|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Relationship between obesity and cardiovascular risk factors in elderly Chinese subjects显示文摘Objective To investigate the relative effects of degree and distribution of body fat with several cardiovascular disease (CVD) risk factors in elderly Chinese subjects.Methods One-hundred and thirty-five elderly Chinese individuals (age range, 60-65 y) without any history of significant renal, hepatic or cardiac disease were recruited. Seated blood pressure, anthropometric and fasting plasma biochemical parameters were measured. Student’s t-test was used to compare the differences in biochemical and anthropometric markers between cohorts.Results Males were heavier (64.6±8.6, 57.2±8.2?kg, P<0.001), taller (1.65±0.06, 1.51± 0.05 m, P<0.001) and their greater body fat was predominantly deposited centrally (Waist-to-hip ratio, 0.91±0.06, 0.88±0.07, P<0.05). Females were more generally obese with increased body mass index (BMI, 23.8±4.6, 25.0±3.5 kg/m 2, P<0.05) and percentage body fat [26.3% (24.5%-28.1%) vs 37.2% (36.0%-38.9%), P<0.001] than the males. However, despite an 11% higher proportion of body fat in females, no significant differences were identified in blood pressure, lipid profile, indices of insulin resistance or albumin-to-creatinine ratios.Conclusion It is likely that central adiposity contributes disproportionately to these metabolic disorders in males even though they are much leaner than elderly Chinese females. | G Neil THOMAS 赵海潞 马艳青 Wilson YS LEUNG Juliana CN CHAN Brian TOMLINSON Julian AJH CRITCHLEY 梁润成 陈重娥 汤宁信 郭志良 | 2002 | Chinese Medical Journal2002，，6： | 11 |
| 2 | A Versatile Phenotyping System and Analytics Platform Reveals Diverse Temporal Responses to Water Availability in Setaria显示文摘Phenotyping 在使用大规模 genomic 数据理解并且改善农业庄稼成为了限制率的步。这里,为控制环境植物生长的系铃羊 Phenotyping 站台和 automatedmultimodal phenotyping 被描述。系统为 1140 植物有能力,它每天通过车站过去记录荧光,在红外线附近、可见的图象。植物计算机视觉(PlantCV ) 作为公开源码被开发,硬件为量的图象分析的与平台无关的软件。在一个 4 星期的实验,野 Setaria viridisand 驯养了 Setaria italica 有根本上不同的时间的回答浇可获得性。当两根线在有限的水条件下面生产了生物资源的类似的层次时, Setaria viridis 在水下面维持了一样的水使用效率饱满条件,当 Setaria italica 变了到不太有效的生长时。总的来说,系铃羊 Phenotyping 平台和 PlantCV 软件在高度,生物资源,水使用效率,颜色,植物建筑学,和织物水上检测了 genotypeand 环境的重要效果地位特点。在实验的功课期间获得的所有 ∼79000 图象是公开可得到的。 | Noah Fahlgren Maximilian Feldman Malia A. Gehan Melinda S. Wilson Christine Shyu Douglas W. Bryant Steven T. Hill Colton J. McEntee ankalpi N. Warnasooriya Indrajit Kumar Tracy Ficor Stephanie Turnipseed Kerrigan B. Gilbert Thomas P. Brutnell James C. Carrington Todd C. Mockler Ivan Baxter | 2015 | Molecular Plant2015，8，10： | 4 |
| 3 | Silvicultural alternatives to conventional even-aged forest man-agement-what limits global adoption?显示文摘Background: The development of forestry as a scientific and management discipline over the last two centuries has mainly emphasized intensive management operations focused on increased commodity production, mostly wood. This 'conventional' forest management approach has typically favored production of even-aged, single-species stands. While alternative management regimes have generally received less attention, this has been changing over the last three decades, especially in countries with developed economies. Reasons for this change include a combination of new information and concerns about the ecological consequences of intensive forestry practices and a willingness on the part of many forest owners and society to embrace a wider set of management objectives. Alternative silvicultural approaches are characterized by a set of fundamental principles, including avoidance of clearcutting, an emphasis on structural diversity and small-scale variability, deployment of mixed species with natural regeneration,and avoidance of intensive site-preparation methods.Methods: Our compilation of the authors' experiences and perspectives from various parts of the world aims to initiate a larger discussion concerning the constraints to and the potential of adopting alternative silvicultural practices.Results: The results suggest that a wider adoption of alternative silvicultural practices is currently hindered by a suite of ecological, economic, logistical, informational, cultural, and historical constraints. Individual contexts display their own unique combinations and relative significance of these constraints, and accordingly, targeted efforts, such as regulations and incentives, may help to overcome specific challenges.Conclusions: In