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| 1 | CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development显示文摘Angiogenesis,最新形成的血容器从先存在发芽的一个过程,为脊椎动物开发和成年动态平衡是重要的。以前的研究证明了 neuronal 指导分子 netrin-1 参予脉管的系统的 angiogenesis 和形态发生。Netrin-1 在 angiogenesis 展出双活动:支持或禁止 angiogenesis。netrin-1 的 anti-angiogenic 活动被 UNC5B 受体调停。然而, netrin-1 怎么支持 angiogenesis,仍然保持不清楚。这里,我们报导那 CD146,免疫球蛋白总科的 endothelial transmembrane 蛋白质,是为 netrin-1 的受体。Netrin-1 与高亲密关系绑在 CD146,导致 endothelial 房间激活并且以一种 CD146 依赖的方式的下游的发信号。在由特定的 anti-CD146 抗体的 netrin-CD146 相互作用的鼠科的内皮细胞层或混乱的 cd146 基因的有条件的大美人堵住或减少 netrin-1-induced angiogenesis。在 zebrafish 胚胎, downregulating 任何一个 netrin-1a 或 CD146 与惹人注目的类似导致脉管的缺点。而且,将宫外的脉管的发芽由 netrin-1 overexpression 导致了的 CD146 块击倒。一起,我们的数据揭开 CD146 在 angiogenesis 为 CD146 作为为 netrin-1 并且也的以前未知的受体揭示功能的 ligand,表明在脊椎动物开发期间在 angiogenesis 发信号的 netrin-CD146 的参与。 | Tao Tu Chunxia Zhang Huiwen Yan Yongting Luo Ruirui Kong Pushuai Wen Zhongde Ye Jianan Chen Jing Feng Feng Liu Jane Y Wu Xiyun Yan | 2015 | Cell Research2015，25，3： | 23 |
| 2 | Association of farnesyl diphosphate synthase polymorphisms and response to alendronate treatment in Chinese postmenopausal women with osteoporosis显示文摘 | Liu Y Li M Zhou PR Xing XP Xia WB Xu L Liu H J Zhang ZL LiaoEY Chen DC Liu J Tao TZ Wu W | 2014 | Chinese Medical Journal2014，，4： | 16 |
| 3 | Paleoproterozoic basement beneath the southern Jiangxi Province:Evidence from U-Pb ages and Lu-Hf isotopes in zircons from the Doushui lamprophyre显示文摘这篇论文论述侵入的煌斑岩的 geochemical 分析在 Shangyou 县的古苏格兰的 Doushui 花岗石身体,南部的江西省。U-Pb 标明日期和 Hf 同位素分析特别从它为锆石被执行。Petrological 和 geochemical 特征证明煌斑岩属于 high-K,弱碱的辉石黑云母煌斑岩。它被 Mg #(0.74 ) , Ni (253 μg/g ) 和 Cr (893 μg/g ) 满足的高度描绘,并且也在不兼容的元素充实,例如 REE, Rb, Sr, Ba 和 K。它的原语融化,这被建议可能由 non-crust-derived 源于充实的披风 metasomatized 代理人。在煌斑岩标明日期锆石的结果的形态学和 LAM-ICPMS 显示他们是从深外壳的岩石捕获的 xenocrysts。在 ∼1.86 Ga 形成的大多数 xenocrystic 锆石,和在不同 Phanerozoic 时期的一些。Paleoproterozoic 锆石具有 magmatic 起源并且有类似的 176Hf/177 Hf 和 176Lu/177 Hf 比率,显示他们可能从一样的火的地下室岩石。年龄和从这地下室岩石的锆石的 Hf 同位素作文类似于在南部的浙江省的 Paleoproterozoic Danzhu 花岗石的那些,但是极其与 Nanling 地下室区分开来,建议学习区域可能是一向西在东方卡赛西亚·布洛克的 Paleoproterozoic Wuyishan 岩层的延期部分。这些 Paleoproterozoic 锆石有低 Hf 同位素作文,外壳的来源特征。这些锆石的 Hf 模型年龄和在他们以内的更旧的继承核心的存在,结合了可得到的其它数据由以前的研究报导了,建议 Paleoproterozoic 岩浆的来源是 Neoarchaean 外壳,在 Wuyishan 岩层暗示更旧的地下室的存在。U-Pb 年龄和五 Phanerozoic 锆石的 Hf 同位素显示那个 Paleoproterozoic 地下室经历了多重做的发生在古苏格兰, Indosinian 和早 Yanshanian 分别地。古苏格兰的 magmatism 也涉及少年外壳重做。 | YU JinHai WANG LiJuan O'REILLY S Y SHU LiangShu SUN Tao | 2009 | Chinese Science Bulletin2009，54，9： | 10 |
| 4 | 睡眠时间和质量与心血管疾病、癌症和死亡率的关系显示文摘瞪眠是人体重要的一项身体机能,对人类健康至关重要。近年来,睡眠时间和睡眠质量对健康结果的影响受到了相当大的关注。为评储睡配时问民短的独立凤险阿素。以及与心血管疾病、癌症和死亡率相关的较差的睡眠特征,研究人员进行了一项平均随访时长中位数为8.57年的前瞻性队列研究。 | 李晨阳(译) Tao F Cao Z Jiang Y | 2021 | 中华医学杂志2021，101，22： | 5 |
