A1-Zuhair S A1-Marzouqi AH | 2014 | Biomass Bioenergy2014，66，： | 1 |
| 8 | Gamification: A New Paradigm for Online User Engagement显示文摘 | Kankanhalli A Taher M Cavusoglu H | 2012 | 2012，，： | 1 |
| 9 | Exact solutions for free flexural vibration of Lovy- type rectangular thick plates via third-order shear deformation plate theory 显示文摘 | Hosseini-HashemiS Fadaee M Taher H R D | 2011 | Appl Math Mod2011，35，2： | 1 |
| 10 | Transplantation of expanded bone marrow-derived very smal embryonic-like stem cells (VSEL-SCs) improves left ventricular function andremodeling after myocardial infarction显示文摘 | Zuba-Surma EK Guo Y Taher H | | 0，，06： | 1 |
| 11 | Use of nanoporous Cu (11) ion imprinted polymer as a new sorbent for preconcentration of Cu (11) in water, biological, and agricultural samples and its determination by electrothermal atomic absorption spectrometry显示文摘 | Fazelirad H Taher M A Ashkenani H | 2014 | J AOAC Int2014，97，4： | 1 |
| 12 | Exact acoustical analysis of vibrating rectangular plates with two opposite edges simply supported via Mindlin plate theory显示文摘 | HASHEMI S H KHORSHIDI K TAHER H R D | 2009 | Journal of Sound and Vibration2009，322，45： | 1 |
| 13 | Prevalence of Throm-boembolic Events among 8,860 Patients with ThalassemiaMajor and Intermedia in the Mediterranean Area and Iran显示文摘 | Taher A Isma eel H Mehio G | 2006 | Thromb Haemost2006，96，4： | 1 |
| 14 | Prevalence of throm- boembolic events among 8 860 patients with thalassaemia major and intermedia in the Mediterranean area and Iran 显示文摘 | Taher A Ismaeel H Mehio G | 2006 | Thromb Haemost2006，96，3： | 1 |
| 15 | Simultaneous column preconcentration of ultra-trace amounts of heavy metals with nanoadsorbent in some environmental and biological samples显示文摘 | Fazelirad H Taher M A | 2015 | Environ Technol2015，37，3： | 1 |
| 16 | Topic-sensitive pagerank: a context-sensitive ranking algorithm for websearch显示文摘 | Taher H Haveliwala | 2003 | IEEE Trans Knowl Data Eng2003，15，4： | 1 |
| 17 | α,β-unsaturated aldehydes and ketones in the oxidation of limonene with selenium dioxide显示文摘 | TAHER H A UBIERGO G O | 1982 | Essenzo Deriv Agrum(Span)1982，52，： | 1 |
| 18 | Carbamazepine-induced thrombocytopenia显示文摘 | TAHER A T ARABI M SIBAI H | 2012 | Blood Cells Mol Dis2012，48，3： | 1 |
| 19 | Thalassemia intermedia : revisited 显示文摘 | Taher A Ismaeel H Cappellini MD | 2006 | Blood Cells Mol Dis2006，37，1： | 1 |
| 20 | Prevalence of thromboembolic events among 8,860 patients with thalassaemia major and intermedia in the Mediterranean area and Iran显示文摘 | Taher A Isma'eel H Mehio G | 2006 | Thrombosis and Haemostasis2006，96，4： | 1 |
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