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| 1 | Evaluation of the ability of arsenic species to traverse cell membranes by simple diffusion using octanol-water and liposome-water partition coefficients显示文摘在生活有机体的砷新陈代谢依赖于不同的砷种类的能力穿越生物的膜。简单散开提供其他的流入和流出线路给能在房间增加为新陈代谢可得到的砷的数量的调停的运输机制。使用 octanol 水和 liposome 水分区系数,砷的酸的能力,砷酸盐, methylarsonate, dimethylarsinate, thio-methylarsonate, thio-dimethylarsinic 酸, arsenotriglutathione 和通过房间膜的类脂化合物 bilayer 扩散的 monomethylarsonic diglutathione 被调查。砷种类的分子的建模被用来解释结果。有砷酸盐, methylarsonate 和 thio-methylarsonate 的异常的所有砷种类能通过 liposomes 的类脂化合物 bilayer 扩散,与在 0.04 和 0.13 之间的 liposome 水分区系数。三价的砷种类和 thio 五价的砷种类显示出更高的分区系数,建议他们能容易穿越由被动简单散开的房间膜。与含氧五价的砷种类相比给这些的更高的毒性种类,这研究提供支持与人的暴露联系到的风险的证据三价并且 thio 砷种类。 | Teresa Chavez-Capilla William Maher Tamsin Kelly Simon Foster | 2016 | Journal of Environmental Sciences2016，28，11： | 4 |
| 2 | Estimating the prevalence of Echinococcus in domestic dogs in highly endemic for echinococcosis显示文摘Background:Cystic echinococcosis(CE)and alveolar echinococcosis(AE)are highly endemic in Xiji County of Ningxia Hui Autonomous Region(NHAR)in China where the control campaign based on dog de-worming with praziquantel has been undertaken over preceding decades.This study is to determine the current prevalence of Echinococcus granulosus and E.multilocularis in domestic dogs and monitor the echinococcosis transmission dynamics.Methods:Study villages were selected using landscape patterns(Geographic Information System,GIS)for Echinococcus transmission“hot spots”,combined with hospital records identifying risk areas for AE and CE.A survey of 750 domestic dogs,including copro-sampling and owner questionnaires,from 25 selected villages,was undertaken in 2012.A copro-multiplex PCR assay was used for the specific diagnosis of E.granulosus and E.multilocularis in the dogs.Data analysis,using IBM SPSS Statistics,was undertaken,to compare the prevalence of the two Echinococcus spp.in dogs between four geographical areas of Xiji by theχ^(2)test.Univariate analysis of the combinations of outcomes from the questionnaire and copro-PCR assay data was carried out to determine the significant risk factors for dog infection.Results:The highest de-worming rate of 84.0%was found in the northwest area of Xiji County,and significant differences(P<0.05)in the de-worming rates among dogs from the four geographical areas of Xiji were detected.The highest prevalence(19.7%,59/300)of E.multilocularis occurred in northwest Xiji,though the highest prevalence(18.1%,38/210)of E.granulosus occurred in southwest Xiji.There was no significant difference(P>0.05)in the prevalence of E.granulosus in dogs from the northwest,southwest,northeast,and southeast of Xiji,but there were significant differences(P<0.05)between dogs infected with E.multilocularis from the four areas.None of the other independent variables was statistically significant.Conclusions:The results from this study indicate a high prevalence of both E.granulosus and E.muiltilocularis in dogs in Xiji County,NHAR.Transmission of E.multilocularis was more impacted by geographical risk-factors in Xiji County than that of E.granulosus.Dogs have the potential to maintain the transmission of both species of Echinococcus within local Xiji communities,and the current praziquantel dosing of dogs appears to be ineffective or poorly implemented in this area. | Cong-Nuan Liu Yang-Yang Xu Angela M.Cadavid-Restrepo Zhong-Zi Lou Hong-Bin Yan Li Li Bao-Quan Fu Darren J.Gray Archie A.Clements Tamsin S.Barnes Gail M.Williams Wan-Zhong Jia Donald P.McManus Yu-Rong Yang | 2018 | Infectious Diseases of Poverty2018，7，1： | 3 |
| 3 | The landscape epidemiology of echinococcoses显示文摘Echinococcoses are parasitic diseases of major public health importance globally.Human infection results in chronic disease with poor prognosis and serious medical,social and economic consequences for vulnerable populations.According to recent estimates,the geographical distribution of Echinococcus spp.infections is expanding and becoming an emerging and re-emerging problem in several regions of the world.Echinococcosis endemicity is geographically heterogeneous and over time it may be affected by global environmental change.Therefore,landscape epidemiology offers a unique opportunity to quantify and predict the ecological risk of infection at multiple spatial and temporal scales.Here,we review the most relevant environmental sources of spatial variation in human echinococcosis risk,and describe the potential applications of landscape epidemiological studies to characterise the current patterns of parasite transmission across natural and human-altered landscapes.We advocate future work promoting the use of this approach as a support tool for decision-making that facilitates the design,implementation and monitoring of spatially targeted interventions to reduce the burden of human echinococcoses in disease-endemic areas. | Angela M.Cadavid Restrepo Yu Rong Yang Donald P.McManus Darren J.Gray Patrick Giraudoux Tamsin S.Barnes Gail M.Williams Ricardo J.Soares Magalhães Nicholas A.S.Hamm Archie C.A.Clements | 2016 | Infectious Diseases of Poverty2016，5，1： | 2 |
