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| 1 | Effect of IOP based infusion system with and without balanced phaco tip on cumulative dissipated energy and estimated fluid usage in comparison to gravity fed infusion in torsional phacoemulsification显示文摘Background:To evaluate the effect of three different combinations of tip designs and infusion systems in torsional phacoemulsification(INFINITI and CENTURION)in patients with cataract.According to the manufacturer,two unique improvements in the Centurion are:active fluid dynamic management system and use of an intrepid balanced tip.The study specifically aimed to evaluate the beneficial effects,if any,of change in tip design and infusion system individually and in combination on both per-operative parameters as well as endothelial health over 6 months.Methods:One hundred and twenty six consenting patients of grade 4.0-6.9 senile cataract were randomized into three groups for phacoemulsification:Group A(n=42):Gravity fed infusion system and 45° Kelman miniflared ABS phaco tip;Group B(n=42):intraocular pressure(IOP)based infusion system and 45° Kelman miniflared ABS phaco tip;Group C(n=42):IOP based infusion system and 45° Intrepid balanced phaco tip.The cumulative dissipated energy(CDE),estimated fluid usage(EFU)and total aspiration time(TAT)were compared peroperatively.The endothelial parameters were followed up postoperatively for six months.Results:The three arms were matched for age(p=0.525),gender(p=0.96)and grade of cataract(p=0.177).Group C was associated with significant reductions in CDE(p=0.001),EFU(p<0.0005)as well as TAT(p=0.001)in comparison to the other groups.All three groups had comparable baseline endothelial cell density(p=0.876)and central corneal thickness(p=0.561).On post-operative evaluation,although all groups were comparable till 3 months,by 6 months,the percentage losses in endothelial cell density were significantly lower in group C as compared to the other groups.Conclusions:Use of an IOP based phacoemulsification system in association with use of the Intrepid balanced tip reduces the CDE,EFU and TAT in comparison to a gravity fed system with a mini flared tip or IOP based system with a mini flared tip while also providing better endothelial preservation thus favouring the use of an IOP fed system with a balanced tip. | Praveen K.Malik Taru Dewan Arun Kr Patidar Ekta Sain | 2017 | Eye and Vision2017，4，1： | 11 |
| 2 | 芬兰职业教育的教师教育显示文摘教育在芬兰社会中具有重要作用。如果没有人力资本的重大贡献,特别是教育和培训,对于一个20世纪60年代还是贫穷的农业国家而言,很难建设成为一个具有强大经济竞争力和社会凝聚力的福利国家。最近的国际学生成绩比较研究(PISA,2000年和2003年)显示,芬兰学生在阅读、科学和数学素养方面的表现特别好。更重要的是, | 吴全全 Ritta Metsaenen Taru Dorra | 2010 | 中国职业技术教育2010，26，28： | 8 |
| 3 | Cost-utility of molecular adsorbent recirculating system treatment in acute liver failure显示文摘AIM:To determine the short-term cost-utility of mo-lecular adsorbent recirculating system(MARS) treatment in acute liver failure(ALF).METHODS:A controlled retrospective study was conducted with 90 ALF patients treated with MARS from 2001 to 2005.Comparisons were made with a historical control group of 17 ALF patients treated from 2000 to 2001 in the same intensive care unit(ICU) specializing in liver diseases.The 3-year outcomes and number of liver transplantations were recorded.All direct liver disease-related medical expenses from 6 mo before to 3 years after ICU treatment were determined for 31 MARS patients and 16 control patients.The health-related quality of life(HRQoL) before MARS treatment was estimated by a panel of ICU doctors and after MARS using a mailed 15D(15-dimensional generic healthrelated quality of life instrument) questionnaire.The HRQoL,cost,and survival data were combined and the incremental cost/quality-adjusted life years(QALYs) was calculated.RESULTS:In