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| 1 | North Qinling Paleozoic granite associations and their variation in space and time: Implications for orogenic processes in the orogens of central China显示文摘Integrated zircon U-Pb dating and whole rock geochemical analyses have been carried out for two typical S-and I-type granitoids in the north Qinling. Zircon dating by SIMS of the Piaochi S-type grani- toids yields an emplacement age of 495±6 Ma. The granitoids show whole-rock εNd(t)=-8.2--8.8, zircon εHf(t)=-6―-39. The Huichizi I-type granitoids have emplacement ages of 421±27 Ma and 434±7 Ma es- tablished by LA-ICP-MS and SIMS methods, respectively. Their whole-rock εNd(t)=-0.9-0.9 and zircon εHf(t)=-11-8.4. Combined with statistical analyses of 28 zircon ages of granitoid plutons collected from the literature, Paleozoic magmatism in the north Qinling can be divided into three stages. The first-stage magmatism (~505-470 Ma) mainly occurred in the east part of the north Qinling and has features of an I-type arc, associated with which are S-type granitoids such as Piaochi pluton. The early granitoids (~505-490 Ma) have close spatio-temporal relations to ultra-high-pressure (UHP) rocks, and thus are interpreted as an oceanic subduction system along a continental margin. The second-stage magmatism (~450-422 Ma) occured through the whole north Qinling, and is characterized by I-type granitoids represented by the Huichizi pluton. The magma is interpreted as partial melting of lower crust mixed by mantle-derived magma in a collisional setting with the uplift of terranes. The third-stage magmatism (~415-400 Ma) is dominated by I-type granitoids and only took place in the middle part of the north Qinling, and is regarded as a late-stage collision. The spatial and temporal variations of the Qinling Paleozoic magmatism reveal protracted subduction/collision. The subduction was initiated from the east part of the north Qinling, earlier than that in the Qilian-northern Qaidam, Kunlun, and northern Dabie regions. This demonstrates variations in time of subduction, accretion and collision of separate blocks or terranes in the orogenic systems in central China. | WANG Tao WANG XiaoXia TIAN Wei ZHANG ChengLi LI WuPing LI Shan | 2009 | Science China Earth Sciences2009，52，9： | 79 |
| 2 | Effects of different resuscitation fluid on severe acute pancreatitis显示文摘AIM: To compare effects of different resuscitation fluid on microcirculation, inflammation, intestinal barrier and clinical results in severe acute pancreatitis (SAP). METHODS: One hundred and twenty patients with SAP were enrolled at the Pancreatic Disease Institute between January 2007 and March 2010. The patients were randomly treated with normal saline (NS group), combination of normal saline and hydroxyethyl starch (HES) (SH group), combination of normal saline, hydroxyethyl starch and glutamine (SHG group) in resuscitation. The ratio of normal saline to HES in the SH and SHG groups was 3:1. The glutamine (20% glutamine dipeptide, 100 mL/d) was supplemented into the resuscitation liquid in the SHG group. Complications and outcomes including respiratory and abdominal infection, sepsis, abdominal hemorrhage, intra-abdominal hypertension, abdominal compartment syndrome (ACS), renal failure, acute respiratory distress syndrome (ARDS), multiple organ dysfunction syndrome (MODS), operation intervention, length of intensive care unit stay, length of hospital stay, and mortality at 60 d were compared. Moreover, blood oxygen saturation (SpO 2 ), gastric intramucosal pH value (pHi), intra-abdominal pressure (IAP), inflammation cytokines, urine lactulose/mannitol (L/M) ratio, and serum endotoxin were investigated to evaluate the inflammatory reaction and gut barrier. RESULTS: Compared to the NS group, patients in the SH and SHG groups accessed the endpoint more quickly (3.9 ± 0.23 d and 4.1 ± 0.21 d vs 5.8 ± 