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| 1 | In vivo anti-salmonella activity of aqueous extract of Euphorbia prostrata Aiton(Euphorbiaceae) and its toxicological evaluation显示文摘Objective: To investigate the in vivo anti-salmonella activity and the safety of aqueous extract of Euphorbia prostratra(E. prostratra), a plant commonly used in Cameroon by traditional healers.Methods: A Salmonella typhimurium-infected rat model was used for the study. The physiological, biochemical and histopathological markers of possible side effects of this extract were studied using standard methods.Results: The extract had a significant effect on the number of viable Salmonella typhimurium recovered from faeces, and could stop salmonellosis after 8 and 10 days of treatment for male and female rats, respectively, with non-toxic doses. However, the biochemical and histopathological analyses revealed that at relatively high doses(≥ 73.48 mg/kg for female and ≥ 122.71 mg/kg for male) the extract could induce liver damage, as illustrated by a rise of serum transaminases' levels and significant inflammation of the parenchyma and portal vein.Side effects were also observed on the kidneys, as shown by both serum and urinary creatinine,and urinary proteins.Conclusions: The overall results indicate that the aqueous extract of E. prostrata has the potential to provide an effective treatment for salmonellosis, including typhoid fever. However,it is necessary to extrapolate these results in large animals, in further studies. | Donald Sédric Tala Donatien Gatsing Siméon Pierre Chegaing Fodouop Charles Fokunang Fabrice Kengni Merline Namekong Djimeli | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，4： | 3 |
| 2 | Knowledge Building Expertise: Nanomodellers' Education as an Example显示文摘 | Tala S | 2012 | Science & Education2012，124，： | 1 |
| 3 | Role of synthesized organoselenium compounds on protection of rat erythro- cytes from DMBA-induced oxidative stress 显示文摘 | Talas S Z Yilmaz I Ozdemir I | 2009 | Biological Trace Element Research2009，128，2： | 1 |
| 4 | Synthesis and antimicrobial activity of some new cyanopyridine and cyanopyrans towards Myco- bacterium tuberculosis and other microorganisms 显示文摘 | Vyas D H Tala S D Akbari J D | 2009 | Indian Jour- nal of Chemistry B2009，48，6： | 1 |
| 5 | Blunt and penetrating object injuries in housekeepers working in a Turkish University Hospital显示文摘 | Erdem Y Tala M S | 2006 | Am J Infect Control2006，34，4： | 1 |
| 6 | Antioxidative role of selenium on some tissues of( Ed^2 + , Cr^3 + ) - induced rainbow trout 显示文摘 | Orun I Talas Z S Ozdemir I | 2008 | Ecotoxicotogy and Environmental Safety2008，71，1： | 1 |
| 7 | Plasmacytomaof the temporal bone:management with a combination of surgery and radiotherapy显示文摘 | YETISER S TALAS D AKKAYA A | 2001 | Acta Otolaryngol2001，121，： | 1 |
| 8 | Occupational Exposure to Blood and Body Fluids among Turkish Nursing Students during Clinical Practice Training:Frequency of Needlestick/Sharp Injuries and Hepatitis B Immunization显示文摘 | Talas M S | 2009 | J Clin Nurs2009，18，10： | 1 |
| 9 | Synthesis of Ssome new 1,2,3,4 - Tetrahydropyrimidine - 2 - thiones and their thiazolo pyrimidine derivatives as potential biological agents显示文摘 | Akbari J D Kachhadia P K Tala S D | 2008 | Phosphorus Sulfur Silicon and the Related Elements2008，183，8： | 1 |
| 10 | Functional status in Turkish women with gynecological cancer显示文摘 | Akkuzu G Talas M S Ortac F | 2013 | Asian Pacific journal of cancer prevention : APJCP2013，15，20： | 1 |
| 11 | Effects of sodiumselenite on some biochemical and hematological parameters ofrainbow trout (Oncorhynchus mykiss Walbaum, 1792) exposed toPb2t and Cu2+显示文摘 | Ates B Orun I Talas Z S Durmaz G | 2008 | Fish Physiol Biochem2008，34，： | 1 |
| 12 | Antioxidative role of selenium on some tissues of(Cd2+,Cr3+)-induced rainbowtrout显示文摘 | Orun I Talas Z S Ozdemir I | 2008 | Ecotoxicology and Environmental Safety2008，71，1： | 1 |
| 13 | The Assessment of Carbon Equivalent Formulas in Predicting the Properties of Steel Weld Metals 显示文摘 | Talas S | 2010 | Materials and Design2010，31，5： | 1 |
| 14 | Torsional behavior of reinforced high-strength concrete deep beams 显示文摘 | Samir A A Tamim A S Tala A | 1999 | ACI Structural Journal1999，96，6： | 1 |
| 15 | Montelukast for children with obstructive sleep apnea:a double-blind,placebo-controlled study显示文摘 | GOLDBART A D GREENBERG-DOTAN S TALA | 2012 | Pediatrics2012，130，： | 1 |
| 16 | Joining of microwave sintered Fe-26A1, Fe-3OAI, Fe-26AI-14Ti and Fe-3OAI-14Ti powder mixtures by diffusion bonding using Cu interlayer显示文摘 | Cakmakkaya M Talas S | 2012 | Journal of the Faculty of the Engineering and Architeeture of Gazi University2012，27，1： | 1 |
| 17 | Blunt and penetrating object injuries in housekeepers working in a Turkish University Hospital显示文摘 | Erdem Y Tala M S | 2006 | Am J Infect Control2006，34，4： | 1 |
| 18 | Numerical analysis of the fin spacing effect on the horseshoe vortex system evolution in a tworows finnedtube heat exchanger显示文摘 | SimoTala J V Russeil S Bougeard D | 2013 | International Journal of Numerical Methods for Heat and Fluid Flow2013，23，7： | 1 |
| 19 | Occupational exposure to blood and body fluids a-mong Turkish nuring students during clinical practice train-ing:frequency of needlestick/sharp injuries and hepatitis Bimmunization显示文摘 | Talas M S | 2009 | Journal of Clinical Nursing2009，18，10： | 1 |
| 20 | Designed catalysts for hydrodechlorination,reduction and reductive amination reactions显示文摘 | Margitfalvi J L Gobolos S Talas E | 1991 | Studies in Surface Science and Catalysis1991，63，： | 1 |
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