surviving ALF patients,the health-related quality of life after treatmeant was generally high and comparable to the age-and gender-matched general Finnish population.Compared to the controls,the average cost per QALY was considerably lower in the MARS group(64 732€ vs 133 858€) within a timeframe of 3.5 years.The incremental cost of standard medical treatment alone compared to MARS was 10 928€,and the incremental number of QALYs gained by MARS was 0.66.CONCLUSION:MARS treatment combined with standard medical treatment for ALF in an ICU setting is more cost-effective than standard medical treatment alone. | Taru Kantola Suvi Mklin Anna-Maria Koivusalo Pirjo Rsnen Anne Rissanen Risto Roine Harri Sintonen Krister Hckerstedt Helena Isoniemi | 2010 | World Journal of Gastroenterology2010，16，18： | 3 |
| 4 | Survival predictors in patients treated with a molecular adsorbent recirculating system显示文摘AIM:To identify prognostic factors for survival in patients with liver failure treated with a molecular adsorbent recirculating system(MARS). METHODS:MARS is a liver-assisting device that has been used in the treatment of liver failure to enable native liver recovery,and as a bridge to liver transplantation(LTX).We analyzed the 1-year outcomes of 188 patients treated with MARS,from 2001 to 2007, in an intensive care unit specializing in liver disease. Demographic,clinical and laboratory parameters were recorded before and after each treatment.One-year survival and the number of LTXs were recorded.Logistic regression analysis was performed to determine factors predicting survival. RESULTS:The study included 113 patients with acute liver failure(ALF),62 with acute-on-chronic liver failure(AOCLF),11 with graft failure(GF),and six with miscellaneous liver failure.LTX was performed for 29% of patients with ALF,18% with AOCLF and 55%with GF.The overall 1-year survival rate was 74% for ALF,27% for AOCLF,and 73% for GF.The poorest survival rate,6%,was noted in non-transplanted patients with alcohol-related AOCLF and cirrhosis,whereas,patients with enlarged and steatotic liver had 55% survival.The etiology of liver failure was the most important predictor of survival(P<0.0001).Other prognostic factors were encephalopathy(P=0.001)in paracetamol-related ALF, coagulation factors(P=0.049)and encephalopathy(P=0.064)in non-paracetamol-related toxic ALF,and alanine aminotransferase(P=0.013)and factor V levels(P =0.022)in ALF of unknown etiology. CONCLUSION:The etiology of liver disease was the most important prognostic factor.MARS treatment appears to be ineffective in AOCLF with end-stage cirrhosis without an LTX option. | Taru Kantola Anna-Maria Koivusalo Satu Parmanen Krister Hckerstedt Helena Isoniemi | 2009 | World Journal of Gastroenterology2009，15，24： | 3 |
| 5 | Regulatory T cells and TH1/3M2 cytokines as immunodiagnosis keys in systemic autoiranune diseses显示文摘 | Ursaciuc C Surcel M Cio taru D | 2010 | Roum Arch Microbiol Immunol2010，69，2： | 1 |
| 6 | Metabolomic changes in fatty liver can be modified by dietary protein and calcium during energy restriction显示文摘AIM: To characterise the effect of energy restriction (ER) on liver lipid and primary metabolite profile by using metabolomic approach. We also investigated whether the effect of energy restriction can be further enhanced by modif ication of dietary protein source and calcium. METHODS: Liver metabolomic profile of lean and obese C57Bl/6J mice (n = 10/group) were compared with two groups of weight-reduced mice. ER was performed on control diet and whey protein-based high-calcium diet (whey + Ca). The metabolomicanalyses were performed using the UPLC/MS based lipidomic platform and the HPLC/MS/MS based primary metabolite platform. RESULTS: ER on both diets significantly reduced