0.25 d, P < 0.05) with less fluid volume (67.26 ± 28.53 mL/kg/d, 61.79 ± 27.61 mL/kg per day vs 85.23 ± 21.27 mL/kg per day, P < 0.05). Compared to the NS group, incidence of renal dysfunction, ARDS, MODS and ACS in the SH and SHG groups was obviously lower. Furthermore, incidence of respiratory and abdominal infection was significantly decreased in the SH and SHG groups, while no significant difference in sepsis was seen. Moreover, less operation time was needed in the SH and SHG group than the NS group, but the difference was not significant. The mortality did not differ significantly among these groups. Blood SpO 2 and gastric mucosal pHi in the SH and SHG groups increased more quickly than in the NS group, while IAP was significantly decreased in the SH and SHG group. Moreover, the serum tumor necrosis factor-α, interleukin-8 and C-reactive protein levels in the SH and SHG groups were obviously lower than in the NS group at each time point. Furthermore, urine L/M ratio and serum endotoxin were significantly lower in the SH group and further decreased in the SHG group.CONCLUSION: Results indicated that combination of normal saline, HES and glutamine are more efficient in resuscitation of SAP by relieving inflammation and sustaining the intestinal barrier. | Gang Zhao Jun-Gang Zhang He-Shui Wu Jin Tao Qi Qin Shi-Chang Deng Yang Liu Lin Liu Bo Wang Kui Tian Xiang Li Shuai Zhu Chun-You Wang | 2013 | World Journal of Gastroenterology2013，19，13： | 56 |
| 3 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 4 | Contrasting trends of PM2.5 and surface-ozone concentrations in China from 2013 to 2017显示文摘Although much attention has been paid to investigating and controlling air pollution in China,the trends of air-pollutant concentrations on a national scale have remained unclear.Here,we quantitatively investigated the variation of air pollutants in China using long-term comprehensive data sets from 2013 to 2017,during which Chinese government made major efforts to reduce anthropogenic emission in polluted regions.Our results show a significant decreasing trend in the PM2.5 concentration in heavily polluted regions of eastern China,with an annual decrease of〜7%compared with measurements in 2013.The measured decreased concentrations of SO2>NO2 and CO(a proxy for anthropogenic volatile organic compounds)could explain a large fraction of the decreased PM2.5 concentrations in different regions.As a consequence;the heavily polluted days decreased significantly in corresponding regions.Concentrations of organic aerosol;nitrate;sulfate,ammonium and chloride measured in urban Beijing revealed a remarkable reduction from 2013 to 2017;connecting the decreases in aerosol precursors with corresponding chemical components closely.However;surface-ozone concentrations showed increasing trends in most urban stations from 2013 to 2017;which indicates stronger photochemical pollution.The boundary-layer height in capital c让ies of eastern China showed no significant trends over the Beijing-Tianjin-Hebei,Yangtze River Delta and Pearl River Delta regions from 2013 to 2017;which confirmed the reduction in anthropogenic emissions.Our results demonstrated that the Chinese government was successful in the reduction of particulate matter in urban areas from 2013 to 2017,although the ozone concentration has increased significantly;suggesting a more complex mechanism of improving Chinese air quality in the future. | Yonghong Wang Wenkang Gao Shuai Wang Tao Song Zhengyu Gong Dongsheng Ji Lili Wang Zirui Liu Guiqian Tang Yanfeng Huo Shili Tian Jiayun Li Mingge Li Yuan Yang Biwu Chu Tuukka Petaja Veli-Matti Kerminen Hong He Jiming Hao Markku Kulmala Yuesi Wang Yuanhang Zhang | 2020 | National Science Review2020，7，8： | 51 |
