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| 1 | Prediction of lymph node metastasis and sentinel node navigation surgery for patients with early-stage gastric cancer显示文摘Accurate prediction of lymph node(LN) status is crucially important for appropriate treatment planning in patients with early gastric cancer(EGC). However,consensus on patient and tumor characteristics associated with LN metastasis are yet to be reached. Through systematic search,we identified several independent variables associated with LN metastasis in EGC,which should be included in future research to assess which of these variables remain as significant predictors of LN metastasis. On the other hand,even if we use these promising parameters,we should realize the limitation and the difficulty of predicting LN metastasis accurately. The sentinel LN(SLN) is defined as first possible site to receive cancer cells along the route of lymphatic drainage from the primary tumor. The absence of metastasis in SLN is believed to correlate with the absence of metastasis in downstream LNs. In this review,we have attempted to focus on several independent parameters which have close relationship between tumor and LN metastasis in EGC. In addition,we evaluated the history of sentinel node navigation surgery and the usefulness for EGC. | Atsuo Shida Norio Mitsumori Hiroshi Nimura Yuta Takano Taizou Iwasaki Muneharu Fujisaki Naoto Takahashi Katsuhiko Yanaga | 2016 | World Journal of Gastroenterology2016，22，33： | 13 |
| 2 | Impact of lipoprotein lipase gene polymorphisms on ulcerative colitis显示文摘AIM: To examine the influence of lipoprotein lipase (LPL) gene polymorphism in ulcerative colitis (UC) patients. METHODS: Peripheral blood was obtained from 131 pa- tients with UC and 106 healthy controls for DNA extrac- tion. We determined LPL gene polymorphisms affecting the enzyme at Ser447stop, as well as HindⅢ and Pvu Ⅱ polymorphisms using PCR techniques. PCR products were characterized by PCR-RFLP and direct sequencing. Polymorphisms were examined for association with clini- cal features in UC patients. Genotype frequencies for LPL polymorphisms were also compared between UC patients and controls. RESULTS: In patients with onset at age 20 years or younger, C/G and G/G genotypes for Ser447stop poly- morphism were more prevalent than C/C genotype (OR = 3.13, 95% CI = 0.95-10.33). Patients with H+/- or H-/-genotype for HindⅢ polymorphism also were more nu- merous than those with H+/+ genotype (OR = 2.51, 95% CI = 0.85-7.45). In the group with H+/+ genotype for HindⅢ polymorphism, more patients had serum triglyc- eride concentrations over 150 mg/dL than patients with H+/- or H-/- genotype (P < 0.01, OR = 6.46, 95% CI = 1.39-30.12). Hypertriglycemia was also more prevalent in patients with P+/+ genotypes for PvuⅡ polymorphism (P < 0.05, OR = 3.0, 95% CI = 1.06-8.50). Genotype fre- quency for LPL polymorphism did not differ significantly between UC patients and controls. CONCLUSION: Ser447stop and HindⅢ LPL polymor- phisms may influence age of onset of UC, while HindⅢ and PvuⅡ polymorphisms influence serum triglyceride in UC patients. | Toshihito Kosaka Junji Yoshino Kazuo Inui Takao Wakabayashi Kazumu Okushima Takashi Kobayashi Hironao Miyoshi Yuta Nakamura Shigekazu Hayashi Taizou Shiraishi Masatoshi Watanabe Takayuki Yamamoto Ai Nakahara Takahiko Katoh | 2006 | World Journal of Gastroenterology2006，12，39： | 3 |
| 3 | Applicability of headspace solid-phase microextraction to the determination of multi-class pesticides in waters显示文摘 | Mitsushi Sakamoto Taizou Tsutsumi | 2003 | Journal of Chromatography A2003，，1： | 1 |
| 4 | Applicability of headspace solid--phase microextraction to the determination of multi- class pesticides in waters显示文摘 | Sakamoto Mitsushi Tsutsumi Taizou | 2004 | Journal of Chromatography A2004，1028，1： | 1 |
| 5 | Left Ventricular Strain and Transmural Distribution of Structural Remodeling in Hypertensive Heart Disease显示文摘 | Tomoko Ishizu Yoshihiro Seo Yuri Kameda Ryo Kawamura Taizou Kimura Nobutake Shimojo Dongzhu Xu Nobuyuki Murakoshi Kazutaka Aonuma | 2014 | Hypertension2014，，3： | 1 |
| 6 | Effect of retinoblastoma tumor suppressor gene expression on chemosensitivityof human osteosarcoma cell lines显示文摘 | Koji Iida Tsutomu Nobori Akihiko Matsumine Akihiko Isaka Masashi Seto Taizou Shiraishi Atsumasa Uchida | 2003 | Oncology Reports2003，，6： | 1 |
| 7 | Applicability of head-space solida-phase microextraction to the determination of multi-class pesticides in waters显示文摘 | Sakamoto Mitsushi Tsutsumi Taizou | 2004 | Journal of Chromatography A2004，1028，1： | 1 |
| 8 | Synthesis of helical polyacetylene in chiral nematic liquid crystals uising crown ether type binaphthyal derivatives as chiral dopants显示文摘 | Kazuo Akagi Guo Shouxue Taizou Mori | 2005 | J Am Chem Soc2005，127，14： | 1 |
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