3篇
您的检索式：作者名="Thomas Engstrand"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Keratinocytes inhibit expression of connective tissue growth factor in fibroblasts in vitro by an interleukin-1α-dependent mechanism显示文摘 | Daniel Nowinski Patrik Hoijer Thomas Engstrand | 2002 | Invest Dermatol2002，119，： | 1 |
| 2 | Helicobacter pylori in ancient human remains显示文摘The bacterium Helicobacter pylori(H.pylori)infects the stomachs of approximately 50%of all humans.With its universal occurrence,high infectivity and virulence properties it is considered as one of the most severe global burdens of modern humankind.It has accompanied humans for many thousands of years,and due to its high genetic variability and vertical transmission,its population genetics reflects the history of human migrations.However,especially complex demographic events such as the colonisation of Europe cannot be resolved with population genetic analysis of modern H.pylori strains alone.This is best exemplified with the reconstruction of the 5300-year-old H.pylori genome of the Iceman,a European Copper Age mummy.Our analysis provided precious insights into the ancestry and evolution of the pathogen and underlined the high complexity of ancient European population history.In this review we will provide an overview on the molecular analysis of H.pylori in mummified human remains that were done so far and we will outline methodological advancements in the field of ancient DNA research that support the reconstruction and authentication of ancient H.pylori genome sequences. | Frank Maixner Kaisa Thorell Lena Granehall Bodo Linz Yoshan Moodley Thomas Rattei Lars Engstrand Albert Zink | 2019 | World Journal of Gastroenterology2019，25，42： | 0 |
| 3 | Bone without borders-Monetite-based calcium phosphate guides bone formation beyond the skeletal envelope显示文摘Calcium phosphates(CaP)represent an important class of osteoconductive and osteoinductive biomaterials.As proof-of-concept,we show how a multi-component CaP formulation(monetite,beta-tricalcium phosphate,and calcium pyrophosphate)guides osteogenesis beyond the physiological envelope.In a sheep model,hollow dome-shaped constructs were placed directly over the occipital bone.At 12 months,large amounts of bone(~75%)occupy the hollow space with strong evidence of ongoing remodelling.Features of both compact bone(osteonal/osteon-like arrangements)and spongy bone(trabeculae separated by marrow cavities)reveal insights into function/need-driven microstructural adaptation.Pores within the CaP also contain both woven bone and vascularised lamellar bone.Osteoclasts actively contribute to CaP degradation/removal.Of the constituent phases,only calcium pyrophosphate persists within osseous(cutting cones)and non-osseous(macrophages)sites.From a translational perspective,this multi-component CaP opens up exciting new avenues for osteotomy-free and minimally-invasive repair of large bone defects and augmentation of the dental alveolar ridge. | Furqan A.Shah Martina Jolic Chiara Micheletti Omar Omar Birgitta Norlindh Lena Emanuelsson Håkan Engqvist Thomas Engstrand Anders Palmquist Peter Thomsen | 2023 | Bioactive Materials2023，，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员