| 5 | Utility of squamous cell carcinoma antigen, carcinoembryonic antigen, Cyfra 21-1 and neuron specific enolase in lung cancer diagnosis: a prospective study from China显示文摘背景早察觉和诊断为为肺 cancer.However 的有效治疗策略的缘故是迫切的,一方便,节俭、相对精确的方法不是这里的 available.We 报导未来的研究在 lung.Methods 与可疑小瘤在病人之中在肺癌症的早诊断发现四个流行肿瘤标记的联合使用的可能的价值有在肺的可疑小瘤的 660 | SONG Wei-an LIU Xi TIAN Xiao-dong WANG Wei LIANG Chao-yang ZHANG Tao GUO Jun-tang PENG Yang-hong ZHOU Nai-kang | 2011 | Chinese Medical Journal2011，，20： | 38 |
| 6 | Crustal velocity structure in the Emeishan large igneous province and evidence of the Permian mantle plume activity显示文摘The Emeishan large igneous province(ELIP) in SW China is interpreted to be associated with an ancient mantle plume. Most of the constraints on the role of mantle plume in the generation of the Emeishan flood basalts were provided by geological and geochemical methods, but the geophysical investigation is very limited. In order to better understand the deep structure and features of ELIP, we have studied the crustal velocity structure using the data acquired from the Lijiang-Panzhihua-Qingzhen wide-angle seismic profile. This profile crosses the three sub-zones of the ELIP(the inner, intermediate, and outer zones), divided based on the differential erosion and uplift of the Maokou limestone. The results provided by the active source seismic experiment demonstrate:(1) The average depth of the crystalline basement along the profile is about 2 km.(2) The middle crust in the Inner Zone is characterized by high-velocity anomalies, with the average velocity of 6.2-6.6 km/s, which is about 0.1– 0.2 km/s higher than the normal one. The velocity of the lower crust in the inner zone is 6.9-7.2 km/s, higher than those observed in the intermediate and outer zones(6.7-7.0 km/s). Relatively low velocity anomalies appear in the upper, middle and lower crusts near the junction of the inner zone and intermediate zone, probably due to the effect of the Xiaojiang fault(XJF).(3) The average velocity of the crust is comparatively low on both sides of XJF, especially on the east side, and the average velocity of the consolidated continental crust is also low there. This may suggest that the XJF extends at least down to 40 km deep, even beyond through the crust.(4) The depth to the Moho discontinuity decrease gradually from 47-53 km in the inner zone, via 42-50 km in the intermediate zone to 38-42 km in the outer zone. In the inner zone, the Moho uplifts locally and the(consolidated) crust is characterized by high-velocity anomalies, which are likely related to intensive magma intrusion and underplating associated with melting of plume head. Overall the crustal velocity structure in the study area recorded the imprint left by the Permian Emeishan mantle plume. | XU Tao ZHANG ZhongJie LIU BaoFeng CHEN Yun ZHANG MingHui TIAN XiaoBo XU YiGang TENG JiWen | 2015 | Science China Earth Sciences2015，58，7： | 36 |
| 7 | Phosphate-Solubilizing and -Mineralizing Abilities of Bacteria Isolated from Soils显示文摘Microorganisms capable of solubilizing and mineralizing phosphorus (P) pools in soils are considered vital in promoting P bioavailability. The study was conducted to screen and isolate inorganic P-solubilizing bacteria (IPSB) and organic P-mineralizing bacteria (OPMB) in soils taken from subtropical flooded and temperate non-flooded soils, and to compare inorganic P-solubilizing and organic P-solubilizing abilities between IPSB and OPMB. Ten OPMB strains were isolated and identified as Bacillus cereus and Bacillus megaterium, and five IPSB strains as B. megaterium, Burkholderia caryophylli, Pseudomonas cichorii, and Pseudomonas syringae. P-solubilizing and -mineralizing abilities of the strains were measured using the methods taking cellular P into account. The IPSB strains exhibited inorganic P-solubilizing abilities ranging between 25.4-41.7 μg P mL-1 and organic P-mineralizing abilities between 8.2-17.8 μg P mL-1. Each of the OPMB strains also exhibited both solubilizing and mineralizing abilities varying from 4.4 to 26.5 μg P mL-1 and from 13.8 to 62.8 μg P mL-1, respectively. For both IPSB and OPMB strains, most of the P mineralized from the organic P source was incorporated into the bacterial cells as cellular P. A significantly negative linear correlation (P < 0.05) was found between culture pH and P solubilized from inorganic P by OPMB strains. The results suggested that P solubilization and mineralization could coexist in the same bacterial strain. | TAO Guang-Can TIAN Shu-Jun CAI Miao-Ying XIE Guang-Hui | 2008 | Pedosphere2008，18，4： | 33 |
