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| 1 | Performance of 18-fluoro-2-deoxyglucose positron emission tomography for esophageal cancer screening显示文摘AIM To evaluate the performance of 18-fluoro-2-deoxyglucose positron emission tomography(FDG-PET) for esophageal cancer(EC) screening.METHODS We retrospectively analyzed the data of consecutive asymptomatic individuals who underwent FDG-PET and esophagogastroduodenoscopy(EGD) simultaneously for cancer screening at our institution from February 2004 to March 2013. In total, 14790 FDG-PET and EGD procedures performed for 8468 individuals were included in this study, and the performance of FDGPET for EC screening was assessed by comparing the results of FDG-PET and EGD, considering the latter as the reference.RESULTS Thirty-two EC lesions were detected in 28 individuals(31 squamous cell carcinomas and 1 adenocarcinoma). The median tumor size was 12.5 mm, and the depths of the lesions were as follows: Tis(n = 12), T1a(n = 15), and T1b(n = 5). Among the 14790 FDG-PET procedures, 51 examinations(0.3%) showed positive findings in the esophagus; only 1 was a true-positive finding. The screen sensitivity, specificity, positive predictive value, and negative predictive value of FDGPET for ECs were 3.6%(95%CI: 0.1-18.3), 99.7%(95%CI: 99.6-99.7), 2.0%(95%CI: 0.0-10.4), and 99.8%(95%CI: 99.7-99.9), respectively. Of the 50 FDG-PET false-positive cases, 31 were observed in the lower esophagus, and gastroesophageal reflux disease was observed in 17 of these 31 cases.CONCLUSION This study is the first to clarify the FDG-PET performance for EC screening. Based on the low screen sensitivity, FDG-PET is considered to be difficult to use as a screening modality for ECs. | Masau Sekiguchi Takashi Terauchi Yasuo Kakugawa Naoki Shimada Yutaka Saito Takahisa Matsuda | 2017 | World Journal of Gastroenterology2017，23，15： | 3 |
| 2 | Disruption of adiponectin causes insulin resistance and neointimal formation 显示文摘 | Kubota N Terauchi Y Yamauchi T | 2002 | J Biol Chem2002，227，25： | 1 |
| 3 | Disruption ofinsulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia 显示文摘 | Kubota N Tobe K Terauchi Y etal | 2000 | Diabetes2000，49，11： | 1 |
| 4 | The mechanism by which PPAR gamma and adiponectin-regulate glucose and lipid metabolism 显示文摘 | Kamnon J Yanmuchi T Terauchi Y | 2003 | Nippon YalKutigaku Zasshi2003，122，： | 1 |
| 5 | 显示文摘 | Umehara H Takaya M Terauchi S | 2003 | Surface and Coatings Technology2003，，： | 1 |
| 6 | Disruption of adiponectin causes insulin resistance and neointimal formation 显示文摘 | Kubota N Terauchi Y Yamauehi T | 2002 | J Bio Chem2002，227，25： | 1 |
| 7 | Well-defined block copolymers comprising styrene-acrylonitrile random copolymer sequences synthesized by 'Living' radical polymerization显示文摘 | Fukuda T Terauchi T Goto A | 1996 | Macromolecules1996，29，8： | 1 |
| 8 | Disruption of adiponectin causes insulin resistance and neointimal formation显示文摘 | Kubota N Terauchi Y Yamauchi T | 2002 | J Biol Chem2002，277，25： | 1 |
| 9 | Development of noninsulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and β cell glucokinase genes显示文摘 | Terauchi Y Iwamoto K Tamemoto H | 1997 | J Clin Invest1997，99，： | 1 |
| 10 | Glucokinase and IRS-2 are required for compensatory beta-cell hyperplasia in response to high-fat diet-induced insulin resistance显示文摘 | Terauchi Y Takamoto I Kubota N | | 0，，： | 1 |
| 11 | Magnetic resonance angiography e-valuation of the bone tunnel and graft following ACL reconstructionwith a hamstring tendon autograft显示文摘 | Terauchi R Arai Y Hara K | 2014 | Knee Surg Sports TraumatolArthrosc2014，1，： | 1 |
| 12 | Mutation in OsLMS, a gene encoding a protein with two double-stranded RNA binding motifs, causes lesion mimic phenotype and early senescence in rice ( Oryza sativa )显示文摘 | Undan J Tamiru M Abe A Yoshida K Kosugi S Takagi H Yoshida K Kanzaki H Saitoh H Fekih R Sharma S Undan J Yano M Terauchi R | 2012 | Genes Genetic System2012，87，3： | 1 |
| 13 | Dynamic behavior of planetary gear (7th report: Influence of the thickness of the ring gear)显示文摘 | HIDAKA T TERAUCHI Y NAGAMURA K | 1979 | Bulletin of JSME1979，22，： | 1 |
| 14 | Disruption of adiponectin causes insulin resistance and neointimal formation显示文摘 | Kubota N Terauchi Y Yamauchi T | 2002 | J Biol Chem2002，277，25： | 1 |
| 15 | Chrome-free surface tueatments for magnesium alloy 显示文摘 | Umehara H Takaya M Terauchi S | 2003 | Surface and Coatings Technology2003，169，2： | 1 |
| 16 | Differential expres sion of wheat aspartic proteinases, WAP1 and WAP2, in ger minating and maturing seeds 显示文摘 | Tamura T Terauchi K Kiyosaki T | 2007 | Journal of Plant Physiology2007，164，： | 1 |
| 17 | Disruption of adiponectin causes in resistance and neointimal formation 显示文摘 | Kubota N Terauchi Y Yamauchi T | 2002 | J Biol Chem2002，227，25： | 1 |
| 18 | Tobacco ZFT1, a Transcriptional Repressor with a Cys 2 /His 2 Type Zinc Finger Motif that Functions in Spermine-Signaling Pathway显示文摘 | Yukiko Uehara Yoshihiro Takahashi Thomas Berberich Atsushi Miyazaki Hideki Takahashi Kyoko Matsui Masaru Ohme-Takagi Hiromasa Saitoh Ryohei Terauchi Tomonobu Kusano | 2005 | Plant Molecular Biology2005，，3： | 1 |
| 19 | Disruption of adiponectin auses insulin resistance and neointimal formation显示文摘 | Kubota N Terauchi Y Yamauchi T | 2002 | J Biol Chem2002，277，25： | 1 |
| 20 | Disruption of adiponectin causes insulin resistance and neointimalformation 显示文摘 | Kubota N Terauchi Y Yamauchi T | 2002 | J Biol Chem2002，277，25： | 1 |
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