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| 1 | 接受他汀治疗患者新发糖尿病风险:人群为基础的研究显示文摘目的 研究接受HMG-CoA还原酶抑制剂(他汀类药物)治疗的患者的新发糖尿病风险。设计 人群为基础的队列研究,以时间事件分析的方法评估各种他汀类药物应用和新发糖尿病风险的相关性分析。计算危害比(hazard ratios,HR)来确定他汀的种类及剂量与新发糖尿病的关系。 | Aleesa A Caner Tara Gomes Ximena Camacho David N Juurlink Baiju R Shah Muhammad M Mamdani 张秀珍(译) 骆斯慧(译) 翁建平(校) | 2013 | 英国医学杂志中文版2013，16，5： | 2 |
| 2 | 在有煽动性、非煽动性的腹的疼痛显型的孩子的 interleukin-6 和桅杆房间的反的关系显示文摘 AIM: To investigate interleukin-6 (IL-6), mast cells, enterochromaffin cells, 5-hydroxytryptamine, and substance P in the gastrointestinal mucosa of children with abdominal pain. METHODS: Formalin-fixed paraffin-embedded gas-trointestinal biopsy blocks from patients (n = 48) with non-inflammatory bowel disease (irritable bowel syndrome and functional abdominal pain) and inflammatory bowel disease were sectioned and stained for IL-6, mast cells, enterochromaffin cells, 5-hydroxytryptamine, and substance P. All children had chronic abdominal pain as part of their presenting symptoms. Biopsy phenotype was confirmed by a pathologist, blinded to patient information. Descriptive statistics, chi-square, and independent sample t tests were used to compare differences between the inflammatory and non-inflammatory groups. RESULTS: The cohort (n = 48), mean age 11.9 years (SD = 2.9), 54.2% females, 90% Caucasian, was comprised of a non-inflammatory (n = 26) and an inflammatory (n = 22) phenotype. There was a significant negative correlation between substance P expression and mast cell count (P = 0.05, r = -0.373). Substance P was found to be expressed more often in female patient biopsies and more intensely in the upper gastrointestinal mucosa as compared to the lower mucosa. There were significantly increased gastrointestinal mucosal immunoreactivity to IL-6 (P = 0.004) in the inflammatory phenotype compared to non-inflammatory. Additionally, we found significantly increased mast cells (P = 0.049) in the mucosa of the non-inflammatory phenotype compared to the inflammatory group. This difference was particularly noted in the lower colon biopsies. CONCLUSION: The findings of this study yield preliminary evidence in identifying biomarkers of undiagnosed abdominal pain in children and may suggest candidate genes for future evaluation. | Wendy A Henderson Ravi Shankar Tara J Taylor Arseima Y Del Valle-Pinero David E Kleiner Kevin H Kim Nader N Youssef | 2012 | World Journal of Gastrointestinal Pathophysiology2012，3，6： | 2 |
| 3 | Titanium dioxide photocatalysis 显示文摘 | Akira F Tara N R Donald A T | 2000 | Journal of Photochemistry and Photobiology C: Photochemistry Reviews2000，1，： | 1 |
| 4 | A population-based study of the drug interaction between proton pump inhibitors and clopidogrel显示文摘 | Juurlink David N Gomes Tara Ko Dennis T Szmitko Paul E Austin Peter C Tu Jack V Henry David A Kopp Alex Mamdani Muhammad M | 2009 | Canadian Medical Association. Journal2009，，7： | 1 |
| 5 | A population-based study of the drug interaction between proton pump inhibitors and clopidogrel显示文摘 | David N Juurlink MD PhD Tara Gomes MHSc | 2009 | CMAJ2009，80，7： | 1 |
| 6 | Bicalutamide (Casodex)-induced prostate regression involves increased expression of genes encoding insulin-like growth factor binding proteins显示文摘 | Michael P | 1999 | Urology1999，54，6： | 1 |
| 7 | Proton magnetic resonance spectroscopy study of brain metabolite changes af- ter antipsychotic treatment 显示文摘 | Szulc A Gali n iska B Taras o w E | 2011 | Pharmacopsychiatry2011，44，4： | 1 |
| 8 | Titanium Dioxide Photocalalyis 显示文摘 | Fujishima A Tara N Rao Donald A | 2000 | Journal of Photochemistry and Photobiology C:Photochemiscy Reviews2000，1，： | 1 |
| 9 | The relative importance of specific self-effi- cacy sources in pretraining self-efficacy beliefs显示文摘 | Garett N Tara S | 2015 | Intemational Journal of Training & Development2015，19，4： | 1 |
| 10 | Crosslinking kinetics of methyl and ethyl ( a - hydroxymethyl ) acrylates : effect of crosslinker type and functionality 显示文摘 | TARA J S BIANCA S S JENNIFER S N | 2003 | Polymer2003，44，： | 1 |
| 11 | Aberrant microsporogenesis and sterility in Impatiens sultani (Balsaminaceae)显示文摘 | TARA C P NAMBOODRI A N | 1974 | American Journal of Botany1974，61，6： | 1 |
| 12 | Direct comparison of nanoindentation and macroscopic measurements of bone viscoelasticity显示文摘 | Tara N S Jingzhou Zhang Timothy C O | 2011 | Journal of the Mechanical Behavior of Biomedical Material2011，4，： | 1 |
| 13 | Per- ception of Deqi by Chinese and American acupuncturists : a pi- lot survey显示文摘 | Kathleen KKS Hui Tara N Sporko Mark G Vangel | 2011 | Chinese Medicine2011，6，： | 1 |
| 14 | Critical role for miR-181ab-1 in agonist selection of invariant natural killer T cells显示文摘 | Zietara N yszkiewicz M Witzlau K | 2013 | Proc Natl Acad Sci USA2013，110，： | 1 |
| 15 | H-prune-nm23-H1 protein complex and correlation to pathways in cancer metastasis显示文摘 | Garzia L Roma C Tara N | 2006 | J Bioenerg Bi- omembr2006，38，34： | 1 |
| 16 | Root traits as tools for creating phosphorus efficient crop varieties显示文摘 | Tara S G Niels E N | 2004 | Plant Soil2004，，260： | 1 |
| 17 | A population-based study of the drug interaction between proton pump inhihiters and clopidogrel显示文摘 | David N Juurlink Tara Gomes Dennis T Ko | 2009 | Can Med Assoc J2009，180，7： | 1 |
| 18 | Rates of hemorrhage during warfarin therapy for atrial fibrillation显示文摘 | Gomes Tara Mamdani Muhammad M Holbrook Anne M Paterson J Michael Hellings Chelsea Juurlink David N | 2013 | Canadian Medical Association. Journal2013，，2： | 1 |
| 19 | Selective serotonin reuptake inhibitors and breast cancer mortality in women receiving tamoxifen: a population based cohort study 显示文摘 | Catherine M Kelly David N Juurlink Tara Gomes | 2010 | BMJ2010，340，： | 1 |
| 20 | ,Per- ception of Deqi by Chinese and American acupuncturists: a pilot survey显示文摘 | Kathleen KKS Hui Tara N Sporko Mark G Vangel | 2011 | Chin Med2011，6，1： | 1 |
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