| 8 | The critical roles of mitophagy in cerebral ischemia显示文摘 | Yan-Cheng Tang Hong-Xia Tian Tao Yi Hu-Biao Chen | 2016 | Protein & Cell2016，7，10： | 28 |
| 9 | Different histological subtypes of parotid gland tumors: CT findings and diagnostic strategy显示文摘AIM:To present computed tomography(CT) findings of different histological subtypes of parotid gland masses in detail and to establish diagnostic strategy.METHODS:From January 2009 to November 2011,56 patients were collected through the histopathology and Picture Archiving and Communication Systems records,which revealed 5 basal cell adenoma(BCA),16 pleomorphic adenoma(PA),25 Warthin's tumor(War-T),3 Kimura's disease(KD) and 7 parotid carcinoma(PCa) cases.All the CT images were retrospectively analyzed by two radiologists in consensus,based on their description of morphology(location,number,size,margin and fibrous capsule) and enhancement patterns of masses.In addition,the diagnostic efficiency of diagnostic strategy is tested.RESULTS:War-T and BCA patients' mean age was 59.9 ± 12.6 years and 58.4 ± 18.2 years;the significant difference was seen in War-T vs PA and BCA vs PA.About 40% of War-Ts presented with bilateral multifocal lesions,a higher ratio than others.Seventy two percent of War-Ts were limited to the superficial lobe,followed by BCA 60% and PA 40%.Vessel facing sign and enlarged lymph nodes were both frequent in War-T,which respectively accounts for 84% and 76% of cases.Rapid contrast enhancement and decreases were unique for War-T.BCA and PA showed obvious delayed enhancement.The diagnostic strategy of parotid gland tumor had a good diagnostic efficiency,with high accuracy,sensitivity and specificity.CONCLUSION:Determination of the histological subtypes of parotid gland masses might be possible based on CT findings and clinical data.A diagnostic strategy with high diagnostic efficiency was established. | Zhi-Feng Xu Fang Yong Tian Yu Ying-Yu Chen Qiang Gao Tao Zhou Ai-Zhen Pan Ren-Hua Wu | 2013 | World Journal of Radiology2013，5，8： | 25 |
| 10 | Trends in particulate matter and its chemical compositions in China from 2013–2017显示文摘Accurate determination of the atmospheric particulate matter mass concentration and chemical composition is helpful in exploring the causes and sources of atmospheric enthalpy pollution and in evaluating the rationality of environmental air quality control strategies.Based on the sampling and chemical composition data of PM2.5 in different key regions of China in the CARE-China observation network,this research analyzes the environmental air quality data released by the China National Environmental Monitoring Centre during the studied period to determine the changes in the particulate matter mass concentration in key regions and the evolution of the corresponding chemical compositions during the implementation of the Action Plan for Prevention and Control of Air Pollution from 2013-2017.The results show the following.(1)The particulate matter mass concentration in China showed a significant downward trend;however,the PM2.5 annual mass concentration in 64%of cities exceeds the New Chinese Ambient Air Quality Standard(CAAQS)GradeⅡ(GB3095-2012).The region to the east of the Taihang Mountains,the Fenhe and Weihe River Plain and the Urumqi-Changji regions in Xinjiang,all have PM2.5 concentration loading that is still high,and heavy haze pollution occurred frequently in the autumn and winter.