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| 1 | The role of the N-methyl-D-aspartate receptor in the proliferation of adult hippocampal neural stem and precursor cells显示文摘New neurons are continuously generated from resident pools of neural stem and precursor cells(NSPCs)in the adult brain.There are multiple pathways through which adult neurogenesis is regulated,and here we review the role of the N-methyl-D-aspartate receptor(NMDAR)in regulating the proliferation of NSPCs in the adult hippocampus.Hippocampal-dependent learning tasks,enriched environments,running,and activity-dependent synaptic plasticity,all potently up-regulate hippocampal NSPC proliferation.We first consider the requirement of the NMDAR in activity-dependent synaptic plasticity,and the role the induction of synaptic plasticity has in regulating NSPCs and newborn neurons.We address how specific NMDAR agonists and antagonists modulate proliferation,both in vivo and in vitro,and then review the evidence supporting the hypothesis that NMDARs are present on NSPCs.We believe it is important to understand the mechanisms underlying the activation of adult neurogenesis,given the potential that endogenous stem cell populations have for repopulating the hippocampus with functional new neurons.In conditions such as age-related memory decline,neurodegeneration and psychiatric disease,mature neurons are lost or become defective;as such,stimulating adult neurogenesis may provide a therapeutic strategy to overcome these conditions. | TAYLOR Chanel J HE RongQiao BARTLETT Perry F | 2014 | Science China(Life Sciences)2014，57，4： | 6 |
| 2 | The CNS phenotype of X-linked Charcot-Marie-Tooth disease-More than a peripheral problem显示文摘 | Simon EM Marks HE | 2003 | Neurology2003，61，： | 1 |
| 3 | Global microRNA expres?sion profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes显示文摘 | Herrera BM Lockstone HE Taylor JM | 2010 | Diahetologia2010，53，6： | 1 |
| 4 | MicroRNA- 125a is over-expressed in insulin target tissues in a spontaneous rat model of type 2 diabetes 显示文摘 | Herrera BM Lockstone HE Taylor JM | 2009 | Bmc Med Genomics2009，2，1： | 1 |
| 5 | Structure-function analysis of LIV-1,the breast cancer-associated protein that belongs to a new subfamily of zinc transporters显示文摘 | Taylor KM Morgan HE Johnson A | 2003 | Biochem J2003，375，： | 1 |
| 6 | Stoichiometric depolymerization of polyuronides and glycosaminoglycuronans to monosaccharides following reduction of their carbodiimideactivated carboxyl groups 显示文摘 | Taylor RL Conrad HE | 1972 | Biochemistry1972，11，8： | 1 |
| 7 | Prognostic reiability of visual evoked potential of asphyxiated term infants 显示文摘 | Taylor MJ Murphy WJ Wbyte HE | 1992 | Dev Med Child Neurol1992，34，6： | 1 |
| 8 | The emerging role of the LIV-1 subfamily of zinc transporters in breast cancer显示文摘 | Taylor KM Morgan HE Smart K | 2007 | Mol Med2007，13，： | 1 |
| 9 | Global mi- croRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes显示文摘 | Herrera BM Lockstone HE Taylor JM | 2010 | Diabetologia2010，53，： | 1 |
| 10 | MicroRNA-125a is over-expressed in insulin target tissues in a spontaneous rat model of Type 2 Diabetes 显示文摘 | Herrera BM Lockstone HE Taylor JM | 2009 | BMC Med Genomics2009，2，： | 1 |
| 11 | Kyphoplasty- augmented short-segment pedicle screw fixation of traumatic lumbar burst fractures显示文摘 | Acosta FL Jr Aryan HE Taylor WR | 2005 | Neurosurg Focus2005，18，3： | 1 |
| 12 | Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes 显示文摘 | Herrera BM Lockstone HE Taylor JM | 2010 | Diabetologia2010，53，6： | 1 |
| 13 | Multi-objective optimal reactive power flow including voltage security and demand profile classification 显示文摘 | He R Taylor G A Song Y H | 2008 | International journal of Electrical Power and Energy Systems2008，30，5： | 1 |
| 14 | Vascular endothelial growth factor receptor-2:counter-regulation by the transcription factors,TFII-Ⅰ and TFII-IRD1显示文摘 | Jackson TA Taylor HE Sharma D | 2005 | J Biol Chem2005，280，29： | 1 |
| 15 | Global microRNA ex- pression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes显示文摘 | Herrera BM Lockstone HE Taylor JM | 2010 | Diabetologia2010，53，6： | 1 |
| 16 | Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters显示文摘 | Taylor KM Morgan HE Johnson A | 2003 | Biochem J2003，375，： | 1 |
| 17 | Adenoroatoid tumors of the uterus and fallopian tube显示文摘 | Youngs LA Taylor HE | 1967 | Am J Clin Pathol1967，48，： | 1 |
| 18 | Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes显示文摘 | Herrera BM Lockstone HE Taylor JM | 2010 | Diabetologia2010，53，： | 1 |
| 19 | Predictive value of the hemizona assay for pregnancy outcome in patients undergoing controlled ovarian hyperstimulation with intrauterine insemination显示文摘 | Arslan M Morshedi M Ozturk Arslon E Taylor S Kanik A Duran HE Oehninger S | 2006 | Fertil Steril2006，5，： | 1 |
| 20 | AgDscam,a hypervariable immunoglobulin domain-containing receptor of the Anopheles gambiae innate immune system显示文摘 | Dong Y Taylor HE Dimopoulos G | | 0，，07： | 1 |
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