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| 1 | Distribution of the P2X2 receptor and chemical coding in ileal enteric neurons of obese male mice(ob/ob)显示文摘AIM:To investigate the colocalization,density and profile of neuronal areas of enteric neurons in the ileum of male obese mice.METHODS:The small intestinal samples of male mice in an obese group(OG)(C57BL/6J ob/ob)and a control group(CG)(+/+)were used.The tissues were analyzed using a double immunostaining technique for immunoreactivity(ir)of the P2X2 receptor,nitric oxide synthase(NOS),choline acetyl transferase(ChAT)and calretinin(Calr).Also,we investigated the density and profile of neuronal areas of the NOS-,ChAT-and Calrir neurons in the myenteric plexus.Myenteric neurons were labeled using an NADH-diaphorase histochemical staining method.RESULTS:The analysis demonstrated that the P2X2receptor was expressed in the cytoplasm and in the nuclear and cytoplasmic membranes only in the CG.Neuronal density values(neuron/cm2)decreased 31%(CG:6579±837;OG:4556±407)and 16.5%(CG:7796±528;OG:6513±610)in the NOS-ir and calretininir neurons in the OG,respectively(P<0.05).Density of ChAT-ir(CG:6200±310;OG:8125±749)neurons significantly increased 31%in the OG(P<0.05).Neuron size studies demonstrated that NOS,ChAT,and Calr-ir neurons did not differ significantly between the CG and OG groups.The examination of NADH-diaphorase-positive myenteric neurons revealed an overall similarity between the OG and CG.CONCLUSION:Obesity may exert its effects by promoting a decrease in P2X2 receptor expression and modifications in the density of the NOS-ir,ChAT-ir and CalR-ir myenteric neurons. | Márcia Sanae Mizuno Amanda Rabello Crisma Primavera Borelli Bárbara Tavares Schfer Mariana Póvoa Silveira Patricia Castelucci | 2014 | World Journal of Gastroenterology2014，20，38： | 3 |
| 2 | Clinical and hematological signs associated with dogs naturally infected by Hepatozoon sp. and with other hematozoa: A retrospective study in Uberlandia, Minas Gerais, Brazil显示文摘 | Antonio Vicente Mundim Iara Aparecida de Morais Marcelo Tavares Márcia Cristina Cury Maria José Santos Mundim | 2008 | Veterinary Parasitology2008，，1： | 2 |
| 3 | Affine equivalence in the AES round function显示文摘 | Youssef A M Tavares S E | 2005 | Discrete Applied Mathematics2005，148，2： | 1 |
| 4 | Pressor effects of electrical stimulation of medial prefrontal cortex in unanesthetized rats显示文摘 | TAVARES R F ANTUNES-RODRIGUES J DE AGUIAR CORREA F M | 2004 | Journal of Neuroscience Research2004，77，4： | 1 |
| 5 | Insulin- stimulated fatty acid synthase gene expression does not require increased sterol response element binding protein 1 transcription in primary adipoeytes显示文摘 | PALMER D G RUTTER G A TAVARE J M | 2002 | Biochem Bio- ph Res Commun2002，291，3： | 1 |
| 6 | Leptin effect on RANKL and OPG expression in MC3T3-E1 osteoblasts 显示文摘 | Lamghari M Tavares L Camboa N Barbosa M A | 2006 | J Cell Biochem2006，98，5： | 1 |
| 7 | Milk - coagulating enzymes of tuna fish waste as a rennet substitute 显示文摘 | Tavares J F Baptista J A Marcone M F | 1997 | International Journal of Food Sciences and Nutrition1997，48，3： | 1 |
| 8 | The effect of light quality on leaf production and development of in vitro - cultured plants of Alternanthera brasiliana Kuntze 显示文摘 | MACED A F LEAL-COSTA M V TAVARES E S | 2011 | Environ Exp Bot2011，70，1： | 1 |
| 9 | Video endoscopic inguinal lymphadenectomy (VEIL): Minimally invasive resection of inguinal lymph nodes 显示文摘 | Tobias-Machado M Tavares A Molina WR Jr | 2006 | Int Braz J Urel2006，32，3： | 1 |
| 10 | Immobilization of commercial laccase on spent grain显示文摘 | da Silva A M Tavare A P M Rocha C M R | 2012 | Process Biochem2012，479，7： | 1 |
| 11 | Increased resistance to systemic candidiasis in athymic or interleukin-10-depleted mice显示文摘 | Tavares D Ferreira P Arala-Chaves M | 2000 | J Infect Dis2000，182，： | 1 |
| 12 | Determination of the centesimal composition and characterization of flours from fruit seeds显示文摘 | Lima B N B Lima F F Tavares M I B | 2014 | Food Chemistry2014，151，4： | 1 |
| 13 | Interstitial cells of Cajal in chagasic megaesophagus 显示文摘 | de Lima MA Cabrine - Santos M Tavares MG | 2008 | Ann Diagn Pathol2008，12，4： | 1 |
| 14 | A review of algorithms for medical image segmentation and their applications to the female pelvic cavity 显示文摘 | Ma Zhen Tavares J M R S Jorge R N | 2010 | Computer Methods in Biomechanies and Biomedical Engineering2010，13，2： | 1 |
| 15 | Effect of experimental conditions on cogasification of coal,biomass and plastics wastes with air/steam mixtures in a fluidized-bed system显示文摘 | PINTO F FRANCO C ANDRE R TAVARES C DIAS M GULYURTLU I CABRITA I | 2003 | Fuel2003，82，1517： | 1 |
| 16 | Can video endoscopic inguinal lymphadenectomy achieve a lower morbidity than open lymph node dissection in penile cancer patients? 显示文摘 | Tobias-Machado M Tavares A Silva MN | 2008 | J Endourol2008，22，8： | 1 |
| 17 | The σ phase formation in annealed UNS S31803 duplex stainless steel: Texture aspects显示文摘 | Souza C M Abreu H F G Tavares S S M | 2008 | Materials Characterization2008，59，9： | 1 |
| 18 | Optimizing the separation of food dyes by capillary electrophoresis显示文摘 | Jager A V Tonin F G Tavares M F M | 2005 | J Sep Sci2005，28，910： | 1 |
| 19 | Magnetic Properties and α' Martensite Quantification in an AISI 301LN Stainless Steel Deformed by Cold Rolling 显示文摘 | Tavares S S M Neto J M Silva M R | 2008 | Mater Charact2008，59，7： | 1 |
| 20 | Alkaline leaching of zinc from electric arc furnace steel dust显示文摘 | A J B Dutra P R P Paiva L M Tavares | 2006 | Minerals Engineer- ing2006，19，： | 1 |
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