(2)During the heavy pollution in the autumn and winter,the concentrations of sulfate and organic components decreased significantly.The mean SO42-concentration in PM2.5 decreased by 76%,12%,81%and 38%in Beijing-Tianjin-Hebei(BTH),the Pearl River Delta(PRD),the Sichuan-Chongqing region(SC)and the Fenhe and Weihe River Plain,respectively.The mean organic matter(OM)concentration decreased by 70%,44%,48%and 31%,respectively,and the mean concentration of NH4+decreased by 68%,1.6%,38%and 25%,respectively.The mean elemental carbon(EC)concentration decreased by 84%and 20%in BTH and SC,respectively,and it increased by 61%and 11%in the PRD and Fenhe and Weihe River Plain,respectively.The mean concentration of mineral and unresolved chemical components(MI)dropped by 70%,24%and 13%in BTH,the PRD and the Fenhe and Weihe River Plain,respectively.The change in the PM2.5 chemical composition is consistent with the decrease of the PM2.5mass concentration.(3)In 2015,the mean OM concentration contributions to fine particles and coarse particles were 13-46%and 46-57%,respectively,and the mean MI concentration contributions to fine particles and coarse and particles were 31-60%and 39-73%,respectively;these values are lower than the 2013 values from the key regions,which is the most important factor behind the decrease of the particulate matter mass concentration.From 2013 to 2015,among the chemical components of different particle size fractions,the peak value of the coarse particle size fraction decreased significantly,and the fine particle size fractions of SO42-,NO3-,and NH4+decreased with the decrease of the particulate matter mass concentration in different particle size fractions.The fine-particle size peaks of SO42-,NO3-and NH4+shifted from 0.65-1.1μm to the finer size range of0.43-0.65μm during the same time frame. | Yuesi WANG Wenjie LI Wenkang GAO Zirui LIU Shili TIAN Rongrong SHEN Dongsheng JI Shuai WANG Lili WANG Guiqian TANG Tao SONG Mengtian CHENG Gehui WANG Zhengyu GONG Jiming HAO Yuanhang ZHANG | 2019 | Science China Earth Sciences2019，62，12： | 23 |
| 11 | Baicalin induces ferroptosis in bladder cancer cells by downregulating FTH1显示文摘Ferroptosis is a non-apoptotic regulated cell death caused by iron accumulation and subsequent lipid peroxidation.Currently,the therapeutic role of ferroptosis on cancer is gaining increasing interest.Baicalin an active component in Scutellaria baicalensis Georgi with anticancer potential various cancer types;however,the effects of baicalein on bladder cancer and the underlying molecular mechanisms remain largely unknown.In the study,we investigated the effect of baicalin on bladder cancer cells5637 and KU-19-19.As a result,we show baicalin exerted its anticancer activity by inducing apoptosis and cell death in bladder cancer cells.Subsequently,we for the first time demonstrate baicalin-induced ferroptotic cell death in vitro and in vivo,accompanied by reactive oxygen species(ROS) accumulation and intracellular chelate iron enrichment.The ferroptosis inhibitor deferoxamine but not necrostatin-1,chloroquine(CQ),N-acetyl-L-cysteine,L-glutathione reduced,or carbobenzoxy-valyl-alanyl-aspartyl-[O-methyl]-fluoromethylketone(Z-VAD-FMK) rescued baicalin-induced cell death,indicating ferroptosis contributed to baicalin-induced cell death.Mechanistically,we show that ferritin heavy chain1(FTH1) was a key determinant for baicalin-induced ferroptosis.Overexpression of FTH1 abrogated the anticancer effects of baicalin in both 5637 and KU19-19 cells.Taken together,our data for the first time suggest that the natural product baicalin exerts its anticancer activity by inducing FTH1-dependent ferroptosis,which will hopefully provide a prospective compound for bladder cancer treatment. | Na Kong Xiaying Chen Jiao Feng Ting Duan Shuiping Liu Xueni Sun Peng Chen Ting Pan Lili Yan Ting Jin Yu Xiang Quan Gao Chengyong Wen Weirui Ma Wencheng Liu Mingming Zhang Zuyi Yang Wengang Wang Ruonan Zhang Bi Chen Tian Xie Xinbing Sui Wei Tao | 2021 | Acta Pharmaceutica Sinica B2021，11，12： | 23 |
