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| 1 | Impact of periampullary diverticula on the outcome and fluoroscopy time in endoscopic retrograde cholangiopancreatography显示文摘BACKGROUND: It is unclear whether the presence of periampullary diverticula (PAD) affects technical success and complication rates during endoscopic retrograde cholangio- pancreatography (ERCP). Moreover, the impact of PAD on fluoroscopy duration is still unknown. The present study aimed to investigate the success rate and difficulty of common bile duct (CBD) cannulation, post-procedure complications and fluoroscopy duration in patients with and without PAD. METHODS: Patients from January 2008 to December 2010 with PAD (group A) and without PAD (group B) and similar indications for therapeutic ERCP were prospectively compared. The comparison included patient characteristics, findings of ERCP, and details of procedure and fluoroscopy time. The influence of papilla's location with respect to the diverticulum on procedure was also investigated. RESULTS: A total of 428 consecutive patients who had undergone therapeutic ERCP for similar indications were divided in two groups according to the presence (group A, 107 patients) or absence (group B, 321 patients) of PAD. The mean age and ASA score of the patients with PAD were significantly higher than those patients without PAD. The main indication was choledocholithiasis. Successful final CBD cannulation was achieved in 97.20% of the patients in group A vs 99.69% in group B (P=0.05). CBD diameter, number of stones and the largest stone size were significantly higher in group A thangroup B (P<0.001). Complete clearance of the CBD after the first attempt was achieved in 85.86% and 94.75% of the patients in groups A and B, respectively (P=0.03). In both groups, the time needed to complete the procedure and fluoroscopy time was significantly longer in patients with PAD (22.87 vs 18.99 minutes, P<0.001; 76.51 vs 47.42 seconds, P<0.001). There was no significant difference between the two groups in the complication rate. The type of papilla's location with respect to the diverticulum did not influence the total cannulation rate and post-procedure complications. CONCLUSION: The presence of a PAD does not affect the success rate and complications of therapeutic ERCP in expert hands; however, the fluoroscopy time is significantly longer in patients with PAD. | Panagiotis Katsinelos Grigoris Chatzimavroudis Kostas Tziomalos Christos Zavos Athanasios Beltsis Georgia Lazaraki Sotiris Terzoudis Jannis Kountouras | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，4： | 15 |
| 2 | Partially covered vs uncovered sphincterotome and postendoscopic sphincterotomy bleeding显示文摘AIM: To prospectively compare partially covered vs uncovered sphincterotome use on post-endoscopic biliary sphincterotomy (ES) hemorrhage and other complications. METHODS: All patients referred for therapeutic endoscopic retrograde cholangiopancreatography (ERCP) were randomly assigned to undergo ES either with a partially covered or an uncovered sphincterotome. Both patient and technical risk factors contributing to the development of post-ES bleeding were recorded and analyzed. The characteristics of bleeding was recorded during and after ES. Other complications were also compared. RESULTS: Three-hundred and eighty-seven patients were recruited in this study; 194 patients underwent ES with a partially covered sphincterotome and 193 with conventional uncovered sphincterotome. No statistical difference was noted in the baseline characteristics and risk factors for post-ES induced hemorrhage between the 2 groups. No significant difference in the incidence and pattern of visible bleeding rates was found between the 2 groups (immediate bleeding in 24 patients with the partially covered sphincterotome vs 19 patients with the uncovered sphincterotome, P = 0.418). Delayed bleeding was observed in 2 patients with a partially covered sphincterotome and in 1 patient with an uncovered sphincterotome (P = 0.62). No statistical difference was noted in the rate of other complications. CONCLUSION: The partially covered sphincterotome was not associated with a lower frequency of bleeding. Also, there was no difference in the incidence of other significant complications between the 2 types of sphincterotome. | Panagiotis Katsinelos George Paroutoglou Jannis Kountouras Grigoris Chatzimavroudis Christos Zavos Sotiris Terzoudis Taxiarchis Katsinelos Kostas Fasoulas George Gelas George Tzovaras Ioannis Pilpilidis | 2010 | World Journal of Gastroenterology2010，16，40： | 5 |
| 3 | Combination of diclofenac plus somatostatin in the prevention of post-ERCP pancreatitis: a randomized, double-blind, placebo-controlled trial显示文摘 | P. Katsinelos K. Fasoulas G. Paroutoglou G. Chatzimavroudis A. Beltsis S. Terzoudis T. Katsinelos E. Dimou C. Zavos A. Kaltsa J. Kountouras | 2012 | Endoscopy2012，，01： | 2 |