a broader context, we propose that less emphases on strict applications of principles and on stand structures might provide additional flexibility and facilitate the adoption of alternative silvicultural regimes in a broader set of circumstances. At the same time, the acceptance of alternative silvicultural systems as the 'preferred or default mode of management' wil necessitate and benefit from the continued development of the scientific basis and valuation of a variety of ecosystem goods and services. This publication is aimed to further the discussion in this context. | Klaus J Puettmann Scott McG Wilson Susan C Baker Pablo J Donoso Lars Dr?ssler Girma Amente Brian D Harvey Thomas Knoke Yuanchang Lu Susanna Nocentini Francis E Putz Toshiya Yoshida Jürgen Bauhus | 2015 | Forest Ecosystems2015，2，2： | 4 |
| 4 | Nanocomposites for electronic applications that can be embedded for textiles and wearables显示文摘In the present review, we have selected advances in electrospinning nanofibers that we envision to be embedded in textiles and wearables. These nanofibers have been proven to be excellent options for applications such as power generation, sensing, and communication. Their similitude with already known woven meshes makes these fibers perfect for electronically active textiles.These fibers offer well known characteristics such as mechanical flexibility, high surface area-to-volume ratio, light weight and can be tuned by carefully selecting the active materials in the precursor solution. Here we will discuss polymers with electroactive, piezoelectric, triboelectric and their composites that have been used in fiber structures by using the electrospinning technique. | SERRANO-GARCIA William JAYATHILAKA Wanasinghe Arachchige Dumith Madushanka CHINNAPPAN Amutha TRAN Thang Quyet BASKAR Chinnappan THOMAS Sylvia Wilson RAMAKRISHNA Seeram | 2019 | Science China(Technological Sciences)2019，62，6： | 3 |
| 5 | Changes in the colon microbiota and intestinal cytokine gene expression following minimal intestinal surgery显示文摘AIM: To investigate the impact of minor abdominal surgery on the caecal microbial population and on markers of gut inflammation.METHODS: Four week old piglets were randomly allocated to a no-surgery 'control' group(n = 6) or a 'transection surgery' group(n = 5).During the transection surgery procedure, a conventional midline incision of the lower abdominal wall was made and the small intestine was transected at a site 225 cm proximal to the ileocaecal valve, a 2 cm segment was removed and the intestine was re-anastomosed.Piglets received a polymeric infant formula diet throughout the study period and were sacrificed at two weeks post-surgery.Clinical outcomes including weight, stool consistency and presence of stool fat globules were monitored.High throughput DNA sequencing of colonic content was used to detect surgery-relateddisturbances in microbial composition at phylum, family and genus level.Diversity and richness estimates were calculated for the control and minor surgery groups.As disturbances in the gut microbial community are linked to inflammation we compared the gene expression of key inflammatory cytokines(TNF, IL1 B, IL18, IL12, IL8, IL6 and IL10) in ileum, terminal ileum and colon mucosal extracts obtained from control and abdominal surgery groups at two weeks post-surgery.RESULTS: Changes in the relative abundance of bacterial species at family and genus level were confined to bacterial members of the Proteobacteria and Bacteroidetes phyla.Family level compositional shifts included a reduction in the relative abundance of Enterobacteriaceae(22.95 ± 5.27 vs 2.07 ± 0.72, P < 0.01), Bacteroidaceae(2.54 ± 0.56 vs 0.86 ± 0.43, P < 0.05) and Rhodospirillaceae(0.40 ± 0.14 vs 0.00 ± 0.00, P < 0.05) following transection surgery.Similarly, at the genus level, changes associated with transection surgery were restricted to members of the Proteobacteria and Bacteroidetes phyla and included decreased relative abundance of Enterobacteriaceae(29.20 ± 6.74 vs 2.88 ± 1.08, P < 0.01), Alistipes(4.82 ± 1.73 vs 0.18 ± 0.13, P < 0.05) and Thalassospira(0.53 ± 0.19 vs 0.00 ± 0.00, P < 0.05).Surgeryassociated microbial dysbiosis was accompanied by increased gene expression of markers of inflammation.Within the ileum IL6 expression was decreased(4.46 ± 1.60 vs 0.24 ± 0.06, P < 0.05) following transection surgery.In the terminal ileum, gene expression of TNF was decreased(1.51 ± 0.13 vs 0.80 ± 0.16, P < 0.01) and IL18(1.21 ± 0.18 vs 2.13 ± 0.24, P < 0.01), IL12(1.04 ± 0.16 vs 1.82 ± 0.32, P < 0.05) and IL10(1.04 ± 0.06 vs 1.43 ± 0.09, P < 0.01) gene expression increased following transection surgery.Within the colon, IL12(0.72 ± 0.13 vs 1.78 ± 0.28, P < 0.01) and IL10(0.98 ± 0.02 vs 1.95 ± 0.14, P < 0.01) gene expression were increased following transection surgery.CONCLUSION: This study suggests that minor abdominal surgery in infants, results in long-term alteration of the colonic microbial composition and persistent gastrointestinal inflammation. | Susan Lapthorne Julie E Bines Fiona Fouhy Nicole L Dellios Guineva Wilson Sarah L Thomas Michelle Scurr Catherine Stanton Paul D Cotter Prue M Pereira-Fantini | 2015 | World Journal of Gastroenterology2015，21，14： | 3 |
| 6 | Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Statement for Health Professionals From the Committee on Rheumatic Fever, Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association显示文摘 | Jane W. Newburger Masato Takahashi Michael A. Gerber Michael H. Gewitz Lloyd Y. Tani Jane C. Burns Stanford T. Shulman Ann F. Bolger Patricia Ferrieri Robert S. Baltimore Walter R. Wilson Larry M. Baddour Matthew E. Levison Thomas J. Pallasch Donald A. Fa | 2004 | Circulation2004，，17： | 2 |
| 7 | Hepatitis C Virus Infects the Endothelial Cells of the Blood-Brain Barrier显示文摘 | Nicola F. Fletcher Garrick K. Wilson Jacinta Murray Ke Hu Andrew Lewis Gary M. Reynolds Zania Stamataki Luke W. Meredith Ian A. Rowe Guangxiang Luo Miguel A. Lopez–Ramirez Thomas F. Baumert Babette Weksler Pierre–Olivier Couraud Kwang Sik Kim Ignacio A. R | 2012 | Gastroenterology2012，，3： | 2 |
| 8 | Intra-and inter-specific mitochondrial DNA sequences divergence in salmo:rainbow,steelhead,and cutthroat trouts显示文摘 | Wilson G M Thomas W K Beckenbach A T | 1985 | Can J Zool1985，，63： | 2 |
| 9 | Integrative Genomic Profiling of Human Prostate Cancer显示文摘 | Barry S. Taylor Nikolaus Schultz Haley Hieronymus Anuradha Gopalan Yonghong Xiao Brett S. Carver Vivek K. Arora Poorvi Kaushik Ethan Cerami Boris Reva Yevgeniy Antipin Nicholas Mitsiades Thomas Landers Igor Dolgalev John E. Major Manda Wilson Nicholas D. | 2010 | Cancer Cell2010，，： | 2 |
| 10 | Colitis and Intestinal Inflammation in IL10 ?/? Mice Results From IL-13Rα2–Mediated Attenuation of IL-13 Activity显示文摘 | Mark S. Wilson Thirumalai R. Ramalingam Aymeric Rivollier Kevin Shenderov Margaret M. Mentink–Kane Satish K. Madala Allen W. Cheever David Artis Brian L. Kelsall Thomas A. Wynn | 2011 | Gastroenterology2011，，1： | 2 |
| 11 | Cell cycle alterations associated with covalent binding of monocrotaline pyrrole to pulmonary artery endothelial cell DNA 显示文摘 | Thomas HC Lame MW Wilson DW | 1996 | Toxicol Appl Pharmacol1996，141，3： | 1 |
| 12 | Acute oxaliplatin-induced peripheral nerve hyperexcitability 显示文摘 | WILSON R H LEHKY T THOMAS R R | 2002 | Clin Oncol2002，20，7： | 1 |
| 13 | Predictors of Comprehension during Surgical Informed Consent显示文摘 | Aaron S. Fink Allan V. Prochazka William G. Henderson Debra Bartenfeld Carsie Nyirenda Alexandra Webb David H. Berger Kamal Itani Thomas Whitehill James Edwards Mark Wilson Cynthia Karsonovich Patricia Parmelee | 2010 | Journal of the American College of Surgeons2010，，6： | 1 |
| 14 | Evolution of the cytochromeb gene of mammals显示文摘 | David M. Irwin Thomas D. Kocher Allan C. Wilson | 1991 | Journal of Molecular Evolution1991，，2： | 1 |
| 15 | Linear order statistic estimation for the two parameter Weibull and extreme-vMue distribution under Type-II progressively censored samples 显示文摘 | Thomas D R and Wilson W M | 1972 | Technometrics1972，14，： | 1 |
| 16 | Gibberellin control of stamen development:a fertile field显示文摘 | Plackett A R Thomas S G Wilson Z A | | 0，，10： | 1 |
| 17 | Scale Transitions in Fracture and Active Fault Networks显示文摘 | Thomas H. Wilson | 2001 | Mathematical Geology2001，，5： | 1 |
| 18 | Acute oxaliplatin-induced peripheral nerve hyperexcitability显示文摘 | Wilson RH Lehky T Thomas RR | 2002 | Clin Oncol2002，20，7： | 1 |
| 19 | Social Functioning and Overall Mortality: Prospective Evidence from the Kuopio Ischemic Heart Disease Risk Factor Study显示文摘 | George A. Kaplan Thomas W. Wilson Richard D. Cohen Jussi Kauhanen Melien Wu Jukka T. Salonen | 1994 | Epidemiology1994，，5： | 1 |
| 20 | Acute oxaliplatin-induced peripheral nerve hyperexcitability显示文摘 | Wilson RH Lehky T Thomas RR | 2002 | J Clin Oncol2002，20，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员