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12篇 您的检索式:作者名="Tang EJ"
    题名 作者 年代 出处 被引量
1Surveying brain tumor heterogeneity by single-cell RNA-sequencing of multi-sector biopsies显示文摘Brain tumors are among the most challenging human tumors for which the mechanisms driving progression and heterogeneity remain poorly understood.We combined single-cell RNA-seq with multi-sector biopsies to sample and analyze single-cell expression profiles of gliomas from 13 Chinese patients.After classifying individual cells;we generated a spatial and temporal landscape of glioma that revealed the patterns of invasion between the different sub-regions of gliomas.We also used single-cell inferred copy number variations and pseudotime trajectories to inform on the crucial branches that dominate tumor progression.The dynamic cell components of the multi-region biopsy analysis allowed us to spatially deconvolute with unprecedented accuracy the transcriptomic features of the core and those of the periphery of glioma at single-cell level.Through this rich and geographically detailed dataset,we were also able to characterize and construct the chemokine and chemokine receptor interactions that exist among different tumor and non-tumor cells.This study provides the first spatial-level analysis of the cellular states that characterize human gliomas.It also presents an initial molecular map of the cross-talks between glioma cells and the surrounding microenvironment with single-cell resolution.Kai Yu Yuqiong Hu Fan Wu Qiufang Guo Zenghui Qian Waner Hu Jing Chen Kuanyu Wang Xiaoying Fan Xinglong Wu John EJ Rasko Xiaolong Fan Antonio lavarone Tao Jiang Fuchou Tang Xiao-Dong Su 2020National Science Review2020,7,8:4
2European Polymer Journal显示文摘Tang EJ Liu H Sun LM 2007(10):4 210-4 2182007,,10:1
3Colliod and Polymer Science显示文摘Tang EJ Cheng GX Pang XS 2006284 (4) :422-4282006,284,4:1
4Dexmedetomidine controls agita- tion and facilitates reliable,serial neurological examinations in a non-intubated patient with traumatic brain injury 显示文摘Tang JF Chen PL Tang EJ 2011Neurocrit Care2011,15,1:1
5Dexmedetomidine con-trols agitation and facilitates reliable,serial neurological examinations in a non-intubate patient with trumatic brain injury显示文摘Tang JF Chen PL Tang EJ 0,,1:1
6dexmedetomidine medetomidine cintrols agitation and facilitates reliable,serial neurological examinations in a non-intubated patient with traumatic brain injury显示文摘Tang JF Chen PL Tang EJ 2011Neurocrit Care2011,15,1:1
7Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations 显示文摘Tang K Ngoi SM Gwee PC Chua JM Lee EJ Chong SS 2002Pharmacogenetics2002,12,6:1
8Genes -environment interactions in obesity - and diabetes - associated pancreatic cancer: a GWAS data analysis 显示文摘TANG H WEI P DUELL EJ 2014Cancer Epidemiol Biomarkers Prev2014,23,1:1
9Dexmedetomidine controls agitation and facilitates reliable,serial neurological examinations in a non-intubated patient with traumatic brain injury显示文摘Tang JF Chen PL Tang EJ 0,,01:1
10Dexmedetomidine controls agitation and facilitates reliable,serial neurological examinations in a non-intubated patient with traumatic brain injury显示文摘Tang JF Chen PL Tang EJ 2011Neurocrit Care2011,15,1:1
11Colliod and Polymer Science显示文摘Tang EJ Cheng GX Pang XS 2006284(4):422-4282006,284,4:1
12Dexmedetomidine Controls Agitation and Facilitates Reliable,Serial Neurological Examinations in a Non-Intubated Patient with Traumatic Brain Injury显示文摘Tang JF Chen PL Tang EJ 2011Neurocritical Care2011,15,1:1
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