| 4 | Endoscopic management of occluded biliary uncovered metal stents:A multicenter experience显示文摘AIM:To compare diverse endoscopic interventions in the management of occluded uncovered self-expanding metal stents(SEMSs) that had been placed for palliative treatment of unresectable malignant biliary obstruction.METHODS:A retrospective review was undertaken in 4 tertiary endoscopic centers to determine optimal management of different types of occluded SEMSs.The technical success of performed treatment in occluded SEMSs,the patency of the stent,the need for re-intervention and the financial costs of each treatment were analyzed.RESULTS:Fifty four patients were included in the analysis;21 received Hanaro,19 Wallstent and 14 Flexus.For the relief of obstruction,a plastic stent was inserted in 24 patients,a second SEMS in 25 and mechanical cleaning was performed in 5 patients.The overall median second patency rates between second SEMSs and plastic stents did not differ(133 d for SEMSs vs 106 d for plastic stents;P = 0.856).Similarly,no difference was found between the overall survival of SEMS and plastic stent groups,and no procedure-related complications occurred.Incremental cost analysis showed that successive plastic stenting was a cost-saving strategy at least in Greece.CONCLUSION:Insertion of uncovered SEMSs or plastic stents is a safe and effective treatment for occluded uncovered SEMSs;insertion of plastic stents appears to be the most cost-effective strategy. | Panagiotis Katsinelos Athanasios Beltsis Grigoris Chatzimavroudis Dimitris Paikos George Paroutoglou Dimitris Kapetanos Sotiris Terzoudis Georgia Lazaraki Ioannis Pilpilidis Kostas Fasoulas Stefanos Atmatzidis Christos Zavos Jannis Kountouras | 2011 | World Journal of Gastroenterology2011，17，1： | 2 |
| 5 | Sleep architecture in stroke and relation to outcome显示文摘 | Terzoudi A Vorvolakos T Heliopoulos | 2009 | Eur Neuro12009，61，1： | 1 |
| 6 | Diagnostic yield and clinical management after capsule endoscopy in daily clinical practice: A single-center experience显示文摘 | P Katsinelos K Fasoylas Gr Chatzimavroudis G Lazaraki C Zavos I Pilpilidis S Terzoudis G Kokonis I Patsis A Beltsis G Parouto- glou and J Kountouras | 2010 | Hippokratia2010，14，4： | 1 |
| 7 | Sleep architecture in stroke and relation to outcome 显示文摘 | Terzoudi A Vorvolakos T Heliopoulos I | 2009 | Eur Neurol2009，61，1： | 1 |
| 8 | Checkpoint abrogation in G2 compromises repair of chromosoma breaks in ataxia telangiectasia cells显示文摘 | Terzoudi GI Manola KN Pantelias GE | | 0，，： | 1 |
| 9 | Sleep architec- ture in stroke and relation to outcome显示文摘 | Terzoudi A Vorvolakos T Heliopoulos I | 2009 | Eur Neurol2009，61，1： | 1 |
| 10 | Sleep architecture in stroke and relation to outcome显示文摘 | Terzoudi A Vorvolakos T Heliopoulos I | 2009 | Eur Neurol2009，61，1： | 1 |
| 11 | Sleep architecture in stroke and relation to outcome显示文摘 | Terzoudi A Vorvolakos T Heliopoulos | 2009 | Eur Neurol2009，61，1： | 1 |
| 12 | Cytogenetic methods for biodosimetry and risk individualisation after exposure to ionising radiation 显示文摘 | Terzoudi GI Pantelias GE | 2006 | Radiat Prot Dosimetry2006，22，14： | 1 |
| 13 | Sleep architecture in stroke and relation to outcome显示文摘 | Terzoudi A Vorvolakos T Heliopoulos I | 2009 | Eur Neurol2009，61，1： | 1 |
| 14 | The benzene metabolite hydroquinone enhances G2 - chromosomal radiosensitivity by inducing a less - efficient G2 - M - checkpoint in irradiated lymphocytes显示文摘 | Hatzi VI Terzoudi GI Pantelias GE | 2007 | International Journal of Oncology2007，31，： | 1 |
| 15 | Sleep architecture in stroke and relation to outcome显示文摘 | Terzoudi A Vorvolakos T Heliopoulos I | 2009 | Eur Neurol2009，61，1： | 1 |
| 16 | Sleep archi- tecture in stroke and relation to outcome 显示文摘 | Terzoudi A Vorvolakos T Heliopoulos I | 2009 | Eur Neurol2009，61，1： | 1 |
| 17 | Sleep architecture instroke and relation to outcome 显示文摘 | Terzoudi A Vorvolakos T Heliopoulos I | 2009 | Eur Neurol2009，61，2： | 1 |
| 18 | Sleep Architecture in Stroke and Relation to Outcome显示文摘 | Terzoudi A Vorvolakos T Heliopoulos I Livaditis M Vadikolias K Piperidou H | 2008 | European Neurology2008，，1： | 1 |
| 19 | Sleep ar- chitecture in stroke and relation to outcome显示文摘 | Terzoudi A Vorvolakos T Heliopoulos I | 2009 | Eur Neu- rol2009，61，1： | 1 |
| 20 | Large-balloon dilation of the biliary orifice for the management of basket impaction: a case series of 6 patients显示文摘 | Panagiotis Katsinelos Kostas Fasoulas Athanasios Beltsis Grigoris Chatzimavroudis Christos Zavos Sotiris Terzoudis Jannis Kountouras | 2011 | Gastrointestinal Endoscopy2011，，6： | 1 |
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