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| 1 | Long-term albumin infusion improves survival in patients with cirrhosis and ascites: An unblinded randomized trial显示文摘瞄准:在幸存上调查长期的白朊管理的效果,腹水的复发和另外的复杂并发症的发作。方法:为第一发作的腹水招收的 100 个连续病人被使随机化加人的白朊收到利尿剂第一年和 25 g 里的 25 g/wk 每二 wk 此后(组 1 ) 或利尿剂独自一个(组 2 ) 。没有肝移植,主要端点是幸存。第二等的端点是腹水的复发和另外的复杂并发症的出现。结果:中部的后续是 84 (2-120 ) 瞬间。对待白朊的病人有显著地更大的累积幸存率(Breslow test=7.05, P=0.0078 ) 并且腹水复发的更低的概率(51% 对 94% , P<0.0001 ) 。长期的白朊注入导致了 16 瞬间的幸存的吝啬的增加。结论:在第一发作的腹水以后的长期的白朊管理显著地改进病人的幸存并且减少腹水复发的风险。 | Roberto Giulio Romanelli Giorgio La Villa Giuseppe Barletta Francesco Vizzutti Fabio Lanini Umberto Arena Vieri Boddi Roberto Tarquini Pietro Pantaleo Paolo Gentilini Giacomo Laffi | 2006 | World Journal of Gastroenterology2006，12，9： | 22 |
| 2 | An eighteen-month follow-up study on the effects of Intravitreal Dexamethasone Implant in diabetic macular edema refractory to anti-VEGF therapy显示文摘AIM: To evaluate the long-term efficacy and safety of dexamethasone implants in subjects affected by diabetic macular edema(DME) resistant to anti-vascular endothelial growth factor(VEGF) therapy.METHODS: Thirty-two DME patients were enrolled.A700 microgram slow release Intravitreal Dexamethasone Implant(Ozurdex~) was placed in the vitreous cavity.All patients were followed for 18 mo.Best-corrected visual acuity(BCVA) measured with Early Treatment Diabetic Retinopathy Study(ETDRS) and central macular thickness(CMT) exams were carried out at baseline(T0)and after 1(T1),3(T3),4(T4),6(T6),9(T9),12(T12),15(T15),and 18mo(T18) post injection. RESULTS: Repeated measures ANOVA showed an effect of treatment on ETDRS(P<0.0001).Post hoc analyses revealed that ETDRS values were significantly increased at T1,T3,T4,T9,and T15(P <0.001) as compared to baseline value(T0).At T6,T12,and T18,ETDRS values were still statistically higher than baseline(P<0.001 vs T0).However,at these time points,we observed a trend to return to baseline conditions.ANOVA also showed an effect of treatment(P <0.0001).CMT decreased significantly at T1,T3,T4,T9,and T15(P<0.001).At T6(P<0.01),T12 and T18(P<0.001) CMT was also significantly lower than T0 although a trend to return to the baseline conditions was also observed.CONCLUSION: Our findings demonstrate that Intravitreal Dexamethasone Implant is a good option to improveBCVA and CMT in DME patients resistant to anti-VEGF therapy.Our data also show that the use of drugs administered directly into the vitreous allows achieving appropriate and long-lasting concentration at the site of disease without systemic side effects. | Fernanda Pacella Maria Rosaria Romano Paolo Turchetti Giovanna Tarquini Anna Carnovale Antonella Mollicone Alessandra Mastromatteo Elena Pacella | 2016 | International Journal of Ophthalmology(English edition)2016，9，10： | 5 |
| 3 | Hepato-splenic lymphoma:a rare entity mimicking acute hepatitis:A case report显示文摘We reported a case of non-Hodgkin's lymphoma where liver involvement was the predominant clinical manifestation. A 27-year old man presented wiht markedly elevated serum aspartate aminotrasferase, alanine aminotransferase and lactate dehydrogenase, reduced prothrombin activity, thrombocytopenic purpura and hepato-splenomegaly without adenopathy. Viral, toxic,autoimmune and metabolic liver diseases were excluded.Bone marrow biopsy showed an intracapillary infiltration of T-lymphocytes with no evidence of lipid storage disease.Because of a progressive spleen enlargement, splenectomy was performed. Histological examination showed lymphomatous intrasinuses invasion of the spleen.Immunohistochemical investigation revealed the T phenotype of the neoplastic cells: CD45+, CD45RO+,CD3+, CD4-, CD8-, TIA1-. About 50 % of the lymphoid cells expressed CD56 antigen. The diagnosis of hepatosplenic T cell lymphoma was