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| 1 | Contemporary approach to diagnosis and classification of renal cell carcinoma with mixed histologic features显示文摘Renal cell carcinoma (RCC) is an important contributor to cancer-specific mortality worldwide. Targeted agents that inhibit key subtype-specific signaling pathways have improved survival times and have recently become part of the standard of care for this disease. Accurately diagnosing and classifying RCC on the basis of tumor histology is thus critical. RCC has been traditionally divided into clear-cell and non-clearcell categories, with papillary RCC forming the most common subtype of non-clear-cell RCC. Renal neoplasms with overlapping histologies, such as tumors with mixed clear-cell and papillary features and hybrid renal oncocytic tumors, are increasingly seen in contemporary practice and present a diagnostic challenge with important therapeutic implications. In this review, we discuss the histologic, immunohistochemical, cytogenetic, and clinicopathologic aspects of these differential diagnoses and illustrate how the classification of RCC has evolved to integrate both the tumor's microscopic appearance and its molecular fingerprint. | Kanishka Sircar Priya Rao Eric Jonasch Federico A. Monzon Pheroze Tamboli | 2013 | Chinese Journal of Cancer2013，32，6： | 4 |
| 2 | Collision tumor of the kidney composed of clear cell carcinoma and collecting duct carcinoma: report of a case with unusual morphology and clinical follow-up显示文摘We report the case of a 67-year-old female who presented with a large renal mass. Gross examination of the nephrectomy specimen demonstrated a 6-cm renal mass that invaded into the renal sinus and perinephric fat. Histologic examination revealed two distinct tumor types. The first type was a conventional(clear cell) renal cell carcinoma that was of low nuclear grade and comprised the minority of the overall tumor. The second type was a high-grade collecting duct carcinoma with glandular/tubular differentiation and composed the majority of the tumor. Immunohistochemical studies demonstrated distinctive patterns of the two tumor types, thus confirming two distinct lineages. Five months postoperatively, the patient developed metastasis to the lungs and right hilar lymph node region. A fine needle aspiration of a lung nodule demonstrated a metastatic, poorly differentiated carcinoma, similar to the collecting duct carcinoma component in the kidney. Collision tumors of the kidney are rare with fewer than 10 cases reported in the literature. Our report further expands the spectrum of this rare phenomenon. | Rhonda Burch-Smith Nizar M Tannir Erika Resetkova Pheroze Tamboli Priya Rao | 2014 | Chinese Journal of Cancer2014，33，7： | 3 |
| 3 | Prognostic Impact of Histologic Subtyping of Adult Renal Epithelial Neoplasms: An Experience of 405 Cases显示文摘 | Mahul B. Amin Mitual B. Amin Pheroze Tamboli Javid Javidan Hans Stricker Mariza De-Peralta Venturina Anita Deshpande Mani Menon | 2002 | The American Journal of Surgical Pathology2002，，： | 2 |
| 4 | Genetic variations in mi croRNA-related genes are associated with survival and recur- rence in patients with renal cell carcinoma显示文摘 | Lin J Horikawa Y Tamboli P | 2010 | Carcinogenesis2010，31，10： | 1 |
| 5 | Gene and protein expression markers of response tocombined antiangiogenic and epidermal growth factortargeted therapy in renal cell carcinoma显示文摘 | TsavachidouFenner D Tannir N Tamboli P | 2010 | Ann On-coU2010，21，8： | 1 |
| 6 | Oncocytic renal neoplasmsdiagonostic considerations显示文摘 | ABRAHAMS NA TAMBOLI P | 2005 | Clin Lab Med2005，25，2： | 1 |
| 7 | Prognostic impact of histologic subtyping of adult renal epithelial neoplasms: an experience of 405 cases显示文摘 | Amin MB Tamboli P Javidan J | 2002 | Am J Surg Pathol2002，26，3： | 1 |
| 8 | Micropapillary component in lung adenocarcinoma:a distinct histologic variant with biologic significance显示文摘 | Amin MB Tamboli P Merchant SH | 2000 | Am J Surg Pathol2000，26，3： | 1 |
| 9 | The importance of caloric re-striction in the early improvements in insulin sensitivity after Roux-en-Y gastric bypass surgery显示文摘 | Isbell JM Tamboli RA Hansen EN | 2010 | Diabetes Care2010，33，7： | 1 |
| 10 | Oncological efficacy and safety of nephron- sparing surgery for selected patients with locally ad- vanced renal cell carcinoma显示文摘 | Margulis V Tamboli P Jaeobsohn K M Swanson D A Wood C G | 2007 | BJU Int2007，100，： | 1 |
| 11 | Electrochemical characterization of copper chemical mechanical polishing显示文摘 | DU T TAMBOLI D DESAI V | 2003 | Microelectronic Engineering2003，69，： | 1 |
| 12 | Synthesis and anticancer activity of heteroaromatic linked 4~ -amido podophyllotoxins as apoptotic inducing agents显示文摘 | Kamal A Tamboli J R Vishnuvardhan M V | 2013 | Bioorg Med Chem Lett2013，23，1： | 1 |
| 13 | Fecal calprotectin in Crohn's disease:new family ties显示文摘 | Richard F Colombel JF | 2003 | Gastroenterology2003，124，7： | 1 |
| 14 | Clinical relevance of advances in genetics and pharmacogenetics of IBD显示文摘 | Ahmad T Tamboli CP Jewell D | 2004 | Gastroenterology2004，126，： | 1 |
| 15 | Recent patents and emerging therepeutics in the treatment of allergic conjunctivitis显示文摘 | Gyan P Mishra Viral Tamboli | 2011 | Recent Pat Inflamm Allergy Drug Discov2011，5，1： | 1 |
| 16 | Prognostic impact of histologic subtyping of adult renal epithelial neoplasms:an experience of 405 cases显示文摘 | Amin MB Tamboli P Javidan J | 2002 | Am J Surg Pathol2002，26，： | 1 |
| 17 | Mucinous tubular and spindle cell carcinoma of kidney is probably a variant of papillary renal cell carcinoma with spindle cell features显示文摘 | Shen SS Ro JY Tamboli P | 2007 | Ann Diagn Pathol2007，11，1： | 1 |
| 18 | Degradation of Orange 3R, mixture of dyes and textile effluent and production of polyhydroxyalkanoates from biomass obtained after degradation显示文摘 | Tamboli DP Gomare SS Kalme SS | 2010 | International Biodeterioration & Biodegradation2010，64，8： | 1 |
| 19 | Renal cell carcinoma clinically involving adjacent organs:experience with aggressive surgical management显示文摘 | Margulis V Sanchez-Ortiz RF Tamboli P | 2007 | Cancer2007，109，： | 1 |
| 20 | Carcinoma of lung with rhabdoid features 显示文摘 | Tamboli P Toprani TH Amin MB | 2004 | Hum Pathol2004，35，1： | 1 |
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