| 12 | Study of the ionospheric anomaly before the Wenchuan earthquake显示文摘The behavior of the ionosphere before the Wenchuan earthquake is analyzed with the global TEC and ionospheric foF2 observed at Xiamen. It can be found from TEC maps that in the afternoon (16―18LT) on May 9, 2008, 3 days before the earthquake, there is an enhancement of TEC with an amplitude of 10―15 TECU appearing in the east-south direction of Wenchuan, and another enhancement appears at the conjugate region of the Southern Hemisphere with an amplitude of 10 TECU, but no obvious in-crement or decrement can be seen in other regions on global scale. It can also be found that on May 6 (6 days before the great earthquake), there is a decrement of TEC with small amplitude of 4TECU and larger area with 80° along the longitude in southern China, and there is no synchronous decrement observed at the conjugate region of the Southern Hemisphere. There are also many anomalies ob-served by ionosondes across China. The result shows that foF2 and TEC abnormally increased, which is different from pervious results that ionospheric parameters decreased prior to earthquakes. Pre-liminary results suggest that the enhancement on May 9 maybe has a close relationship with the pos-sible enhancement of ionospheric electric fields, and it may be an ionospheric precursor of earth-quakes. Whereas the decrement on May 6 may be attributed to the geomagnetic disturbance appearing on May 5. | YU Tao MAO Tian WANG YunGang WANG JingSong | 2009 | Chinese Science Bulletin2009，54，6： | 20 |
| 13 | Gravity Flow on Slope and Abyssal Systems in the Qiongdongnan Basin,Northern South China Sea显示文摘新地震数据的学习在架并且在 Qiongdongnan 盆(QDNB ) 的深渊的设定上以内部建筑学和分发允许沉积严肃流动的鉴定。六种严肃流动类型被认出:(1 ) 有基础、一致的 truncational 的 turbidite 隧道压垂沿着架边和斜坡的关系,包括旁边地转移、使河床升高得垂直地的隧道建筑群;(2 ) 有塑造汤勺的形态学的滑坡在架裂缝上滑动步并且从变丑产生了糟糕巩固并且高水位线内容沉积;(3 ) 商业萧条在架斜坡上被限制,由一个异常斜坡坡度或由差错活动被触发;(4 ) turbidite 表建筑群(TSC ) 被归功于到盆地板扇子和斜坡扇子起源,偶尔由混浊水流喂深海洋的存款;(5 ) 沉积飘动在更低的斜坡盆地板发生,并且盖住约 400 km2 的一个区域,在越过海床流动的水流下面被产生;并且(6 ) 在深水区域的中央峡谷表示严肃流动的一种例外的类型碎片流动, turbidite 隧道,和 TSC 的一个协会创作了。它介绍平面 multisegment 和垂直多相的特征。在峡谷与好 petrophysical 性质联系的 Turbidite 能在 QDNB 被当作一个潜在的探索目标。 | SU Ming XIE Xinong LI Junliang JIANG Tao ZHANG Cheng HE Yunlong TIAN Shanshan ZHANG Cuimei | 2011 | Acta Geologica Sinica(English Edition)2011，85，1： | 19 |
| 14 | Comparison of glycemic variability and glycated hemoglobin as risk factors of coronary artery disease in patients with undiagnosed diabetes显示文摘背景一个冠的动脉疾病( CAD )风险因素是著名的长期的多糖症的角色,并且 glycemic 可变性仍然是这研究的 debate.The 目的一件事是调查承认 glycemic 的协会有在有 undiagnosed 糖尿病 mellitus ( DM )的病人的 CAD 的存在和严厉的旅行和血红素 A1c ( HbA1c )我们学习了的 .Methods 286 最新诊断了 DM 没有优先的 revascularization 的病人为怀疑的 ischaemic ch 经历冠的 | MI Shu-hua SU Gong LI Zhao YANG Hong-xia ZHENG Hong TAO Hong ZHOU Yun TIAN Lei | 2012 | Chinese Medical Journal2012，，1： | 18 |
| 15 | Effect of pre-electroacupuncture on p38 and c-Fos expression in the spinal dorsal horn of rats suffering from visceral pain显示文摘背景针灸是减轻 electroacupuncture (EA ) 由减少的疼痛,而是机制的一个有效方法内脏的疼痛状态仍然保持不清楚。这研究试图在结肠的墙和患内脏的疼痛的老鼠的针的背面的角中在疼痛行为, p38 phosphorylation,和 c-Fos 蛋白质和 mRNA 表示上评估 pre-electroacupuncture 的效果。这研究也调查了 electroacupuncture 导致的止痛效果的可能的发信号的规章的机制。所有老鼠被使随机化进组, Con+EA 组,内脏的疼痛(VP ) 组,和 VP+EA 组织的控制(反对)( 为所有组的 n=8 ) 的方法。内脏的疼痛模型用注入老鼠的结肠的 5% 福尔马林答案的 40 ul 被建立。EA 在内脏的疼痛的申请前被用于双边的 Jiaji acupoints 20 分钟。为 EA 的参数被放在一个连续波浪(20 Hz ) 和老鼠摇了他们的络腮胡子的紧张,但是没扒寻(1 个妈) 。内脏的疼痛分数被记录, p38 和 c-Fos 蛋白质的表情用西方的弄污被检测。实时量的 PCR 也被用来决定 c-Fos mRNA 的表示。在立即在与福尔马林被注射以后与明显的内脏的疼痛行为介绍的 VP 组的结果老鼠。在结肠的墙和针的背面的角中的 p38 活动和 c-Fos 蛋白质和 mRNA 表示比在反对组在 VP 组是更高的(P < 0.05 ) 。由对比,内脏的疼痛行为从 VP+EA 组在老鼠被推迟。p38 活动和 c-Fos 蛋白质和 mRNA 表示在 VP 组比那在 VP+EA 组是更低的(P < 0.01 ) 。Jiaji acupoint 的结论 Pre-electroacupuncture 在患内脏的疼痛的老鼠上有预防止痛效果。p38 信号 transduction 小径可以部分涉及这止痛效果的规章的机制。 | XU Ke-da LIANG Tao WANG Kun TIAN De-an | 2010 | Chinese Medical Journal2010，，9： | 15 |