hepatic lipid accumulation and lipid droplet size, while only whey + Ca diet significantly decreased blood glucose (P < 0.001) and serum insulin (P < 0.01). In hepatic lipid species the biggest reduction was in the level of triacylglycerols and ceramides while the level of cholesterol esters was significantly increased during ER. Interestingly, diacylglycerol to phospholipid ratio, an indicator of relative amount of diabetogenic diglyceride species, was increased in the control ER group, but decreased in the whey + Ca ER group (P < 0.001, vs obese). ER on whey + Ca diet also totally reversed the obesity induced increase in the relative level of lipotoxic ceramides (P < 0.001, vs obese; P > 0.05, vs lean). These changes were accompanied with up-regulated TCA cycle and pentose phosphate pathway metabolites. CONCLUSION: ER-induced changes on hepatic metabolomic profile can be significantly affected by dietary protein source. The therapeutic potential of whey protein and calcium should be further studied. | Taru K Pilvi Tuulikki Seppnen-Laakso Helena Simolin Piet Finckenberg Anne Huotari Karl-Heinz Herzig Riitta Korpela Matej Orei Eero M Mervaala | 2008 | World Journal of Gastroenterology2008，14，28： | 1 |
| 7 | Coupling in Dual-core Photonic Band Gap Fibers: Theory and Experiment 显示文摘 | WANG Z TARU T BIRKS T A | 2007 | Opt Express2007，15，： | 1 |
| 8 | Structure-based discovery of the novel antiviral properties of naproxen against the nueleoprotein of influenza A virus 显示文摘 | Lejal N Tarus B Bouguyon E | 2013 | Antimicrob Agents Chemother2013，57，5： | 1 |
| 9 | De- sign and Fabrication of Ultra-Low Crosstalk and Low-Loss Multi-Core Fiber显示文摘 | HAYASHI T TARU T SHIMAKAWA O | 2011 | Optics Express2011，19，16： | 1 |
| 10 | Value co-crea- tion in solution networks显示文摘 | ELINA JAAKKOLA TARU HAKANEN | 2012 | Industrial Marketing Manage- ment2012，7，17： | 1 |
| 11 | Localization and Expression of Follicle-Stimulating Hormone Receptor Oene in Buffalo (Bubalus bubalis) Pre-Antral Follicles显示文摘 | Taru Sharma G Dubey P K Sai Kumar G | 2011 | Reproduction in domestic animals2011，46，1： | 1 |
| 12 | Board demographic diversity, firm performance and strategic change: A test of moderation显示文摘 | Tarus D K Aime F | 2014 | Management Research Review2014，37，12： | 1 |
| 13 | Expression and characterization of the Drosophila X11-like/Mint protein during neural development显示文摘 | Hase M Yagi Y Taru H | 2002 | J Neurochem2002，81，6： | 1 |
| 14 | Impact of educational intervention on implementation of tobacco counselling among oral health professionals: a cluster‐randomized community trial显示文摘 | Masamitsu Amemori Jorma Virtanen Tellervo Korhonen Taru H. Kinnunen Heikki Murtomaa | 2012 | Community Dent Oral Epidemiol2012，，2： | 1 |
| 15 | Ethical Organisational Culture as a Context for Managers'Personal Work Goals显示文摘 | Mari Huhtala Taru Feldt Katriina Hyvo nen Saija Mauno | 2013 | Journal of Business Ethics2013，114，2： | 1 |
| 16 | Sense of coherence and five-factor approach to personality:Conceptual relationships显示文摘 | Taru Feldt Riitt-Leena Metsapelt Ulla Kinnunen | | 0，，03： | 1 |
| 17 | Charac- terization of Crosstalk in Ultra-Low-Crosstalk Multi- Core Fiber显示文摘 | HAYASHI T TARU T SHIMAKAWA O et el | 2012 | Journal of Lightwave Technology2012，30，4： | 1 |
| 18 | Effects of enzymes in fiber-enriched baking显示文摘 | Taru Laurikainen Helena H?rk?nen Karin Autio Kaisa Poutanen | 1998 | Sci Food Agric1998，76，： | 1 |
| 19 | In vitro development of reconstructed goat oocytes after somatic cell nuclear transfer with fetal fibroblast cells显示文摘 | DAS S K MAJUMDAR A C TARU SHARMA G | 2003 | Small Ruminant Research2003，48，3： | 1 |
| 20 | 显示文摘 | Taru K M Michael S F David R W | 2000 | Chem Mater2000，，12： | 1 |
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