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| 1 | 应激对风险和社会决策的影响显示文摘应激是有机体在受到真实或者潜在的威胁刺激时所表现出来的全身性非特异性反应,伴随着紧张和焦虑的心理体验,交感神经系统的兴奋,糖皮质激素分泌的增多以及脑干-边缘系统-前额叶神经环路的改变。应激对个体在风险决策行为中的风险寻求和风险回避倾向,社会决策行为中的利己和利他倾向都会产生重要影响。策略使用异常、习惯化和自动化反应增强、反馈学习过程以及奖惩敏感性的改变是应激影响决策行为的认知基础;应激激素的分泌,及杏仁核、前额叶等在决策过程发挥重要作用的脑区活动的改变则为应激作用于决策行为的神经基础。未来研究应重点关注:应激的个体差异与应激对决策影响效应多样性的关系;综合多种指标对应激进行测量;考察应激的时序效应;揭示个体的最佳应激水平;加强对慢性应激影响决策以及应激对决策影响效应可逆性的研究;揭示应激影响决策的神经机制。 | 杨群 李煜 孙得琳 Tatia M.C.LEE | 2016 | 心理科学进展2016，24，6： | 10 |
| 2 | Gender Role,But Not Sex,Shapes Humans’Susceptibility to Emotion显示文摘It is unknown whether the famous sex-related difference in emotion processing is accounted for by biological sex,gender role,or their interaction.To clarify the issue,in Study 1 we recorded event-related potentials in response to negative and positive images of diverse intensities when 47 masculine(26 males)and 47 feminine(22 males)subjects performed a non-emotional task.The occipital P1 and N1 amplitudes were larger in women than in men,while feminine subjects showed larger N1 amplitudes than masculine subjects,regardless of sex.Moreover,feminine subjects showed enhanced frontocentral N2(210–270 ms)amplitudes for highly and mildly negative than for neutral stimuli,while masculine subjects showed an emotion effect only for highly negative stimuli.The feminine-specific effect for mildly negative stimuli was positively correlated to the feminine score,and this correlation was located to the anterior cingulate and the superior and medial frontal gyri.Furthermore,feminine but not masculine subjects showed enhanced parietal P3(330–560 ms)amplitudes for highly and mildly positive than for neutral stimuli,an effect positively related to the feminine score and localized to the precuneus,posterior cingulate,and superior temporal gyrus.Machine learning analyses verified that single-trial N2 and P3 amplitudes of feminine subjects reliably discriminated the intensity of negative and positive stimuli,respectively.For ecological considerations,in Study 2 we used an observational approach(n=300)and confirmed that feminine gender role,rather than biological sex,predicted individual differences in daily experience of emotion-related psychopathological symptoms.These findings provide solid evidence for the critical impact of gender role rather than sex on emotional susceptibility. | Jiajin Yuan Hong Li Quanshan Long Jiemin Yang Tatia M.C.Lee Dandan Zhang | 2021 | Neuroscience Bulletin2021，37，2： | 4 |
| 3 | 前额叶损伤患者的风险决策认知障碍显示文摘目的探讨前额叶眶部(OBF)和背外侧(DLF)损伤对风险决策认知加工的影响,验证OBF参与风险决策认知加工过程的假说。方法OBF损伤患者21例,DLF损伤患者19例以及健康对照组(HC)40名,采用风险决策任务,比较各组执行风险决策的能力。结果组内与奖赏后相比,惩罚后HC组的风险选择频率显著下降(分别为0.68±0.16和0.54±0.23,P<0.01),表现为惩罚后风险选择的抑制效应;DLF损伤组患者在惩罚后的风险选择频率亦有显著下降(分别为0.72±0.22和0.63±0.25,P<0.05);而OBF损伤组患者在惩罚后风险选择的抑制效应消失(分别为0.79±0.19和0.82±0.18,P>0.05)。与HC组比较,OBF损伤组患者在奖赏后和惩罚后的风险选择频率均显著升高(奖赏后分别为0.68±0.16和0.79±0.19,惩罚后分别为0.54±0.23和0.82±0.18;P<0.05),而DLF损伤组患者无显著变化(奖赏后分别为0.68±0.16和0.72±0.22,惩罚后分别为0.54±0.23和0.63±0.25;P>0.05)。结论OBF和DLF在人类的风险决策认知加工过程存在分离。OBF损伤后的患者追求高奖赏,惩罚后风险选择的抑制效应消失,而DLF损伤组患者的风险决策能力正常。OBF可能参与了奖赏/惩罚认知加工过程,是风险决策认知加工和处理的重要脑区。 | 席春华 傅先明 汪凯 牛朝诗 Lee Tatia MC 孟玉 朱春燕 杜静 | 2006 | 中华医学杂志2006，86，45： | 3 |
| 4 | Roles of paroxetine and corticosterone on adult mammalian ciliary body cell proliferation显示文摘背景在成年哺乳动物的视网膜的神经发生通常被废除,并且这显示再生 capacity.Despite 的视网膜缺乏这,有在保留学习在调查二药,皮质脂酮和 paroxetine 的效果瞄准了的在场的神经原的 potential.The 的睫的上皮的nestin积极的房间的一张小人口,在老鼠是的睫的 body.Methods 成年人 Sprague-Dawley 的房间增长上给车辆,皮质脂酮, paroxetine ,或两个 | WANG Hua LAU Benson WM YAU Suk-yu LI Suk-yee LEUNG Nelson WANG Ning-li TANG Siu-wa LEE Tatia MC SO Kwok-fai | 2010 | Chinese Medical Journal2010，，10： | 2 |