done. The patient was treated with chemotherapy, which induced a complete remission. Eighteen months later, he had a first relapse with increased aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase,thrombocytopenic purpura and blast in the peripheral blood.In spite of autologous bone marrow transplantation, he died twenty months after the diagnosis. Even in the absence of a mass lesion or lymphoadenopathy, hepatosplenic Tcell lymphoma should be considered in the differential diagnosis of a patient whose clinical course is atypical for acute hepatic dysfunction. | Federico Perfetto Roberto Tarquini Francesco Mancuso Simonetta di Lollo Silvia Tozzini Giampiero Bellesi Giacomo Laffi | 2003 | World Journal of Gastroenterology2003，9，6： | 2 |
| 4 | Serum beta-endorphinincrease after intravenous histamine treatment of chronic dailyheadache显示文摘 | Anselmi B Tarquini R Panconesi A et a1 | 1997 | Recenti ProgMed1997，88，78： | 1 |
| 5 | MAGE-A and NY-ESO-1 expression in cervical cancer: Prognostic factors and effects of chemotherapy显示文摘 | Chiara Napoletano Filippo Bellati Elisabetta Tarquini Federica Tomao Federica Taurino Giulio Spagnoli Aurelia Rughetti Ludovico Muzii Marianna Nuti Pierluigi Benedetti Panici | 2008 | American Journal of Obstetrics and Gynecology2008，，1： | 1 |
| 6 | Spontaneous uterine rupture during corneal ectopic pregnancy after recent homolateral salpingectomy 显示文摘 | Galati GM Santomarco N Tarquini M | 2013 | It J Gynaecol Obstet2013，25，3： | 1 |
| 7 | Adiponectin and the cardiovascular system:from risk to disease显示文摘 | Tarquini R Lazzeri C Laffi G | 2007 | Intern Emerg Med2007，2，3： | 1 |
| 8 | The prognostic role of Gamma-glutamyltransferase activity in non-diabetic ST- elevation Myocardial infarction显示文摘 | Lazzeri C Valente S Tarquini R | 2011 | Intern Emerg Med2011，6，3： | 1 |
| 9 | Evidence of bone mass and body fat distribution relationship in postmenopausal obese women显示文摘 | Tarquini B Navari N Perfetto F | 1997 | Arch Geronol Geriatr1997，24，： | 1 |
| 10 | Adiponectin and the cardio- vascular system:from risk to disease显示文摘 | Tarquini R Lazzeri C Laffi G | 2009 | Intern Emerg Med2009，2，3： | 1 |
| 11 | The diabetic cardiomyopathy 显示文摘 | Tarquini R Lazzeri C Pala L | 2011 | Acta Diabetol2011，48，3： | 1 |
| 12 | Corrosion of Residential Aboveground Heating Oil Tanks: An Overview显示文摘 | Marina Banuta Isabelle Tarquini | 2010 | Journal of Failure Analysis and Prevention2010，，2： | 1 |
| 13 | Expression of the CDK inhibitor p27kipl and oxidativeDNA damage in non-neoplastic and neoplastic vulvar epithelial lesions显示文摘 | Zannoni GF Faraglia B Tarquini E | 2006 | Mod Pathol2006，19，4： | 1 |
| 14 | The diabetic cardio- myopathy 显示文摘 | Tarquini R Lazzeri C Pala L | 2011 | Acta Diabetol2011，48，3： | 1 |
| 15 | Persistent vegetative state : an ethical reappraisal显示文摘 | Tarquini D Congedo M Formagho F | 2012 | Neurol Sci2012，33，3： | 1 |
| 16 | Prevention of non-steroidal antiinflammatory drug-induced gastrointestinal mueosal injury: risk factors for serious complications显示文摘 | Koch M Dezi A Tarquini M | 2000 | Dig Live Dis2000，32，2： | 1 |
| 17 | Corrosion of residential aboveground heat ing oil tanks: An overview显示文摘 | Banuta M Tarquini I | 2010 | Journal of Failure Analysis and Prevention2010，10，1： | 1 |
| 18 | The diabetic cardiomyopathy 显示文摘 | Tarquini R Lazzeri C Pala L | 2011 | Acta Diabetol2011，48，3： | 1 |
| 19 | Solar linear Fresnel collector using molten nitrates as heat transfer fluid 显示文摘 | Grena R Tarquini P | 2011 | Energy2011，，36： | 1 |
| 20 | Infliximab for Severe Recurrent Crohn’s Disease Presenting With Massive Gastrointestinal Hemorrhage显示文摘 | Claudio Papi Loredana Gili Maurizio Tarquini Giorgio Antonelli Lucio Capurso | 2003 | Journal of Clinical Gastroenterology2003，，3： | 1 |
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