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20篇 您的检索式:作者名="Tam KS"
    题名 作者 年代 出处 被引量
1Mutations around interferon sensitivity-determining region:A pilot resistance report of hepatitis C virus 1b in a Hong Kong population显示文摘AIM: To explore mutations around the interferon sensitivity-determining region (ISDR) which are associated with the resistance of hepatitis C virus 1b (HCV-1b) to interferon-α treatment. METHODS: Thirty-seven HCV-1b samples were ob- tained from Hong Kong patients who had completed the combined interferon-α/ribavirin treatment for more than one year with available response data. Nineteen of them were sustained virological responders, while 18 were non-responders. The amino acid sequences of the extended ISDR (eISDR) covering 64 amino acids upstream and 67 amino acids downstream from the previously reported ISDR were analyzed. RESULTS: One amino acid variation (I2268V, P = 0.023) was significantly correlated with treatment outcomein this pilot study with a limited number of patients, while two amino acid variations (R2260H, P = 0.05 and S2278T, P = 0.05) were weakly associated with treatment outcome. The extent of amino acid variations within the ISDR or eISDR was not correlated with treatment outcome as previously reported. CONCLUSION: Three amino acid mutations near but outside of ISDR may associate with interferon treatment resistance of HCV-1b patients in Hong Kong.Xiao-Ming Zhou Paul KS Chan John S Tam 2011World Journal of Gastroenterology2011,17,48:3
2Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: implications for Th17-mediated inflammation in auto-immunity 显示文摘Wong CK Lit LC Tam KS 2008Clin Immunol2008,127,3:1
3A randomized controlled trial of low-dose recombinant human growth hormone in the treatment of malnourished elderly medical patients显示文摘Chu LW Lam ks Tam SC 2001Clin Endocrinol Metal2001,86,5:1
4Smoking and tuber eulosis among the elderly in Hong Kong显示文摘Leung CC Li T Lain TH Yew WW Law WS Tam CM Chan WM Chan CK Ho KS Chang KC 2004Am J Respir Crit Care Med2004,170,9:1
5Macular hole surgery with or without indocyanine green stained internal limit- hag membrane peeling 显示文摘Kwok AK Lai TY Yuen KS Tam BS Wong VW 2003Clin Experiment Ophthalmol2003,31,6:1
6Improved liquid chromatography- tandem mass spectrometry method in clinical utility for the diagnosis of Cushing's syndrome显示文摘Fong BM Tam S Leung KS 2010Anal Bioanal Chem2010,396,2:1
7The alarmin functions of high-mobility group box-1 and IL-33 in the pathogenesis of systemic lupus erythematosus显示文摘Yu SL Wong CK Tam KS 2013Expert Rev Clin Immunol2013,9,8:1
8Hypopituitarism after tuberculous meningitis in childhood显示文摘Lam KS Sham MM Tam SC 1993Ann Intern Med1993,118,9:1
9Delayed stimulatory effect of low-intensity shockwaves on human periosteal cells显示文摘Tam KF Cheung WH Lee KM Qin L Leung KS 0,,:1
10A linear matrix inequality approach for theeontrol of uncertain fuzzy systems显示文摘Leung F Tam Peter KS Lam H K 0,,:1
11Segmental intestinal transporters and metabolic enzymes on intestinal drug absorption 显示文摘Tam D Tirona RG Pang KS 2003Drug Metab Dispos2003,31,4:1
12Decreased ex vivo produxtion of TNF-alpha and IL-8 by peripheral blood ceils of patients with rheumatoid arthritis after infliximab therapy显示文摘Lun SW Wong CK Tam KS 2007Int Immunophannacol2007,7,13:1
13Fuzzy model-based controller for inverted pendulum 显示文摘WONG L K LEUNG F H F TAM P KS 1996Eelctron Letters1996,32,18:1
14Enhancing the utilization of photovoltaic power generation by superconductive magnetic energy storage 显示文摘Tam KS Kumar P and Foreman M 1989Energy Conversion IEEE Transactions on1989,4,3:1
15Closed -loop feedback computer -controlled infusion of phenylephrine for maintaining blood pressure during spinal anaesthesia for caesarean section: a preliminary descriptive study 显示文摘Ngan Kee WD Tam YH Khaw KS 2007Anaesthesia2007,62,12:1
16Elevated production of B cell chemo- kine CXCL13 is correlated with systemic lupus erythematosus disease activity显示文摘Wang CK Wong PT Tam KS 2010J Clin Immunol2010,30,1:1
17Total muscle-sparing uniportal video-assisted thoracoscopic surgery lobectomy显示文摘Tam JK Lira KS 2013Ann Thorac Surg2013,96,6:1
18Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization显示文摘By Michael D Gunn KS Tam C 1999J Exp Med1999,189,3:1
19Randomized controlled trial low- dose recombinant human growth hormone in the treatment of malnourished elderly medical patients显示文摘Chu LW Lam KS Tam SC 2001Clin Endocrin Meta2001,86,:1
20The development of haematopoietic cells is biased in embryonic stem cell chimaeras显示文摘Berger CN Tam PP Sturm KS 1995Dev Biol1995,170,2:1
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