| 5 | Thirsty heroin addicts show different fMRI activations when exposed to water-related and drug-related cues显示文摘 | Zhuangwei Xiao Tatia Lee John X Zhang | 2006 | Drug Alcohol Depend2006，83，： | 1 |
| 6 | Thirsty heroin addicts show different fMIRI activations when exposed to water-related and drug-related cues显示文摘 | Zhuang WX Tatia L John XZ | 2006 | Drug Alcohol Depend2006，83，： | 1 |
| 7 | Lutein Is Stable in Strawberry Yogurt and Does Not Affect its Characteristics显示文摘 | Kayanush J.Aryana Hannah T.Barnes Tatia K.Emmick PaulaMcGrew BarryMoser | 2006 | Journal of Food Science2006，，6： | 1 |
| 8 | Could mood state affect risk-taking decisions?显示文摘 | Kenneth S.L Yuen Tatia M.C Lee | 2002 | Journal of Affective Disorders2002，，1： | 1 |
| 9 | Semantics and Knowledge Grids : Building the Next - Generation Grid 显示文摘 | Cannataro M Tatia D | 2004 | IEEE Intelligent Systems2004，19，1： | 1 |
| 10 | Possible Retrogenesis Observed with Fiber Tracking: An Anteroposterior Pattern of White Matter Disintegrity in Normal Aging and Alzheimer’s Disease显示文摘 | Junling Gao Raymond Tak-Fai Cheung Tatia M.C. Lee Leung-Wing Chu Ying-Shing Chan Henry Ka-Fung Mak John X. Zhang Deqiang Qiu Germaine Fung Charlton Cheung | 2011 | Journal of Alzheimer’s Disease2011，，1： | 1 |
| 11 | Neural activities underlying environmentaland personal risk identification tasks显示文摘 | Qin Jungang Lee Tatia M C Wang Fan Mao Lihua Han Shihui | 2009 | NeuroscienceLetters2009，455，2： | 1 |
| 12 | Translation and validation of the standard Chinese version of PDQ‐39: A quality‐of‐life measure for patients with Parkinson’s disease显示文摘 | Kin‐LunTsang IrisChi Shu‐LeongHo Vivian WeiqunLou Tatia M.C.Lee Leung‐WingChu | 2002 | Mov Disord2002，，5： | 1 |
| 13 | BIS-guided AnesthesiaDecreases Postoperative Delirium and Cognitive Decline显示文摘 | Matthew Chan Benny Cheng Tatia Lee | 2013 | J NeuroAnesth2013，25，1： | 1 |
| 14 | Effect on human attention of exposure to the electromagnetic field emitted by mobile phones显示文摘 | Tatia M.Tsang | | 0，，： | 1 |
| 15 | Transforming Role of Rehabilitation Psychologists: New Paradigm Challenges, and Directions显示文摘Rehabilitation is an integrated program of interventions that support individuals with disabilities and chronic health conditions to attain 'personally fulfilling, socially meaningful, | June LY Tang Tatia MC Lee | 2010 | 中国康复医学杂志2010，25，4： | 0 |
| 16 | Low dose of corticosterone treatment with exercise increases hippocampal cell proliferation, and improves cognition显示文摘Intermediate level of stress is beneficial for brain functions, whereas extreme low level or high level of stress is deleterious. We have previously shown that chronic exposure to high doses of corticosterone (CORT) suppressed hippocampal plasticity and physical exercise in terms of running counteracted the detrimental effects of CORT treatment. We aimed to study whether a mild stress, that mimicked by a treatment with low CORT dose, improved hippocampal plasticity in terms of hippocampal cell proliferation and dendritic remodeling, and to examine whether running with CORT treatment showed an additive effect on improving hippocampal plasticity. The rats were treated with 20 mg/kg CORT for 14 days with or without running, followed by Morris water maze test or forced swim test. The hippocampal proliferating cells was labeled by intraperitoneal injection of 5-bromo-2'-deoxyuridine. The dendritic morphology was analyzed using Golgi staining method. Treatment with 20 mg/kg CORT alone yielded