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| 1 | Additive manufacturing of magnesium alloys显示文摘Magnesium alloys are a promising new class of degradable biomaterials that have a similar stiffness to bone,which minimizes the harmful effects of stress shielding.Use of biodegradable magnesium implants eliminates the need for a second surgery for repair or removal.There is a growing interest to capitalize on additive manufacturing's unique design capabilities to advance the frontiers of medicine.However,magnesium alloys are difficult to 3D print due to the high chemical reactivity that poses a combustion risk.Furthermore,the low vaporization temperature of magnesium and common biocompatible alloying elements further increases the difficulty to print fully dense structures that balance strength and corrosion requirements.The purpose of this study is to survey current techniques to 3D print magnesium constructs and provide guidance on best additive practices for these alloys. | Sam Ortgies Ali Tamayol Florin Bobaru Michael P.Sealy | 2020 | Bioactive Materials2020，5，1： | 4 |
| 2 | In vivo printing of growth factor-eluting adhesive scaffolds improves wound healing显示文摘Acute and chronic wounds affect millions of people around the world,imposing a growing financial burden on patients and hospitals.Despite the application of current wound management strategies,the physiological healing process is disrupted in many cases,resulting in impaired wound healing.Therefore,more efficient and easy-to-use treatment modalities are needed.In this study,we demonstrate the benefit of in vivo printed,growth factor-eluting adhesive scaffolds for the treatment of full-thickness wounds in a porcine model.A custom-made handheld printer is implemented to finely print gelatin-methacryloyl(GelMA)hydrogel containing vascular endothelial growth factor(VEGF)into the wounds.In vitro and in vivo results show that the in situ GelMA crosslinking induces a strong scaffold adhesion and enables printing on curved surfaces of wet tissues,without the need for any sutures.The scaffold is further shown to offer a sustained release of VEGF,enhancing the migration of endothelial cells in vitro.Histological analyses demonstrate that the administration of the VEGF-eluting GelMA scaffolds that remain adherent to the wound bed significantly improves the quality of healing in porcine wounds.The introduced in vivo printing strategy for wound healing applications is translational and convenient to use in any place,such as an operating room,and does not require expensive bioprinters or imaging modalities. | Kristo Nuutila Mohamadmahdi Samandari Yori Endo Yuteng Zhang Jacob Quint Tannin ASchmidt b Ali Tamayol Indranil Sinha | 2022 | Bioactive Materials2022，7，2： | 3 |
| 3 | Biofabrication of natural hydrogels for cardiac,neural,and bone Tissue engineering Applications显示文摘Natural hydrogels are one of the most promising biomaterials for tissue engineering applications,due to their biocompatibility,biodegradability,and extracellular matrix mimicking ability.To surpass the limitations of conventional fabrication techniques and to recapitulate the complex architecture of native tissue structure,natural hydrogels are being constructed using novel biofabrication strategies,such as textile techniques and three-dimensional bioprinting.These innovative techniques play an enormous role in the development of advanced scaffolds for various tissue engineering applications.The progress,advantages,and shortcomings of the emerging biofabrication techniques are highlighted in this review.Additionally,the novel applications of biofabricated natural hydrogels in cardiac,neural,and bone tissue engineering are discussed as well. | Kamil Elkhoury Margaretha Morsink Laura Sanchez-Gonzalez Cyril Kahn Ali Tamayol Elmira Arab-Tehrany | 2021 | Bioactive Materials2021，6，11： | 2 |
| 4 | Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels显示文摘 | Kan Yue Grissel Trujillo-de Santiago Mario Moisés Alvarez Ali Tamayol Nasim Annabi Ali Khademhosseini | 2015 | Biomaterials2015，，： | 1 |
| 5 | Water permeation through gas diffusion layers of proton exchange membrane fuel cells 显示文摘 | Tamayol A Bahrami M | 2011 | Journal of Power Sources2011，196，15： | 1 |
| 6 | Thermal Assessment of Forced Convection Through Metal Foam Heat Exchangers 显示文摘 | Tamayol A Hooman K | 2011 | Journal of Heat Transfer2011，133，11： | 1 |
| 7 | Effects of inlet position and baffle configuration on hydraulic performance of primary settling tanks显示文摘 | Tamayol A Firoozabadi B Ahmadi G | 2008 | Journal of Hydraulic Engineering2008，134，7： | 1 |
| 8 | Giant pigmented nevi: clinical,histopathologic, and therapeutic considerat ions显示文摘 | Ruiz-Maldonador Tamayol Laterzaam | 1992 | J Pediatr1992，120，6： | 1 |
| 9 | Effects of Inlet Position and Baffle Configuration on Hydraulic Performance of Primary Settling Tanks 显示文摘 | Tamayol A Firoozabadi B Ahmadi G | 2008 | Journal of Hydraulic Engineering (S0733-9429)2008，134，7： | 1 |
| 10 | In-plane gas permeability of proton exchange membrane fuel cell gas diffusion layers 显示文摘 | TAMAYOL A BAHRAMI M | 2011 | Journal of Power Sources2011，196，： | 1 |
| 11 | Low Reynolds number flows across ordered arrays of micro-cylinders embedded in a rectangular micro/mini channel 显示文摘 | TAMAYOL A YEOM J JUNG S Y | 2013 | International Journal of Heat and Mass Transfer2013，58，12： | 1 |
| 12 | Functionalized liposomes for targeted breast cancer drug delivery显示文摘Despite the exceptional progress in breast cancer pathogenesis,prognosis,diagnosis,and treatment strategies,it remains a prominent cause of female mortality worldwide.Additionally,although chemotherapies are effective,they are associated with critical limitations,most notably their lack of specificity resulting in systemic toxicity and the eventual development of multi-drug resistance(MDR)cancer cells.Liposomes have proven to be an invaluable drug delivery system but of the multitudes of liposomal systems developed every year only a few have been approved for clinical use,none of which employ active targeting.In this review,we summarize the most recent strategies in development for actively targeted liposomal drug delivery systems for surface,transmembrane and internal cell receptors,enzymes,direct cell targeting and dual-targeting of breast cancer and breast cancer-associated cells,e.g.,cancer stem cells,cells associated with the tumor microenvironment,etc. | Janske Nel Kamil Elkhoury Émilie Velot Arnaud Bianchi Samir Acherar Grégory Francius Ali Tamayol Stéphanie Grandemange Elmira Arab-Tehrany | 2023 | Bioactive Materials2023，，6： | 0 |
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