| 16 | Impacts of climate variability and extremes on global net primary production in the first decade of the 21st century显示文摘许多研究估计了全球陆上的网的大小主要生产(NPP ) ,而是它的变化,空间地并且时间地,仍然保持不明确。由使用一个改进基于过程的陆上的生态系统模型( DLEM ,动态陆地生态系统模型),我们提供多重环境因素导致的全球陆上的 NPP 的估计并且在整个 第21 世纪的第一十年在生物群系和全球层次并且沿着纬度检验陆上的 NPP 的反应到气候可变性。模型模拟在 20002009 期间估计 54.6 Pg C 年 1 的平均全球陆上的 NPP,从 2002 ~ 56.4 Pg C 的干燥的年里的 52.8 Pg C 年 1 变化 2008 的湿年里的年 1 。在湿年里,与十的平均数相比的陆上的 NPP 的大增加在 Amazonia,非洲和澳大利亚是流行的。在干燥的年里,然而,我们与十的平均数相比在全球陆上的 NPP 发现了 3.2% 减小,首先由于在热带区域的有限潮湿供应。在全球水平,降水在陆上的 NPP 解释了约 63% 变化,当剩余的在温度和另外的环境因素被归因于变化时。降水是在低纬度的区域在陆上的 NPP 决定内部年度的变化的主要因素。在中间纬度、高纬度的区域,然而,温度可变性大部分控制了陆上的 NPP 的大小。我们的结果暗示温暖并且增加气候极端事件的那投射气候将改变大小和全球陆上的 NPP 的空间与时间的模式。 | PAN Shufen TIAN Hanqin DANGAL Shree R.S. OUYANG Zhiyun LU Chaoqun YANG Jia TAO Bo REN Wei BANGER Kamaljit YANG Qichun ZHANG Bowen | 2015 | Journal of Geographical Sciences2015，25，9： | 15 |
| 17 | Feasibility of endoscopic treatment and predictors of lymph node metastasis in early gastric cancer显示文摘BACKGROUND Endoscopic submucosal dissection (ESD) has been routinely performed in applicable early gastric cancer (EGC) patients as an alternative to conventional surgical operations that involve lymph node dissection. The indications for ESD have been recently expanded to include larger, ulcerated, and undifferentiated mucosal lesions, and differentiated lesions with slight submucosal invasion. The risk of lymph node metastasis (LNM) is the most important consideration when deciding on a treatment strategy for EGC. Despite the advantages over surgical procedures, lymph nodes cannot be removed by ESD. In addition, whether patients who meet the expanded indications for ESD can be managed safely remains controversial. AIM To determine whether the ESD indications are applicable to Chinese patients and to investigate the predictors of LNM in EGC. METHODS We retrospectively analyzed 12552 patients who underwent surgery for gastric cancer between June 2007 and December 2018 at the Affiliated Hospital of Qingdao University. A total of 1262 (10.1%) EGC patients were eligible for inclusion in this study. Data on the patients’ clinical, endoscopic, and histopathological characteristics were collected. The absolute and expanded indications for ESD were validated by regrouping the enrolled patients and determining the positive LNM results in each subgroup. Predictors of LNM in patients were evaluated by univariate and multivariate analyses. RESULTS LNM was observed in 182 (14.4%) patients. No LNM was detected in the patients who met the absolute indications (0/90). LNM occurred in 4/311 (1.3%) patients who met the expanded indications. According to univariate analysis, LNM was significantly associated with positive tumor marker status, medium (20-30 mm) and large (>30 mm) lesion sizes, excavated macroscopic-type tumors, ulcer presence, submucosal invasion (SM1 and SM2), poor differentiation, lymphovascular invasion (LVI), perineural invasion, and diffuse and mixed Lauren’s types. Multivariate analysis demonstrated SM1 invasion (odds ration [OR]= 2.285, P = 0.03), SM2 invasion (OR = 3.230, P < 0.001), LVI (OR = 15.702, P < 0.001), mucinous adenocarcinoma (OR = 2.823, P = 0.015), and large lesion size (OR = 1.900, P = 0.006) to be independent risk factors. CONCLUSION The absolute indications for ESD are reasonable, and the feasibility of expanding the indications for ESD requires further investigation. The predictors of LNM include invasion depth, LVI, mucinous adenocarcinoma, and lesion size. | Yu-Ning Chu Ya-Nan Yu Xue Jing Tao Mao Yun-Qing Chen Xiao-Bin Zhou Wen Song Xian-Zhi Zhao Zi-Bin Tian | 2019 | World Journal of Gastroenterology2019，25，35： | 15 |