| 5 | Hepatitis C virus RNA and antibodies among blood donors in Beijing 显示文摘 | Wang Y Tao QM Zhao HY | 1994 | J Hepatol1994，21，4： | 4 |
| 6 | Randomised controlled trial comparing modified Sano's and narrow band imaging international colorectal endoscopic classifications for colorectal lesions显示文摘AIM To assess the utility of modified Sano′s(MS) vs thenarrow band imaging international colorectal endoscopic(NICE) classification in differentiating colorectal polyps.METHODS Patients undergoing colonoscopy between 2013 and 2015 were enrolled in this trial.Based on the MS or the NICE classifications,patients were randomised for real-time endoscopic diagnosis.This was followed by biopsies,endoscopic or surgical resection.The endoscopic diagnosis was then compared to the final(blinded) histopathology.The primary endpoint was the sensitivity(Sn),specificity(Sp),positive predictive value(PPV) and negative predictive value(NPV) of differentiating neoplastic and non-neoplastic polyps(MSⅡ/Ⅱo/Ⅲa/Ⅲb vs I or NICE 1 vs 2/3).The secondary endpoints were 'endoscopic resectability'(MSⅡ/Ⅱo/Ⅲa vs Ⅰ/Ⅲb or NICE 2 vs 1/3),NPV for diminutive distal adenomas and prediction of post-polypectomy surveillance intervals.RESULTS A total of 348 patients were evaluated.The Sn,Sp,PPV and NPV in differentiating neoplastic polyps from non-neoplastic polyps were,98.9%,85.7%,98.2% and 90.9% for MS;and 99.1%,57.7%,95.4% and 88.2% for NICE,respectively.The area under the receiver operating characteristic curve(AUC) for MS was 0.92(95%CI:0.86-0.98);and AUC for NICE was 0.78(95%CI:0.69,0.88).The Sn,Sp,PPV and NPV in predicting 'endoscopic resectability' were 98.9%,86.1%,97.8% and 92.5% for MS;and 98.6%,66.7%,94.7% and 88.9% for NICE,respectively.The AUC for MS was 0.92(95%CI:0.87-0.98);and the AUC for NICE was 0.83(95%CI:0.75-0.90).The AUC values were statistically different for both comparisons(P = 0.0165 and P = 0.0420,respectively).The accuracy for diagnosis of sessile serrated adenoma/polyp(SSA/P) with high confidence utilizing MS classification was 93.2%.The differentiation of SSA/P from other lesions achieved Sp,Sn,PPV and NPV of 87.2%,91.5%,89.6% and 98.6%,respectively.The NPV for predicting adenomas in diminutive rectosigmoid polyps(n = 150) was 96.6% and 95% with MS and NICE respectively.The calculated accuracy of post-polypectomy surveillance for MS group was 98.2%(167 out of 170) and for NICE group was 92.1%(139 out of 151).CONCLUSION The MS classification outperformed the NICE classification in differentiating neoplastic polyps and predicting endoscopic resectability.Both classifications met ASGE PIVI thresholds. | Leonardo Zorrón Cheng Tao Pu Kuan Loong Cheong Doreen Siew Ching Koay Sze Pheh Yeap Amanda Ovenden Mahima Raju Andrew Ruszkiewicz Philip W Chiu James Y Lau Rajvinder Singh | 2018 | World Journal of Gastrointestinal Endoscopy2018，10，9： | 4 |