a higher number of hippocampal cell proliferation and significantly increased dendritic branching compared to vehicle-treated non-runners, but had no behavioral effects. In contrast, CORT treatment with running showed an additive increase in hippocampal cell proliferation and dendritic remodeling that was associated with improved spatial learning and decreased depression-like behavior; however, there was no additive improvement in behavior compared to vehicle-treated runners. These findings suggest that mild stress does not always cause detrimental effect on the brain, and combining mild stress with running could promote hippocampal plasticity via inducing cell proliferation and dendritic remodeling. | Suk-Yu Yau Jada Chia-Di Lee Benson Wui-Man Lau Tatia M.C. Lee Yick-Pang Ching Siu-Wa Tang Kwok-Fai So | 2011 | Neural Regeneration Research2011，6，34： | 0 |
| 17 | The inter-relationships of the neural basis of rumination and inhibitory control:neuroimaging-based meta-analyses显示文摘Rumination,as a clinical manifestation and pathogenic factor of depression,has long been the focus of psycho-logical research regarding its causes and ameliorating approaches.Behavioral studies have shown that rumina-tion is related to inhibitory control deficits,which provides ideas for reducing it.However,the neural relationship between them has not been clearly discussed.In this study,we first used multi-level kernel density analysis to conduct two meta-analyses of published functional magnetic resonance imaging studies:one was rumination comprising 17 studies with 180 foci,and the other was inhibitory control comprising 205 studies with 3791 foci.Conjunction analysis was then performed to explore the common brain regions and further decode them through Neurosynth to confirm the cognitive specificity.Results showed that rumination was mainly related to the default mode network(DMN),while inhibitory control was associated with the frontoparietal network(FPN).In addition,the common activation areas were mainly concentrated in the bilateral precuneus,right supe-rior frontal gyrus,bilateral median cingulate,paracingulate gyri,and the left triangular part of inferior frontal gyrus(IFG).Decoding results also revealed they were involved in inhibition,memory retrieval,and self-related processes.Our findings support that rumination is associated with inhibitory control and can be explained neu-rologically by an antagonistic relationship between the DMN and FPN.In sum,inhibitory control may be related to rumination via inhibiting task-unrelated attention and controlling self-related processing.This research will help us understand and predict rumination from the perspective of inhibitory control and reduce rumination through behavioral training of inhibitory control or the application of neuromodulation techniques to common activation regions. | Xiaoqi Song Jixin Long Chanyu Wang Ruibin Zhang Tatia M.C.Lee | 2022 | Psychoradiology2022，2，1： | 0 |
| 18 | 香港脑损伤患者的出院后服务(英文)显示文摘目的:建立针对脑损伤患者及其看护者的可负担、易获取的出院后电话跟进服务,并为发展区域内有成本效益的连续监护体制提供实证基础。方法:本研究从香港大学玛丽医院脑外科招募35名成年脑损伤患者和26名看护者。参与者在出院后第4周和第12周各接受一次结构化的电话访谈。有调整能力不足风险的患者与看护者将被送交进一步的医疗咨询或心理干预。患者的生理和认知功能,以及患者与看护者的情感功能、知觉到的社会支持和对当前所提供的服务的满意程度都被列入调查。结果:大部分患者报告他们的生理状况有明显改善。相当多的患者在出院后经历过认知困难并报告所接受到的社会心理支持不足。大多数看护者报告在看护期间健康、情感功能和社会生活受损。患者与看护者都对服务表示满意,看护者的满意程度更高。结论:脑损伤患者及其看护者都受益于出院后电话跟进服务。两者都同意该项服务有助于识别有调整能力不足风险的个体,并提供及时的建议和情感支持。看护工作会明显损害看护者的生理、情感功能和社会生活,提示需要为他们提供关于看护技巧、生活调整和压力管理的意见与建议。 | Helena MK Tam Tatia MC Lee | 2011 | 中国康复医学杂志2011，26，12： | 0 |
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