| 18 | An Ant Colony Algorithm Based on Cross-Layer Design for Routing and Wavelength Assignment in Optical Satellite Networks显示文摘This paper introduces an ant colony routing and wavelength assignment algorithm based on cross-layer design(CL-ACRWA),which can overcome the adverse effects of Doppler wavelength shift on data transmission in optical satellite networks. Firstly, a cross-layer optimization model is built, which considers the Doppler wavelength shift, the transmission delay as well as wavelength-continuity constraint. Then an ant colony algorithm is utilized to solve the cross-layer optimization model, resulting in finding an optimal light path satisfying the above constraints for every connection request. The performance of CL-ACRWA is measured by the communication success probability, the convergence property and the transmission delay. Simulation results show that CL-ACRWA performs well in communication success probability and has good global search ability as well as fast convergence speed. Meanwhile, the transmission delay can meet the basic requirement of real-time transmission of business. | Guoli Wen Qi Zhang Houtian Wang Qinghua Tian Ying Tao | 2017 | China Communications2017，14，8： | 14 |
| 19 | Changes in China’s lakes: climate and human impacts显示文摘Lakes have played a critical role in providing water and ecosystem services for people and other organisms in China for millennia.However,accelerating climate change and economic boom have resulted in unprecedented changes in these valuable lakes.Using Landsat images covering the entity of the country,we explored the changes in China’s lakes and the associated driving forces over the last 30 years(i.e.mid-1980 s to 2015).We discovered that China’s lakes have changed with divergent regional trends:in the sparsely populated Tibetan Plateau,lakes are abundant and the lake area has increased dramatically from 38596 to46831 km^2(i.e.increased by 8235 km^2,or 21.3%),whereas,in the densely populated northern and eastern regions,lakes are relatively scarce and the lake area has decreased from 36659 to 33657 km^2(i.e.decreased by 3002 km^2,or 8.2%).In particular,severe lake decreases occurred in the Mongolia-Xinjiang Plateau and the Eastern Plain(-2151 km^2).Statistical analyses indicated that climate was the most important factor controlling lake changes in the Tibetan Plateau,the Yun-Gui Plateau and the Northeast Plain.However,the strength of climatic control on lake changes was low in the Eastern Plain and the Mongolia-Xinjiang Plateau,where human activities,e.g.impoldering,irrigation and mining,have caused serious impacts on lakes.Further lake changes will exacerbate regional imbalances between lake resources and population distribution,and thus may increase the risk of water-resource crises in China. | Shengli Tao Jingyun Fang Suhui Ma Qiong Cai Xinyu Xiong Di Tian Xia Zhao Leqi Fang Heng Zhang Jiangling Zhu Shuqing Zhao | 2020 | National Science Review2020，7，1： | 14 |
| 20 | Teleportation of an arbitrary two-qudit state based on the non-maximally four-qudit cluster state显示文摘Two different schemes are presented for quantum teleportation of an arbitrary two-qudit state using a non-maximally four-qudit cluster state as the quantum channel. The first scheme is based on the Bell-basis measurements and the re-ceiver may probabilistically reconstruct the original state by performing proper transformation on her particles and an auxiliary two-level particle; the second scheme is based on the generalized Bell-basis measurements and the probability of successfully teleporting the unknown state depends on those measurements which are adjusted by Alice. A comparison of the two schemes shows that the latter has a smaller probability than that of the former and contrary to the former, the channel information and auxiliary qubit are not necessary for the receiver in the latter. | TIAN DongPing TAO YingJuan QIN Meng | 2008 | Science China(Physics,Mechanics & Astronomy)2008，51，10： | 14 |
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