| 7 | Microstructure and evolution of mechanically-induced ultrafine grain in surface layer of AL-alloy subjected to USSP显示文摘 | X Wu N Tao Y Hong B Xu J Lu K Lu | 2002 | Acta Materialia2002，，8： | 3 |
| 8 | High Nitrogen Steel Powder for NearNet Shape Products 显示文摘 | Tao Y Gammal T El | 1999 | Steel Research1999，70，45： | 2 |
| 9 | Outcome of intravitreal bevacizumab for id- iopathic choroidal neovascularization in the Chinese population 显示文摘 | Qi H J Li XX Tao Y | 2010 | Can J Ophthalmol2010，45，4： | 1 |
| 10 | Learning vector quantization for color classification of diseased air sacs in chicken carcasses 显示文摘 | Ibarra J G Tao Y Newberry B L | 2002 | Transation of the ASAE2002，45，5： | 1 |
| 11 | Description of distributed features of the nestin - containing cells in brains of adult mice: a potential source of neural precursor cells 显示文摘 | Xu R Wu C Tao Y | 2010 | J Neurosci Res2010，88，5： | 1 |
| 12 | Polycyclic aromatic hydrocarbons in agricultural soil and vegetables from Tianjin 显示文摘 | Tao S Cui Y H Xu F L | 2004 | Sci Total Environ2004，320，： | 1 |
| 13 | A numerical model for phase change suspension flow in microchannels显示文摘 | HAO Y L TAO Y -X | 2004 | Numerical Heat Transfer:A2004，46，1： | 1 |
| 14 | Reduced arterial elasticity is associated with endothelial dysfunction in persons of advancing age: comparative study of noninvasive pulse wave analysis and laser dopper blood flow measurement显示文摘 | TAO J JIN Y F YANG Z | 2004 | Am J Hypertens2004，17，： | 1 |
| 15 | Atomic states, potential energies, volumes, stability and brittleness of ordered FCC TiAl2 type alloys显示文摘 | Xie Y Q Tao H J Peng H J | 2005 | Physica B2005，366，： | 1 |
| 16 | Preparative separation and purification of rosavin in Rhodiola rosea by macroporous adsorption resins显示文摘 | Ma C Y Tao G J Tang J | 2009 | Separation and Purification Technology2009，，69： | 1 |
| 17 | A new class of transcription factors mediates brassinosteroid regulated gene expression in Arabidopsis显示文摘 | YIN Y VAFEADOS D TAO Y | 2005 | Cell2005，120，： | 1 |
| 18 | Experimental Behaviour of High Performance Concrete-Filled Steel Tubular Columns 显示文摘 | Yu Q Tao Z Wu Y X | 2008 | Thin- Wailed Structures2008，46，4： | 1 |
| 19 | Whole rDNA analy- sis reveals novel and endophytic fungi in BletiUa ochracea (Orehidaceae) 显示文摘 | TAO G LIU Z Y HYDE K D | 2008 | Fungal Divers2008，33，1： | 1 |
| 20 | Game Theoretic Multimode Precoding Strategy Selection for MIMO Multiple Access Channels显示文摘 | ZHONG W XU Y Y TAO M X | 2010 | IEEE Signal Processing Letters2010，17，06： | 1 |
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