| 4 | The British Child and Adolescent Mental Health Survey 1999: The Prevalence of DSM-IV Disorders显示文摘 | Tamsin Ford Robert Goodman Howard Meltzer | 2003 | J Am Acad Child Adolesc Psychiatry2003，42，10： | 1 |
| 5 | The current role of the artificial urinary sphincter for the treatment of urinary incontinence显示文摘 | Mahreen H Tamsin J G Suzine N V | 2005 | J Urol2005，174，： | 1 |
| 6 | Engineering a peptide epitope display system on filamentous bacteriophage显示文摘 | Richard N. Perham Tamsin D. Terry Anne E. Willis Judith Greenwood Fulvia di Marzo Veronese Ettore Appella | 1995 | FEMS Microbiology Reviews1995，，1： | 1 |
| 7 | The British Child and Adolescent Mental Health Survey 1999: The Prevalence of DSM-IV Disorders 显示文摘 | Ford Tamsin Goodman Robert Meltzer H | 2003 | J Am Acad Child Adolesct Psychiatry2003，42，10： | 1 |
| 8 | Predictive Value of Callous-Unemotional Traits in a Large Community Sample显示文摘 | Paul Moran Richard Rowe Clare Flach Jacqueline Briskman Tamsin Ford Barbara Maughan Stephen Scott Robert Goodman | 2009 | Journal of the American Academy of Child & Adolescent Psychiatry2009，，11： | 1 |
| 9 | The british child and adolescent mental health survey 1999:the prevalence of DSM-Ⅳ disorders显示文摘 | Tamsin F Robert G Howard M | 2003 | J Am Acad Child Adolesc Psychiatry2003，42，10： | 1 |
| 10 | Plasmid-Encoded tetB tetracycline resistance in Haemophilus parasuis 显示文摘 | John F L Tamsin D T Blackall P J | 2005 | Antimicrobial Agentsand Chemotherapy2005，49，： | 1 |
| 11 | Diatom Assessment of Past Environmental Changes in Lakes Located Near the Noril’sk (Siberia) Smelters显示文摘 | Neal Michelutti Tamsin E. Laing John P. Smol | 2001 | Water Air and Soil Pollution2001，，1： | 1 |
| 12 | Weighing up the Influence of Context on Judgements of Mathematical Literacy 显示文摘 | Tamsin Meaney | 2007 | International Journal of Science and Mathematics Education2007，，5： | 1 |
| 13 | Sleep disruption experienced by surgical pa- tients in an acute hospital 显示文摘 | Lane Tamsin | 2008 | British journal of nursing ( Mark Allen Publishing)2008，17，12： | 1 |
| 14 | Plasmid-encoded tet B tetracycline resistance in Haemophilus parasuis 显示文摘 | JOHN F L TAMSIN D T BLACKALL P J | 2005 | An tirnicrob Agents Chemother2005，49，5： | 1 |
| 15 | Diatom Inferred Acidity History Of 32 Lakes On The Kola Peninsula, Russia显示文摘 | Jan Weckstr?m Jeffrey A. Snyder Atte Korhola Tamsin E. Laing Glen M. Macdonald | 2003 | Water Air and Soil Pollution (-)2003，，1： | 1 |
| 16 | The role of nuclear factor kappa B inhuman labour显示文摘 | Tamsin ML Phillip RB | 2005 | Reproduction2005，130，： | 1 |
| 17 | Localization of urea transporter B in the developing bovine rumen显示文摘Urea nitrogen secreted from blood to rumen is a crucial factor shaping the symbiotic relationship between host ruminants and their microbial populations.Passage of urea across rumen epithelia is facilitated by urea transporter B(UT-B),but the long-term regulation of these proteins remains unclear.As ruminal function develops over a period of months,the developing rumen is an excellent model with which to investigate this regulation.Using rumen epithelium samples of calves from birth to 96 d of age,this study performed immunolocalization studies to localize and semi-quantify UT-B protein development.As expected,preliminary experiments confirmed that ruminal monocarboxylate transporter 1(MCT1)short chain fatty acid transporter protein abundance increased with age(P<0.01,n=4).Further investigation revealed that ruminal UT-B was present in the first few weeks of life and initially detected in the basolateral membrane of stratum basale cells.Over the next 2 months,UT-B staining spread to other epithelial layers and semi-quantification indicated that UT-B abundance significantly increased with age(P<0.01,n=4 or 6).These changes were in line with the development of rumen function after the advent of solid feed intake and weaning,exhibiting a similar pattern to both MCT1 transporters and papillae growth.This study therefore confirmed age-dependent changes of in situ ruminal UT-B protein,adding to our understanding of the long-term regulation of ruminal urea transporters. | Chongliang Zhong Tamsin Lyons Orla Heussaff Evelyn Doyle Eoin O'Hara Sinead M.Waters David Kenny Gavin S.Stewart | 2022 | Animal Nutrition2022，，3： | 1 |
| 18 | Children who run away from home : Risks for suicidal behavior and substance misuse 显示文摘 | HOWARD M TAMSIN F PAUL B | 2012 | J Adoles Health2012，，51： | 1 |
| 19 | THE CURRENT ROLE OF THE ARTIFICIAL URINARY SPHINCTER FOR THE TREATMENT OF URINARY INCONTINENCE显示文摘 | MAHREEN HUSSAIN TAMSIN J. GREENWELL SUZIE N. VENN ANTHONY R. MUNDY | 2005 | The Journal of Urology2005，，2： | 1 |
| 20 | The true self online: Personality correlates of preference for self-expression online, and observer ratings of personality online and offline显示文摘 | Tamsin C. Marriott Tom Buchanan | 2014 | Computers in Human Behavior2014，，： | 1 |
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