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| 1 | Early palliative care for patients with metastatic non-small-cell lung cancer显示文摘Comments This landmark article demonstrates that integration of early palliative care with standard oncologic practice shortly after diagnosis may improve quality of life,mood,and overall survival for adults with advanced non-small-cell lung cancer(NSCLC).If validated,these findings could support a paradigm shift in the care of adults with metastatic NSCLC and possibly patients with other tumor types characterized by short survival and high symptom burden. | Temel JS Greer JA Muzikansky A Gallagher ER Admane S Jackson VA Dahlin CM Blinderman CD Jacobsen J Pirl WF Billings JA Lynch TJ | 2010 | 中国肺癌杂志2010，13，9： | 165 |
| 2 | Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis显示文摘 | Rayner Katey J Sheedy Frederick J Esau Christine C Hussain Farah N Temel Ryan E Parathath Saj van Gils Janine M Rayner Alistair J Chang Aaron N Suarez Yajaira Fernandez-Hernando Carlos Fisher Edward A Moore Kathryn J | 2011 | Journal of Clinical Investigation2011，，7： | 2 |
| 3 | A new framework for reverse cholesterol transport: Non-biliary contributions to reverse cholesterol transport显示文摘Reduction of low-density lipoprotein-cholesterol through statin therapy has only modestly decreased coronary heart disease (CHD)-associated mortality in developed countries, which has prompted the search for alternative therapeutic strategies for CHD. Major efforts are now focused on therapies that augment high-density lipoprotein (HDL)-mediated reverse cholesterol transport (RCT), and ultimately increase the fecal disposal of cholesterol. The process of RCT has long been thought to simply involve HDL-mediated delivery of peripheral cholesterol to the liver for biliary excretion out of the body. However, recent studies have revealed a novel pathway for RCT that does not rely on biliary secretion. This nonbiliary pathway rather involves the direct excretion of cholesterol by the proximal small intestine. Compared to RCT therapies that augment biliary sterol loss, modulation of non-biliary fecal sterol loss through the intestine is a much more attractive therapeutic strategy, given that excessive biliary cholesterol secretion can promote gallstone formation. However, we are at an early stage in understanding the molecular mechanisms regulating the non-biliary pathway for RCT, and much additional work is required in order to effectively target this pathway for CHD prevention. The purpose of this review is to discuss our current understanding of biliary and nonbiliary contributions to RCT with particular emphasis on the possibility of targeting the intestine as an inducible cholesterol secretory organ. | Ryan E Temel J Mark Brown | 2010 | World Journal of Gastroenterology2010，16，47： | 2 |
| 4 | Airway inflammatory markers in chronic obstructive pulmonary disease and healthy smokers显示文摘 | Hacievliyagil S S Mutlu L C Temel J | 2013 | Niger J Clin Pract2013，16，1： | 1 |
| 5 | The evolution of sexual dimorphism in animals: hypotheses and tests 显示文摘 | Hedrick AV Temeles E J | 1989 | Trends Ecol Evol1989，4，： | 1 |
| 6 | Does initial staging or tumor histology better identify asymptomatic brain metastases in patients with non-small cell lung cancer显示文摘 | SHI A A DIGUMARTHY S R TEMEL J S | 2006 | J Thorac Oncol2006，1，3： | 1 |
| 7 | Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis显示文摘 | Rayner Katey J Sheedy Frederick J Esau Christine C Hussain Farah N Temel Ryan E Parathath Saj van Gils Janine M Rayner Alistair J Chang Aaron N Suarez Yajaira Fernandez-Hernando Carlos Fisher Edward A Moore Kathryn J | 2011 | Journal of Clinical Investigation2011，，7： | 1 |
| 8 | Diosgenin stimulation of fecal cholesterol excretion in mice is not NPC1L1 dependent 显示文摘 | Temel R E Brown J M Ma Y Y | 2009 | Journal of Lipid Research2009，50，5： | 1 |
| 9 | The evolution of sexual dimorphism in animals: Hypotheses and tests 显示文摘 | HEDRICK A V TEMELES E J | 1989 | Trends in Ecology and Evolution1989，4，： | 1 |
| 10 | User profiling for the Melvil knowledge retrieval system显示文摘 | Furnkranz J Holzbaur C Temel R | 2002 | Applied Artificial Intelligence2002，，16： | 1 |
| 11 | Aggressiveness of care in a prospective cohort of patients with advanced NSCLC 显示文摘 | Temel JS McCannon J Greer JA | 2008 | Cancer2008，113，4： | 1 |
| 12 | The role of neighbors in territorial systems: When are they' dear enemies' 显示文摘 | Temeles E J | 1994 | Animal Behavior1994，47，： | 1 |
| 13 | Aggressiveness of care in a prospective cohort of patients with advanced NSCLC 显示文摘 | TEMEL J S MCCANNON J GREER J A | 2008 | Cancer2008，113，4： | 1 |
| 14 | Aggressiveness of care in a prospective cohort of patients with advanced NSCLC 显示文摘 | TEMEL J S McCANNON J GREER J A | 2008 | Cancer2008，113，4： | 1 |
| 15 | Enhancement of scavenger receptor class B type I-mediated selective cholesteryl ester uptake from apoA- I (-/- ) high density lipoprotein(HDL) by apolipoprotein A-I requires HDL reorganization by lecithin cholesterol acyltransferase显示文摘 | TEMEL R E PARKS J S WILLIAMS D L | 2003 | J Biol Chem2003，278，7： | 1 |
| 16 | Complexities of quality of life analysis in non-small cell lung cancer显示文摘 | Temel J | 2007 | J Support Oncol2007，5，1： | 1 |
| 17 | Outcome of cadevaric renal transplant patients treated for 10 years with cyclosporine显示文摘 | Marcen R Pascual J Temel JL | | 0，，01： | 1 |
| 18 | The evolution of sexual dimorphism in animals: hypotheses and tests 显示文摘 | Hedrick A V Temeles E J | 1989 | Trends Ecoi Evol1989，4，： | 1 |
| 19 | The integration of palliative care and on- cology : the evidence显示文摘 | Von Roenn JH Temel J | 2011 | Oncology(Williston Park)2011，25，13： | 1 |
| 20 | Deteriorating ischemic stroke: risk factors and prognosis显示文摘 | Davalos A Cendra E Temel J | 1990 | Neurology1990，40，12： | 1 |
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